4PKG
 
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4PKH
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8TAH
 | | Cryo-EM structure of Cortactin-bound to Arp2/3 complex | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1A, ... | | Authors: | Fregoso, F.E, van Eeuwen, T, Dominguez, R. | | Deposit date: | 2023-06-27 | | Release date: | 2023-09-27 | | Last modified: | 2024-01-31 | | Method: | ELECTRON MICROSCOPY (2.89 Å) | | Cite: | Mechanism of synergistic activation of Arp2/3 complex by cortactin and WASP-family proteins.
Nat Commun, 14, 2023
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7T5Q
 | | Cryo-EM Structure of a Transition State of Arp2/3 Complex Activation | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | Authors: | Rebowski, G, van Eeuwen, T, Boczkowska, M, Dominguez, R. | | Deposit date: | 2021-12-13 | | Release date: | 2023-06-14 | | Last modified: | 2023-08-02 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Cryo-EM structure of an Arp2/3 complex mini-branch capped by capping protein (CapZ)
To Be Published
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8F8T
 | | Cryo-EM structure of the Tropomodulin-capped pointed end of F-actin | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Carman, P.J, Barrie, K.R, Dominguez, R. | | Deposit date: | 2022-11-22 | | Release date: | 2023-06-07 | | Last modified: | 2023-07-05 | | Method: | ELECTRON MICROSCOPY (3.26 Å) | | Cite: | Structures of the free and capped ends of the actin filament.
Science, 380, 2023
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8F8S
 | | Cryo-EM structure of the free pointed end of F-actin | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Carman, P.J, Barrie, K.R, Dominguez, R. | | Deposit date: | 2022-11-22 | | Release date: | 2023-06-07 | | Last modified: | 2023-07-05 | | Method: | ELECTRON MICROSCOPY (2.84 Å) | | Cite: | Structures of the free and capped ends of the actin filament.
Science, 380, 2023
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8F8Q
 | | Cryo-EM structure of the CapZ-capped barbed end of F-actin | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Carman, P.J, Barrie, K.R, Dominguez, R. | | Deposit date: | 2022-11-22 | | Release date: | 2023-06-07 | | Last modified: | 2023-07-05 | | Method: | ELECTRON MICROSCOPY (2.79 Å) | | Cite: | Structures of the free and capped ends of the actin filament.
Science, 380, 2023
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8F8R
 | | Cryo-EM structure of the free barbed end of F-actin | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Carman, P.J, Barrie, K.R, Dominguez, R. | | Deposit date: | 2022-11-22 | | Release date: | 2023-06-07 | | Last modified: | 2023-07-05 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structures of the free and capped ends of the actin filament.
Science, 380, 2023
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8F8P
 | | Cryo-EM structure of F-actin in the ADP state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Carman, P.J, Barrie, K.R, Dominguez, R. | | Deposit date: | 2022-11-22 | | Release date: | 2023-06-07 | | Last modified: | 2023-07-05 | | Method: | ELECTRON MICROSCOPY (2.26 Å) | | Cite: | Structures of the free and capped ends of the actin filament.
Science, 380, 2023
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1S70
 | | Complex between protein ser/thr phosphatase-1 (delta) and the myosin phosphatase targeting subunit 1 (MYPT1) | | Descriptor: | 130 kDa myosin-binding subunit of smooth muscle myosin phophatase (M130), MANGANESE (II) ION, Serine/threonine protein phosphatase PP1-beta (or delta) catalytic subunit, ... | | Authors: | Kerff, F, Terrak, M, Dominguez, R. | | Deposit date: | 2004-01-28 | | Release date: | 2004-06-22 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis of protein phosphatase 1 regulation
Nature, 429, 2004
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1TN4
 | | FOUR CALCIUM TNC | | Descriptor: | CALCIUM ION, TROPONIN C | | Authors: | Love, M.L, Dominguez, R, Houdusse, A, Cohen, C. | | Deposit date: | 1997-09-18 | | Release date: | 1998-04-08 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structures of four Ca2+-bound troponin C at 2.0 A resolution: further insights into the Ca2+-switch in the calmodulin superfamily.
