6UUI
Crystal structure of the heterocomplex between coil 2B domains of wild-type keratin 1 (KRT1) and keratin 10 (KRT10) containing mutation Cys401Ala
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | Keratin, type II cytoskeletal 1 | polymer | 120 | 13850.4 | 1 | UniProt (P04264) Pfam (PF00038) | Homo sapiens (Human) | 67 kDa cytokeratin, Cytokeratin-1, CK-1, Hair alpha protein, Keratin-1, K1, Type-II keratin Kb1 |
| 2 | B (X) | Keratin, type I cytoskeletal 10 | polymer | 122 | 14102.5 | 1 | UniProt (P13645) Pfam (PF00038) | Homo sapiens (Human) | Cytokeratin-10,CK-10,Keratin-10,K10 |
| 3 | C (C) | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 1 | Chemie (BOG) | |||
| 4 | D (X) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E, F (C, X) | water | water | 18.0 | 107 | Chemie (HOH) |
Sequence modifications
X: 337 - 456 (UniProt: P13645)
| PDB | External Database | Details |
|---|---|---|
| Gly 335 | - | expression tag |
| Ser 336 | - | expression tag |
| Ala 401 | Cys 401 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27952.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 384.5 | |
| All* | Total formula weight | 28337.4 |
