6UUI
Crystal structure of the heterocomplex between coil 2B domains of wild-type keratin 1 (KRT1) and keratin 10 (KRT10) containing mutation Cys401Ala
Summary for 6UUI
Entry DOI | 10.2210/pdb6uui/pdb |
Related | 4ZRY |
Descriptor | Keratin, type II cytoskeletal 1, Keratin, type I cytoskeletal 10, octyl beta-D-glucopyranoside, ... (5 entities in total) |
Functional Keywords | intermediate filament, cytoskeleton, skin, coiled-coil, protein fibril |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 28337.38 |
Authors | Lomakin, I.B.,Bunick, C.G. (deposition date: 2019-10-30, release date: 2019-11-13, Last modification date: 2023-10-11) |
Primary citation | Lomakin, I.B.,Hinbest, A.J.,Ho, M.,Eldirany, S.A.,Bunick, C.G. Crystal Structure of Keratin 1/10(C401A) 2B Heterodimer Demonstrates a Proclivity for the C-Terminus of Helix 2B to Form Higher Order Molecular Contacts. Yale J Biol Med, 93:3-17, 2020 Cited by PubMed: 32226330PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.069 Å) |
Structure validation
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