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7WWG
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BU of 7wwg by Molmil
Crystal structure of Saccharomyces cerevisiae Sfh2 complexed with phosphatidylinositol in an open conformation
Descriptor: (1R)-2-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, Phosphatidylinositol transfer protein CSR1
Authors:Chen, L, Tan, L, Im, Y.J.
Deposit date:2022-02-12
Release date:2022-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural basis of ligand recognition and transport by Sfh2, a yeast phosphatidylinositol transfer protein of the Sec14 superfamily.
Acta Crystallogr D Struct Biol, 78, 2022
7WWD
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BU of 7wwd by Molmil
Crystal structure of Saccharomyces cerevisiae Sfh2 complexed with squalene
Descriptor: (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene, Phosphatidylinositol transfer protein CSR1
Authors:Chen, L, Tan, L, Im, Y.J.
Deposit date:2022-02-12
Release date:2022-07-13
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structural basis of ligand recognition and transport by Sfh2, a yeast phosphatidylinositol transfer protein of the Sec14 superfamily.
Acta Crystallogr D Struct Biol, 78, 2022
7WVT
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BU of 7wvt by Molmil
Crystal structure of Saccharomyces cerevisiae Sfh2 complexed with phosphatidylinositol
Descriptor: (1R)-2-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, Phosphatidylinositol transfer protein CSR1
Authors:Chen, L, Tan, L, Im, Y.J.
Deposit date:2022-02-11
Release date:2022-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis of ligand recognition and transport by Sfh2, a yeast phosphatidylinositol transfer protein of the Sec14 superfamily.
Acta Crystallogr D Struct Biol, 78, 2022
7WWE
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BU of 7wwe by Molmil
Crystal structure of Saccharomyces cerevisiae Sfh2 in an apo form
Descriptor: Phosphatidylinositol transfer protein CSR1
Authors:Chen, L, Tan, L, Im, Y.J.
Deposit date:2022-02-12
Release date:2022-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of ligand recognition and transport by Sfh2, a yeast phosphatidylinositol transfer protein of the Sec14 superfamily.
Acta Crystallogr D Struct Biol, 78, 2022
7VUO
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BU of 7vuo by Molmil
Crystal Structure of the Kv7.1 C-terminal Domain in Complex with Calmodulin disease mutation F141L
Descriptor: CALCIUM ION, Calmodulin-1, Kv7.1
Authors:Chen, L.
Deposit date:2021-11-03
Release date:2022-11-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.679 Å)
Cite:Crystal Structure of the Kv7.1 C-terminal Domain in Complex with Calmodulin disease mutation F141L
To Be Published
7VVD
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BU of 7vvd by Molmil
Crystal Structure of the Kv7.1 C-terminal Domain in Complex with Calmodulin disease mutation Q135P
Descriptor: CALCIUM ION, Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 1,Potassium voltage-gated channel subfamily KQT member 1
Authors:Chen, L.
Deposit date:2021-11-05
Release date:2022-11-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.134 Å)
Cite:Crystal Structure of the Kv7.1 C-terminal Domain in Complex with Calmodulin disease mutation F141L
To Be Published
7VVH
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BU of 7vvh by Molmil
Crystal Structure of the Kv7.1 C-terminal Domain in Complex with Calmodulin disease mutation E140G
Descriptor: CALCIUM ION, Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 1,Potassium voltage-gated channel subfamily KQT member 1
Authors:Chen, L.
Deposit date:2021-11-06
Release date:2022-11-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.296 Å)
Cite:Crystal Structure of the Kv7.1 C-terminal Domain in Complex with Calmodulin disease mutation F141L
To Be Published
1AAN
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BU of 1aan by Molmil
CRYSTAL STRUCTURE ANALYSIS OF AMICYANIN AND APOAMICYANIN FROM PARACOCCUS DENITRIFICANS AT 2.0 ANGSTROMS AND 1.8 ANGSTROMS RESOLUTION
Descriptor: AMICYANIN, COPPER (II) ION
Authors:Chen, L, Durley, R.C.E, Lim, L.W, Mathews, F.S.
