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2GN5
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BU of 2gn5 by Molmil
REFINED STRUCTURE OF THE GENE 5 DNA BINDING PROTEIN FROM BACTERIOPHAGE FD
Descriptor: GENE V PROTEIN
Authors:Brayer, G.D, McPherson, A.
Deposit date:1986-01-13
Release date:1986-01-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Refined structure of the gene 5 DNA binding protein from bacteriophage fd.
J.Mol.Biol., 169, 1983
2CPU
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BU of 2cpu by Molmil
SUBSITE MAPPING OF THE ACTIVE SITE OF HUMAN PANCREATIC ALPHA-AMYLASE USING SUBSTRATES, THE PHARMACOLOGICAL INHIBITOR ACARBOSE, AND AN ACTIVE SITE VARIANT
Descriptor: ALPHA-AMYLASE, CALCIUM ION, CHLORIDE ION
Authors:Brayer, G.D, Sidhu, G, Maurus, R, Rydberg, E.H, Braun, C, Wang, Y, Nguyen, N.T, Overall, C.M, Withers, S.G.
Deposit date:1999-06-08
Release date:2001-06-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Subsite mapping of the human pancreatic alpha-amylase active site through structural, kinetic, and mutagenesis techniques.
Biochemistry, 39, 2000
3CPU
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BU of 3cpu by Molmil
SUBSITE MAPPING OF THE ACTIVE SITE OF HUMAN PANCREATIC ALPHA-AMYLASE USING SUBSTRATES, THE PHARMACOLOGICAL INHIBITOR ACARBOSE, AND AN ACTIVE SITE VARIANT
Descriptor: CALCIUM ION, CHLORIDE ION, Pancreatic alpha-amylase, ...
Authors:Brayer, G.D, Sidhu, G, Maurus, R, Rydberg, E.H, Braun, C, Wang, Y, Nguyen, N.T, Overall, C.M, Withers, S.G.
Deposit date:1999-06-08
Release date:2001-06-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Subsite mapping of the human pancreatic alpha-amylase active site through structural, kinetic, and mutagenesis techniques.
Biochemistry, 39, 2000
1CPU
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BU of 1cpu by Molmil
SUBSITE MAPPING OF THE ACTIVE SITE OF HUMAN PANCREATIC ALPHA-AMYLASE USING SUBSTRATES, THE PHARMACOLOGICAL INHIBITOR ACARBOSE, AND AN ACTIVE SITE VARIANT
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-amino-4,6-dideoxy-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 5-HYDROXYMETHYL-CHONDURITOL, ...
Authors:Brayer, G.D, Sidhu, G, Maurus, R, Rydberg, E.H, Braun, C, Wang, Y, Nguyen, N.T, Overall, C.M, Withers, S.G.
Deposit date:1999-06-07
Release date:1999-06-14
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Subsite mapping of the human pancreatic alpha-amylase active site through structural, kinetic, and mutagenesis techniques.
Biochemistry, 39, 2000
1HNY
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BU of 1hny by Molmil
The structure of human pancreatic alpha-amylase at 1.8 angstroms resolution and comparisons with related enzymes
Descriptor: CALCIUM ION, CHLORIDE ION, HUMAN PANCREATIC ALPHA-AMYLASE
Authors:Luo, Y, Brayer, G.D.
Deposit date:1995-06-28
Release date:1996-03-08
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure of human pancreatic alpha-amylase at 1.8 A resolution and comparisons with related enzymes.
Protein Sci., 4, 1995
2YCC
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BU of 2ycc by Molmil
OXIDATION STATE-DEPENDENT CONFORMATIONAL CHANGES IN CYTOCHROME C
Descriptor: CYTOCHROME C, HEME C, SULFATE ION
Authors:Berghuis, A.M, Brayer, G.D.
Deposit date:1991-01-29
Release date:1992-07-15
Last modified:2021-03-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Oxidation state-dependent conformational changes in cytochrome c.
J.Mol.Biol., 223, 1992
2ALP
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BU of 2alp by Molmil
REFINED STRUCTURE OF ALPHA-LYTIC PROTEASE AT 1.7 ANGSTROMS RESOLUTION. ANALYSIS OF HYDROGEN BONDING AND SOLVENT STRUCTURE
Descriptor: ALPHA-LYTIC PROTEASE, SULFATE ION
Authors:Fujinaga, M, Delbaere, L.T.J, Brayer, G.D, James, M.N.G.
Deposit date:1985-03-07
Release date:1985-07-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Refined structure of alpha-lytic protease at 1.7 A resolution. Analysis of hydrogen bonding and solvent structure.
