4ZRY
 
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1QX2
 | | X-ray Structure of Calcium-loaded Calbindomodulin (A Calbindin D9k Re-engineered to Undergo a Conformational Opening) at 1.44 A Resolution | | 分子名称: | CALCIUM ION, Vitamin D-dependent calcium-binding protein, intestinal, ... | | 著者 | Bunick, C.G, Nelson, M.R, Mangahas, S, Mizoue, L.S, Bunick, G.J, Chazin, W.J. | | 登録日 | 2003-09-04 | | 公開日 | 2004-05-25 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | | 主引用文献 | Designing Sequence to Control Protein Function in an EF-Hand Protein
J.Am.Chem.Soc., 126, 2004
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4PCW
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8CWO
 | | Cutibacterium acnes 30S ribosomal subunit with Sarecycline bound, body domain only in the local refined map | | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | | 著者 | Lomakin, I.B, Devarkar, S.C, Bunick, C.G. | | 登録日 | 2022-05-19 | | 公開日 | 2023-03-15 | | 最終更新日 | 2023-04-19 | | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | | 主引用文献 | Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism.
Nucleic Acids Res., 51, 2023
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8CVO
 | | Cutibacterium acnes 30S ribosomal subunit with Sarecycline bound, head domain only in the local refined map | | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S13, ... | | 著者 | Lomakin, I.B, Devarkar, S.C, Bunick, C.G. | | 登録日 | 2022-05-18 | | 公開日 | 2023-03-15 | | 最終更新日 | 2023-04-19 | | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | | 主引用文献 | Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism.
Nucleic Acids Res., 51, 2023
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8CVM
 | | Cutibacterium acnes 50S ribosomal subunit with P-site tRNA and Sarecycline bound in the local refined map | | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | 著者 | Lomakin, I.B, Devarkar, S.C, Bunick, C.G. | | 登録日 | 2022-05-18 | | 公開日 | 2023-03-15 | | 最終更新日 | 2023-04-19 | | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | | 主引用文献 | Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism.
Nucleic Acids Res., 51, 2023
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8CRX
 | | Cutibacterium acnes 70S ribosome with mRNA, P-site tRNA and Sarecycline bound | | 分子名称: | 23S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | 著者 | Lomakin, I.B, Devarkar, S.C, Bunick, C.G. | | 登録日 | 2022-05-12 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-04-19 | | 実験手法 | ELECTRON MICROSCOPY (2.78 Å) | | 主引用文献 | Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism.
Nucleic Acids Res., 51, 2023
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2AMI
 | | Solution Structure Of The Calcium-loaded N-Terminal Sensor Domain Of Centrin | | 分子名称: | Caltractin | | 著者 | Hu, H.T, Fagan, P.A, Bunick, C.G, Sheehan, J.H, Chazin, W.J. | | 登録日 | 2005-08-09 | | 公開日 | 2005-08-23 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the N-terminal calcium sensor domain of centrin reveals the biochemical basis for domain-specific function.
J.Biol.Chem., 281, 2006
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6UUI
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6E2J
 | | Crystal structure of the heterocomplex between human keratin 1 coil 1B containing S233L mutation and wild-type human keratin 10 coil 1B | | 分子名称: | Keratin, type I cytoskeletal 10, type II cytoskeletal 1, ... | | 著者 | Eldirany, S.A, Lomakin, I.B, Bunick, C.G. | | 登録日 | 2018-07-11 | | 公開日 | 2019-05-15 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.386 Å) | | 主引用文献 | Human keratin 1/10-1B tetramer structures reveal a knob-pocket mechanism in intermediate filament assembly.
Embo J., 38, 2019
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6EC0
 | | Crystal structure of the wild-type heterocomplex between coil 1B domains of human intermediate filament proteins keratin 1 (KRT1) and keratin 10 (KRT10) | | 分子名称: | CADMIUM ION, COBALT (II) ION, Keratin 1, ... | | 著者 | Eldirany, S.A, Lomakin, I.B, Bunick, C.G. | | 登録日 | 2018-08-07 | | 公開日 | 2019-05-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.983 Å) | | 主引用文献 | Human keratin 1/10-1B tetramer structures reveal a knob-pocket mechanism in intermediate filament assembly.
Embo J., 38, 2019
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6XQD
 | | Crystal structure of the Thermus thermophilus 70S ribosome in complex with sarecycline, UUC-mRNA, and deacylated P-site tRNA at 2.80A resolution | | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Batool, Z, Lomakin, I.B, Bunick, C.G, Polikanov, Y.S. | | 登録日 | 2020-07-09 | | 公開日 | 2020-08-05 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Sarecycline interferes with tRNA accommodation and tethers mRNA to the 70S ribosome.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6XQE
 | | Crystal structure of the Thermus thermophilus 70S ribosome in complex with sarecycline, UAA-mRNA, and deacylated P-site tRNA at 3.00A resolution | | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Batool, Z, Lomakin, I.B, Bunick, C.G, Polikanov, Y.S. | | 登録日 | 2020-07-09 | | 公開日 | 2020-08-05 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Sarecycline interferes with tRNA accommodation and tethers mRNA to the 70S ribosome.
Proc.Natl.Acad.Sci.USA, 117, 2020
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8RUU
 | | Fabs derived from bimekizumab in complex with IL-17F | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoblobulin heavy chain, Immunoblobulin light chain, ... | | 著者 | Adams, R, Lawson, A.D.G. | | 登録日 | 2024-01-31 | | 公開日 | 2024-04-24 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Crystal Structure of Bimekizumab Fab Fragment in Complex with IL-17F Provides Molecular Basis for Dual IL-17A and IL-17F Inhibition.
J Invest Dermatol., 2024
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