Deposit date:1992-04-09
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure analysis of amicyanin and apoamicyanin from Paracoccus denitrificans at 2.0 A and 1.8 A resolution.
Protein Sci., 2, 1993
8X2L
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BU of 8x2l by Molmil
Structure of human phagocyte NADPH oxidase in the resting state in the presence of 2 mM NADPH
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 7D5 Fab heavy chain, 7D5 Fab light chain, ...
Authors:Chen, L, Liu, X.
Deposit date:2023-11-09
Release date:2024-01-24
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.99 Å)
Cite:Structure of human phagocyte NADPH oxidase in the activated state.
Nature, 627, 2024
8WEJ
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BU of 8wej by Molmil
Structure of human phagocyte NADPH oxidase in the activated state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 7D5 Fab heavy chain, 7D5 Fab light chain, ...
Authors:Chen, L, Liu, X.
Deposit date:2023-09-18
Release date:2024-01-24
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Structure of human phagocyte NADPH oxidase in the activated state.
Nature, 627, 2024
3BWH
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BU of 3bwh by Molmil
Atomic resolution structure of cucurmosin, a novel type 1 RIP from the sarcocarp of Cucurbita moschata
Descriptor: 1,2-ETHANEDIOL, PHOSPHATE ION, beta-D-xylopyranose-(1-2)-[alpha-D-mannopyranose-(1-3)][alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Chen, L.
Deposit date:2008-01-09
Release date:2008-10-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1 Å)
Cite:Atomic resolution structure of cucurmosin, a novel type 1 ribosome-inactivating protein from the sarcocarp of Cucurbita moschata.
J.Struct.Biol., 164, 2008
3HI1
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BU of 3hi1 by Molmil
Structure of HIV-1 gp120 (core with V3) in Complex with CD4-Binding-Site Antibody F105
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, F105 Heavy Chain, F105 Light Chain, ...
Authors:Kwon, Y.D, Chen, L, Zhou, T, Wu, X, O'Dell, S, Cavacini, L, Hessell, A.J, Pancera, M, Tang, M, Xu, L, Yang, Z, Zhang, M.-Y, Arthos, J, Burton, D.R, Dimitrov, D, Nabel, G.J, Posner, M, Sodroski, J, Wyatt, R, Mascola, J.R, Kwong, P.D.
Deposit date:2009-05-18
Release date:2009-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120.
Science, 326, 2009
8GZ3
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BU of 8gz3 by Molmil
Structure of human phagocyte NADPH oxidase in the resting state
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 7D5 Fab heavy chain, ...
Authors:Chen, L, Liu, R.
Deposit date:2022-09-24
Release date:2022-12-21
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of human phagocyte NADPH oxidase in the resting state.
Elife, 11, 2022
2HJD
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BU of 2hjd by Molmil
Crystal structure of a second quorum sensing antiactivator TraM2 from A. tumefaciens strain A6
Descriptor: Quorum-sensing antiactivator
Authors:Chen, L.
Deposit date:2006-06-30
Release date:2006-10-31
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure and Mechanism of TraM2, a Second Quorum-Sensing Antiactivator of Agrobacterium tumefaciens Strain A6.
J.Bacteriol., 188, 2006
7VLR
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BU of 7vlr by Molmil
Structure of SUR2B in complex with Mg-ATP/ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL HEMISUCCINATE, ...
Authors:Chen, L, Ding, D.
Deposit date:2021-10-05
Release date:2022-05-18
Last modified:2022-12-14
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural identification of vasodilator binding sites on the SUR2 subunit.
Nat Commun, 13, 2022
7VLT
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BU of 7vlt by Molmil
Structure of SUR2B in complex with Mg-ATP/ADP and levcromakalim
Descriptor: (3S,4R)-2,2-dimethyl-3-oxidanyl-4-(2-oxidanylidenepyrrolidin-1-yl)-3,4-dihydrochromene-6-carbonitrile, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Chen, L, Ding, D.