J.Mol.Biol., 184, 1985
4X0N
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BU of 4x0n by Molmil
Porcine pancreatic alpha-amylase in complex with helianthamide, a novel proteinaceous inhibitor
Descriptor: CALCIUM ION, CHLORIDE ION, GLYCEROL, ...
Authors:Williams, L.K, Brayer, G.D.
Deposit date:2014-11-21
Release date:2015-11-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6001 Å)
Cite:Structural Templating and Guided Refolding of the Potent Naturally Occurring Peptide Helianthamide Within the Active Site of Amylase, a Diabetes and Obesity Therapeutic Target
To Be Published
4X9Y
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BU of 4x9y by Molmil
Wild-Type Human Pancreatic Alpha-Amylase at True Atomic Resolution (1.07 A)
Descriptor: CALCIUM ION, CHLORIDE ION, Pancreatic alpha-amylase
Authors:Caner, S, Brayer, G.D.
Deposit date:2014-12-11
Release date:2014-12-31
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.07 Å)
Cite:Wild-Type Human Pancreatic Alpha-Amylase at True Atomic Resolution (1.07 A)
To be published
1AZI
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BU of 1azi by Molmil
MYOGLOBIN (HORSE HEART) RECOMBINANT WILD-TYPE COMPLEXED WITH AZIDE
Descriptor: AZIDE ION, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Maurus, R, Brayer, G.D.
Deposit date:1997-10-11
Release date:1998-02-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and spectroscopic studies of azide complexes of horse heart myoglobin and the His-64-->Thr variant.
Biochem.J., 332, 1998
1BJE
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BU of 1bje by Molmil
H64T VARIANT OF MYOGLOBIN (HORSE HEART) RECOMBINANT WILD-TYPE COMPLEXED WITH AZIDE
Descriptor: AZIDE ION, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Maurus, R, Brayer, G.D.
Deposit date:1997-10-18
Release date:1998-01-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and spectroscopic studies of azide complexes of horse heart myoglobin and the His-64-->Thr variant.
Biochem.J., 332, 1998
4G6B
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BU of 4g6b by Molmil
Three dimensional structure analysis of the type II citrate synthase from e.coli
Descriptor: Citrate synthase, SULFATE ION
Authors:Nguyen, N.T, Maurus, R, Stokell, D.J, Ayed, A, Duckworth, H.W, Brayer, G.D.
Deposit date:2012-07-18
Release date:2013-11-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Comparative Analysis of Folding and Substrate Binding Sites between Regulated Hexameric Type II Citrate Synthases and Unregulated Dimeric Type I Enzymes.
Biochemistry, 40, 2001
6OBX
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BU of 6obx by Molmil
Montbretin A analogue M10-MbA in complex with Human pancreatic alpha-amylase
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Caner, S, Brayer, G.D.
Deposit date:2019-03-21
Release date:2020-02-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Synthesis of montbretin A analogues yields potent competitive inhibitors of human pancreatic alpha-amylase.
Chem Sci, 10, 2019
1CIF
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BU of 1cif by Molmil
STRUCTURAL AND FUNCTIONAL EFFECTS OF MULTIPLE MUTATIONS AT DISTAL SITES IN CYTOCHROME C
Descriptor: CYTOCHROME C, HEME C, SULFATE ION
Authors:Lo, T.P, Brayer, G.D.
Deposit date:1994-09-26
Release date:1995-01-26
Last modified:2021-03-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and functional effects of multiple mutations at distal sites in cytochrome c.
Biochemistry, 34, 1995
1CIG
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BU of 1cig by Molmil
STRUCTURAL AND FUNCTIONAL EFFECTS OF MULTIPLE MUTATIONS AT DISTAL SITES IN CYTOCHROME C
Descriptor: CYTOCHROME C, HEME C, SULFATE ION
Authors:Lo, T.P, Brayer, G.D.
Deposit date:1994-09-26
Release date:1995-01-26
Last modified:2021-03-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and functional effects of multiple mutations at distal sites in cytochrome c.
Biochemistry, 34, 1995
6OCN
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BU of 6ocn by Molmil
Montbretin A analogue M06-MbA in complex with Human pancreatic alpha-amylase
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
Authors:Caner, S, Brayer, G.D.
Deposit date:2019-03-25
Release date:2020-02-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.147 Å)
Cite:Synthesis of montbretin A analogues yields potent competitive inhibitors of human pancreatic alpha-amylase.
Chem Sci, 10, 2019
1CIE
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BU of 1cie by Molmil
STRUCTURAL AND FUNCTIONAL EFFECTS OF MULTIPLE MUTATIONS AT DISTAL SITES IN CYTOCHROME C
Descriptor: CYTOCHROME C, HEME C, SULFATE ION
Authors:Lo, T.P, Brayer, G.D.