Structure, 5, 1997
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1M45
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1M46
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4EDQ
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1N2D
 | | Ternary complex of MLC1P bound to IQ2 and IQ3 of Myo2p, a class V myosin | | Descriptor: | IQ2 AND IQ3 MOTIFS FROM MYO2P, A CLASS V MYOSIN, Myosin Light Chain | | Authors: | Terrak, M, Wu, G, Stafford, W.F, Lu, R.C, Dominguez, R. | | Deposit date: | 2002-10-22 | | Release date: | 2003-11-04 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of the light chain-binding domain of myosin V.
Proc.Natl.Acad.Sci.USA, 102, 2005
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3M3N
 | | Structure of a Longitudinal Actin Dimer Assembled by Tandem W Domains | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Rebowski, G, Namgoong, S, Dominguez, R. | | Deposit date: | 2010-03-09 | | Release date: | 2010-07-28 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (7 Å) | | Cite: | Structure of a longitudinal actin dimer assembled by tandem w domains: implications for actin filament nucleation.
J.Mol.Biol., 403, 2010
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3M1F
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3CHW
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3CIP
 | | Complex of Dictyostelium Discoideum Actin with Gelsolin | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, GLYCEROL, ... | | Authors: | Baek, K, Dominguez, R. | | Deposit date: | 2008-03-11 | | Release date: | 2008-08-19 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Modulation of actin structure and function by phosphorylation of Tyr-53 and profilin binding.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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4J7O
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4JS0
 | | Complex of Cdc42 with the CRIB-PR domain of IRSp53 | | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Brain-specific angiogenesis inhibitor 1-associated protein 2, Cell division control protein 42 homolog, ... | | Authors: | Kast, D.J, Dominguez, R. | | Deposit date: | 2013-03-22 | | Release date: | 2014-03-05 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Mechanism of IRSp53 inhibition and combinatorial activation by Cdc42 and downstream effectors.
Nat.Struct.Mol.Biol., 21, 2014
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4K17
 | | Crystal Structure of mouse CARMIL residues 1-668 | | Descriptor: | CHLORIDE ION, GAMMA-AMINO-BUTANOIC ACID, Leucine-rich repeat-containing protein 16A, ... | | Authors: | Zwolak, A, Dominguez, R. | | Deposit date: | 2013-04-04 | | Release date: | 2013-10-09 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.895 Å) | | Cite: | CARMIL leading edge localization depends on a non-canonical PH domain and dimerization.
Nat Commun, 4, 2013
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4L79
 | | Crystal Structure of nucleotide-free Myosin 1b residues 1-728 with bound Calmodulin | | Descriptor: | Calmodulin, MAGNESIUM ION, Unconventional myosin-Ib | | Authors: | Shuman, H, Zwolak, A, Dominguez, R, Ostap, E.M. | | Deposit date: | 2013-06-13 | | Release date: | 2014-01-29 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | A vertebrate myosin-I structure reveals unique insights into myosin mechanochemical tuning.
Proc.Natl.Acad.Sci.USA, 111, 2014
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6UHC
 | | CryoEM structure of human Arp2/3 complex with bound NPFs | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, ... | | Authors: | Zimmet, A, van Eeuwen, T, Dominguez, R. | | Deposit date: | 2019-09-27 | | Release date: | 2020-07-01 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Cryo-EM structure of NPF-bound human Arp2/3 complex and activation mechanism.
Sci Adv, 6, 2020
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5WFN
 | | Revised model of leiomodin 2-mediated actin regulation (alternate refinement of PDB 4RWT) | | Descriptor: | Actin-5C, Leiomodin-2, MAGNESIUM ION, ... | | Authors: | Yurtsever, Z, Eck, M.J, Dominguez, R. | | Deposit date: | 2017-07-12 | | Release date: | 2017-08-30 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structure of leiomodin 2 in complex with actin: a structural and functional reexamination
Biophys.J., 113, 2017
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