1VHR
| HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE VHR, SULFATE ION | Authors: | Yuvaniyama, J, Denu, J.M, Dixon, J.E, Saper, M.A. | Deposit date: | 1996-02-20 | Release date: | 1996-06-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of the dual specificity protein phosphatase VHR. Science, 272, 1996
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8F48
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4ITR
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1UKF
| Crystal Structure of Pseudomonas Avirulence Protein AvrPphB | Descriptor: | Avirulence protein AVRPPH3 | Authors: | Zhu, M, Shao, F, Innes, R.W, Dixon, J.E, Xu, Z. | Deposit date: | 2003-08-21 | Release date: | 2003-12-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | The crystal structure of Pseudomonas avirulence protein AvrPphB: a papain-like fold with a distinct substrate-binding site. Proc.Natl.Acad.Sci.Usa, 101, 2004
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1DOF
| THE CRYSTAL STRUCTURE OF ADENYLOSUCCINATE LYASE FROM PYROBACULUM AEROPHILUM: INSIGHTS INTO THERMAL STABILITY AND HUMAN PATHOLOGY | Descriptor: | ADENYLOSUCCINATE LYASE | Authors: | Toth, E.A, Yeates, T.O, Goedken, E, Dixon, J.E, Marqusee, S. | Deposit date: | 1999-12-20 | Release date: | 2001-01-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The crystal structure of adenylosuccinate lyase from Pyrobaculum aerophilum reveals an intracellular protein with three disulfide bonds. J.Mol.Biol., 301, 2000
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1YTS
| A LIGAND-INDUCED CONFORMATIONAL CHANGE IN THE YERSINIA PROTEIN TYROSINE PHOSPHATASE | Descriptor: | SULFATE ION, YERSINIA PROTEIN TYROSINE PHOSPHATASE | Authors: | Schubert, H.L, Stuckey, J.A, Fauman, E.B, Dixon, J.E, Saper, M.A. | Deposit date: | 1995-04-07 | Release date: | 1995-07-10 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A ligand-induced conformational change in the Yersinia protein tyrosine phosphatase. Protein Sci., 4, 1995
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2QH7
| MitoNEET is a uniquely folded 2Fe-2S outer mitochondrial membrane protein stabilized by pioglitazone | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, Zinc finger CDGSH-type domain 1 | Authors: | Paddock, M.L, Wiley, S.E, Axelrod, H.L, Cohen, A.E, Roy, M, Abresch, E.C, Capraro, D, Murphy, A.N, Nechushtai, R, Dixon, J.E, Jennings, P.A. | Deposit date: | 2007-06-30 | Release date: | 2007-08-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | MitoNEET is a uniquely folded 2Fe 2S outer mitochondrial membrane protein stabilized by pioglitazone. Proc.Natl.Acad.Sci.Usa, 104, 2007
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1YPT
| CRYSTAL STRUCTURE OF YERSINIA PROTEIN TYROSINE PHOSPHATASE AT 2.5 ANGSTROMS AND THE COMPLEX WITH TUNGSTATE | Descriptor: | PROTEIN-TYROSINE PHOSPHATASE YERSINIA (CATALYTIC DOMAIN) | Authors: | Stuckey, J.A, Schubert, H.L, Fauman, E.B, Zhang, Z.-Y, Dixon, J.E, Saper, M.A. | Deposit date: | 1994-09-16 | Release date: | 1994-12-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of Yersinia protein tyrosine phosphatase at 2.5 A and the complex with tungstate. Nature, 370, 1994
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1BYR
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1BYS
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1LW3
| Crystal Structure of Myotubularin-related protein 2 complexed with phosphate | Descriptor: | Myotubularin-related protein 2, PHOSPHATE ION | Authors: | Begley, M.J, Taylor, G.S, Kim, S.-A, Veine, D.M, Dixon, J.E, Stuckey, J.A. | Deposit date: | 2002-05-30 | Release date: | 2003-10-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of a Phosphoinositide Phosphatase, MTMR2: Insights into Myotubular Myopathy and Charcot-Marie-Tooth Syndrome Mol.Cell, 12, 2003
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1M7R
| Crystal Structure of Myotubularin-related Protein-2 (MTMR2) Complexed with Phosphate | Descriptor: | Myotubularin-related Protein-2, PHOSPHATE ION | Authors: | Begley, M.J, Taylor, G.S, Kim, S.-A, Veine, D.M, Dixon, J.E, Stuckey, J.A. | Deposit date: | 2002-07-22 | Release date: | 2003-10-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of a phosphoinositide phosphatase, MTMR2: insights into myotubular myopathy and Charcot-Marie-Tooth syndrome Mol.Cell, 12, 2003
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1ZSQ
| Crystal Structure of MTMR2 in complex with phosphatidylinositol 3-phosphate | Descriptor: | 1,2-ETHANEDIOL, 2-(BUTANOYLOXY)-1-{[(HYDROXY{[2,3,4,6-TETRAHYDROXY-5-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTANOATE, Myotubularin-related protein 2 | Authors: | Begley, M.J, Taylor, G.S, Brock, M.A, Ghosh, P, Woods, V.L, Dixon, J.E. | Deposit date: | 2005-05-25 | Release date: | 2006-01-31 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Molecular basis for substrate recognition by MTMR2, a myotubularin family phosphoinositide phosphatase Proc.Natl.Acad.Sci.Usa, 103, 2006
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1ZVR