Deposit date:1994-09-26
Release date:1995-01-26
Last modified:2021-03-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and functional effects of multiple mutations at distal sites in cytochrome c.
Biochemistry, 34, 1995
1CIH
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BU of 1cih by Molmil
STRUCTURAL AND FUNCTIONAL EFFECTS OF MULTIPLE MUTATIONS AT DISTAL SITES IN CYTOCHROME C
Descriptor: CYTOCHROME C, HEME C, SULFATE ION
Authors:Lo, T.P, Brayer, G.D.
Deposit date:1994-09-26
Release date:1995-01-26
Last modified:2021-03-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and functional effects of multiple mutations at distal sites in cytochrome c.
Biochemistry, 34, 1995
6PXF
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BU of 6pxf by Molmil
Structure of human Cathepsin K with an ectosteric inhibitor at 1.85 Angstrom resolution
Descriptor: 1,6,6-trimethyl-10,11-dioxo-6,7,8,9,10,11-hexahydrophenanthro[1,2-b]furan-2-sulfonic acid, Cathepsin K
Authors:Law, S, Aguda, A.H, Nguyen, N.T, Brayer, G.D, Bromme, D.
Deposit date:2019-07-25
Release date:2020-07-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of human Cathepsin K with an ectosteric inhibitor at 1.85 Angstrom resolution
To Be Published
5KEZ
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BU of 5kez by Molmil
Selective and potent inhibition of the glycosidase human amylase by the short and extremely compact peptide piHA from mRNA display
Descriptor: ACE-DTY-PRO-TYR-SER-CYS-TRP-VAL-ARG-HIS-NH2, CALCIUM ION, CHLORIDE ION, ...
Authors:Caner, S, Brayer, G.D.
Deposit date:2016-06-10
Release date:2017-03-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Rapid Discovery of Potent and Selective Glycosidase-Inhibiting De Novo Peptides.
Cell Chem Biol, 24, 2017
1CRH
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BU of 1crh by Molmil
THE ROLE OF A CONSERVED INTERNAL WATER MOLECULE AND ITS ASSOCIATED HYDROGEN BOND NETWORK IN CYTOCHROME C
Descriptor: CYTOCHROME C, HEME C, SULFATE ION
Authors:Berghuis, A.M, Brayer, G.D.
Deposit date:1993-08-06
Release date:1994-01-31
Last modified:2021-03-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The role of a conserved internal water molecule and its associated hydrogen bond network in cytochrome c.
J.Mol.Biol., 236, 1994
1CRI
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BU of 1cri by Molmil
THE ROLE OF A CONSERVED INTERNAL WATER MOLECULE AND ITS ASSOCIATED HYDROGEN BOND NETWORK IN CYTOCHROME C
Descriptor: CYTOCHROME C, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
Authors:Berghuis, A.M, Brayer, G.D.
Deposit date:1993-08-06
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:The role of a conserved internal water molecule and its associated hydrogen bond network in cytochrome c.
J.Mol.Biol., 236, 1994
1CRG
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BU of 1crg by Molmil
THE ROLE OF A CONSERVED INTERNAL WATER MOLECULE AND ITS ASSOCIATED HYDROGEN BOND NETWORK IN CYTOCHROME C
Descriptor: CYTOCHROME C, HEME C, SULFATE ION
Authors:Berghuis, A.M, Brayer, G.D.
Deposit date:1993-08-06
Release date:1994-01-31
Last modified:2021-03-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:The role of a conserved internal water molecule and its associated hydrogen bond network in cytochrome c.
J.Mol.Biol., 236, 1994
1CRJ
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BU of 1crj by Molmil
THE ROLE OF A CONSERVED INTERNAL WATER MOLECULE AND ITS ASSOCIATED HYDROGEN BOND NETWORK IN CYTOCHROME C
Descriptor: CYTOCHROME C, HEME C, SULFATE ION
Authors:Berghuis, A.M, Brayer, G.D.
Deposit date:1993-08-06
Release date:1994-01-31
Last modified:2021-03-03
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The role of a conserved internal water molecule and its associated hydrogen bond network in cytochrome c.
J.Mol.Biol., 236, 1994
1CSW
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BU of 1csw by Molmil
REPLACEMENTS IN A CONSERVED LEUCINE CLUSTER IN THE HYDROPHOBIC HEME POCKET OF CYTOCHROME C
Descriptor: CYTOCHROME C, HEME C, SULFATE ION
Authors:Lo, T.P, Brayer, G.D.
Deposit date:1994-10-04
Release date:1995-01-26
Last modified:2021-03-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Replacements in a conserved leucine cluster in the hydrophobic heme pocket of cytochrome c.
Protein Sci., 4, 1995

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