Deposit date:2021-10-05
Release date:2022-05-18
Last modified:2022-12-14
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural identification of vasodilator binding sites on the SUR2 subunit.
Nat Commun, 13, 2022
7VLS
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BU of 7vls by Molmil
Structure of SUR2B in complex with MgATP/ADP and P1075
Descriptor: 1-cyano-2-(2-methylbutan-2-yl)-3-pyridin-3-yl-guanidine, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Chen, L, Ding, D.
Deposit date:2021-10-05
Release date:2022-05-18
Last modified:2022-12-14
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural identification of vasodilator binding sites on the SUR2 subunit.
Nat Commun, 13, 2022
7VLU
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BU of 7vlu by Molmil
Structure of SUR2A in complex with Mg-ATP/ADP and P1075
Descriptor: 1-cyano-2-(2-methylbutan-2-yl)-3-pyridin-3-yl-guanidine, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Chen, L, Ding, D.
Deposit date:2021-10-05
Release date:2022-05-18
Last modified:2022-12-14
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural identification of vasodilator binding sites on the SUR2 subunit.
Nat Commun, 13, 2022
1TQE
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BU of 1tqe by Molmil
Mechanism of recruitment of class II histone deacetylases by myocyte enhancer factor-2
Descriptor: Histone deacetylase 9, MEF2 binding site of nur77 promoter, Myocyte-specific enhancer factor 2B
Authors:Chen, L, Han, A, He, J, Wu, Y, Liu, J.O.
Deposit date:2004-06-17
Release date:2004-12-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mechanism of Recruitment of Class II Histone Deacetylases by Myocyte Enhancer Factor-2.
J.Mol.Biol., 345, 2005
7VSI
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BU of 7vsi by Molmil
Structure of human SGLT2-MAP17 complex bound with empagliflozin
Descriptor: (2S,3R,4R,5S,6R)-2-[4-chloranyl-3-[[4-[(3S)-oxolan-3-yl]oxyphenyl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol, PALMITIC ACID, PDZK1-interacting protein 1, ...
Authors:Chen, L, Niu, Y, Liu, R.
Deposit date:2021-10-26
Release date:2021-12-15
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Structural basis of inhibition of the human SGLT2-MAP17 glucose transporter.
Nature, 601, 2022
4U1W
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BU of 4u1w by Molmil
Full length GluA2-kainate-(R,R)-2b complex crystal form A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 2, ...
Authors:Chen, L, Gouaux, E.
Deposit date:2014-07-16
Release date:2014-08-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
4U1X
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BU of 4u1x by Molmil
Full length GluA2-kainate-(R,R)-2b complex crystal form B
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, ...
Authors:Chen, L, Gouaux, E.
Deposit date:2014-07-16
Release date:2014-08-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.301 Å)
Cite:Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
6WC5
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BU of 6wc5 by Molmil
Crystal Structure of a Ternary MEF2B/NKX2-5/myocardin enhancer DNA Complex
Descriptor: Homeobox protein Nkx-2.5, Myocardin enhancer DNA, Myocyte-specific enhancer factor 2B
Authors:Chen, L, Lei, X.
Deposit date:2020-03-29
Release date:2020-07-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structures of Ternary Complexes of MEF2 and NKX2-5 Bound to DNA Reveal a Disease Related Protein-Protein Interaction Interface.
J.Mol.Biol., 432, 2020
4U1Z
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BU of 4u1z by Molmil
GluA2flip sLBD complexed with kainate and (R,R)-2b crystal form D
Descriptor: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 2,Glutamate receptor 2, N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dipropane-2-sulfonamide
Authors:Chen, L, Gouaux, E.
Deposit date:2014-07-16
Release date:2014-08-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9401 Å)
Cite:Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
4U21
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BU of 4u21 by Molmil
GluA2flip sLBD complexed with FW and (R,R)-2b crystal form E
Descriptor: 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, Glutamate receptor 2,Glutamate receptor 2, N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dipropane-2-sulfonamide
Authors:Chen, L, Gouaux, E.
Deposit date:2014-07-16
Release date:2014-08-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.3908 Å)
Cite:Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014

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