| Crystal Structure of MTMR2 in complex with phosphatidylinositol 3,5-bisphosphate | Descriptor: | (1S)-2-(1-HYDROXYBUTOXY)-1-{[(HYDROXY{[(2R,3S,5R,6S)-2,4,6-TRIHYDROXY-3,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTYRATE, 1,2-ETHANEDIOL, Myotubularin-related protein 2 | Authors: | Begley, M.J, Taylor, G.S, Brock, M.A, Ghosh, P, Woods, V.L, Dixon, J.E. | Deposit date: | 2005-06-02 | Release date: | 2006-01-31 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Molecular basis for substrate recognition by MTMR2, a myotubularin family phosphoinositide phosphatase Proc.Natl.Acad.Sci.Usa, 103, 2006
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6K0J
| The co-crystal structure of DYRK2 with a small molecule inhibitor | Descriptor: | 3-(2,7-dimethoxyacridin-9-yl)sulfanylpropan-1-amine, Dual specificity tyrosine-phosphorylation-regulated kinase 2 | Authors: | Tiantian, W, Xiao, J. | Deposit date: | 2019-05-06 | Release date: | 2019-11-20 | Last modified: | 2019-12-18 | Method: | X-RAY DIFFRACTION (2.352 Å) | Cite: | Inhibition of dual-specificity tyrosine phosphorylation-regulated kinase 2 perturbs 26S proteasome-addicted neoplastic progression. Proc.Natl.Acad.Sci.USA, 116, 2019
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5ZTN
| The crystal structure of human DYRK2 in complex with Curcumin | Descriptor: | (1Z,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one, Dual specificity tyrosine-phosphorylation-regulated kinase 2 | Authors: | Ji, C.G, Xiao, J.Y. | Deposit date: | 2018-05-04 | Release date: | 2018-07-18 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.496 Å) | Cite: | Ancient drug curcumin impedes 26S proteasome activity by direct inhibition of dual-specificity tyrosine-regulated kinase 2. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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3CXB
| Crystal Structure of sifa and skip | Descriptor: | Pleckstrin homology domain-containing family M member 2, Protein sifA | Authors: | Huang, Z, Chai, J. | Deposit date: | 2008-04-24 | Release date: | 2008-12-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure and function of Salmonella SifA indicate that its interactions with SKIP, SseJ, and RhoA family GTPases induce endosomal tubulation Cell Host Microbe, 4, 2008
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4KQB
| crystal structure of the Golgi casein kinase with Mn/ADP bound | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... | Authors: | Xiao, J. | Deposit date: | 2013-05-14 | Release date: | 2013-06-26 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.045 Å) | Cite: | Crystal structure of the Golgi casein kinase. Proc.Natl.Acad.Sci.USA, 110, 2013
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4KQA
| Crystal structure of the golgi casein kinase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NICKEL (II) ION, Protein H03A11.1, ... | Authors: | Xiao, J. | Deposit date: | 2013-05-14 | Release date: | 2013-06-26 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.603 Å) | Cite: | Crystal structure of the Golgi casein kinase. Proc.Natl.Acad.Sci.USA, 110, 2013
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1CDE
| STRUCTURES OF APO AND COMPLEXED ESCHERICHIA COLI GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE | Descriptor: | 5-DEAZAFOLIC ACID, GLYCINAMIDE RIBONUCLEOTIDE, PHOSPHORIBOSYL-GLYCINAMIDE FORMYLTRANSFERASE | Authors: | Almassy, R.J, Janson, C.A, Kan, C.-C, Hostomska, Z. | Deposit date: | 1992-05-15 | Release date: | 1993-10-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures of apo and complexed Escherichia coli glycinamide ribonucleotide transformylase. Proc.Natl.Acad.Sci.USA, 89, 1992
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5GZA
| protein O-mannose kinase | Descriptor: | 2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose, 4-METHYL-2H-CHROMEN-2-ONE, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Xiao, J. | Deposit date: | 2016-09-27 | Release date: | 2016-12-07 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of protein O-mannose kinase reveals a unique active site architecture Elife, 5, 2016
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3RGO
| Crystal Structure of PTPMT1 | Descriptor: | Protein-tyrosine phosphatase mitochondrial 1, SULFATE ION | Authors: | Xiao, J, Engel, J.L. | Deposit date: | 2011-04-08 | Release date: | 2011-07-06 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.928 Å) | Cite: | Structural and functional analysis of PTPMT1, a phosphatase required for cardiolipin synthesis. Proc.Natl.Acad.Sci.USA, 108, 2011
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2I42
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3SHQ
| Crystal Structure of UBLCP1 | Descriptor: | MAGNESIUM ION, UBLCP1 | Authors: | Xiao, J, Engel, J.L. | Deposit date: | 2011-06-16 | Release date: | 2011-10-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | UBLCP1 is a 26S proteasome phosphatase that regulates nuclear proteasome activity. Proc.Natl.Acad.Sci.USA, 108, 2011
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3RGQ
| Crystal Structure of PTPMT1 in complex with PI(5)P | Descriptor: | (2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,4,6-tetrahydroxy-5-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dibutanoate, Protein-tyrosine phosphatase mitochondrial 1 | Authors: | Xiao, J, Engel, J.L. | Deposit date: | 2011-04-08 | Release date: | 2011-07-06 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural and functional analysis of PTPMT1, a phosphatase required for cardiolipin synthesis. Proc.Natl.Acad.Sci.USA, 108, 2011
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