1M7R

Crystal Structure of Myotubularin-related Protein-2 (MTMR2) Complexed with Phosphate

Summary for 1M7R

• Entry DOI: 10.2210/pdb1m7r/pdb
• Related: 1LW3
• Descriptor: Myotubularin-related Protein-2, PHOSPHATE ION (3 entities in total)
• Functional Keywords: protein-phosphate complex, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm : Q13614
• Total number of polymer chains: 2
• Total formula weight: 150393.37

Authors

Begley, M.J.,Taylor, G.S.,Kim, S.-A.,Veine, D.M.,Dixon, J.E.,Stuckey, J.A. (deposition date: 2002-07-22, release date: 2003-10-07, Last modification date: 2024-02-14)

• Primary citation: Begley, M.J.,Taylor, G.S.,Kim, S.-A.,Veine, D.M.,Dixon, J.E.,Stuckey, J.A.; Crystal structure of a phosphoinositide phosphatase, MTMR2: insights into myotubular myopathy and Charcot-Marie-Tooth syndrome; Mol.Cell, 12:1391-1402, 2003; PubMed: 14690594; DOI: 10.1016/S1097-2765(03)00486-6

Experimental method

X-RAY DIFFRACTION (2.6 Å)