6DB2
| X-ray crystal structure of VioC bound to vanadyl ion, L-homoarginine, and succinate | Descriptor: | 1,2-ETHANEDIOL, Alpha-ketoglutarate-dependent L-arginine hydroxylase, L-HOMOARGININE, ... | Authors: | Dunham, N.P, Mitchell, A.J, Boal, A.K. | Deposit date: | 2018-05-02 | Release date: | 2018-05-16 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Two Distinct Mechanisms for C-C Desaturation by Iron(II)- and 2-(Oxo)glutarate-Dependent Oxygenases: Importance of alpha-Heteroatom Assistance. J. Am. Chem. Soc., 140, 2018
|
|
6DQX
| Actinobacillus ureae class Id ribonucleotide reductase alpha subunit | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... | Authors: | McBride, M.J, Palowitch, G.M, Boal, A.K. | Deposit date: | 2018-06-11 | Release date: | 2019-04-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Structures of Class Id Ribonucleotide Reductase Catalytic Subunits Reveal a Minimal Architecture for Deoxynucleotide Biosynthesis. Biochemistry, 58, 2019
|
|
6DAZ
| X-ray crystal structure of VioC bound to Fe(II), 3S-hydroxy-L-homoarginine, and succinate | Descriptor: | (3S)-N~6~-carbamimidoyl-3-hydroxy-L-lysine, Alpha-ketoglutarate-dependent L-arginine hydroxylase, FE (II) ION, ... | Authors: | Dunham, N.P, Mitchell, A.J, Boal, A.K. | Deposit date: | 2018-05-02 | Release date: | 2018-05-16 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Two Distinct Mechanisms for C-C Desaturation by Iron(II)- and 2-(Oxo)glutarate-Dependent Oxygenases: Importance of alpha-Heteroatom Assistance. J. Am. Chem. Soc., 140, 2018
|
|
5V7O
| Crystal Structure of NosK from Streptomyces actuosus | Descriptor: | NosK, SULFATE ION | Authors: | Booker, S.J, Boal, A.K, Grove, T.L, Badding, E.D. | Deposit date: | 2017-03-20 | Release date: | 2017-04-12 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Rerouting the Pathway for the Biosynthesis of the Side Ring System of Nosiheptide: The Roles of NosI, NosJ, and NosK. J. Am. Chem. Soc., 139, 2017
|
|
5UY1
| X-ray crystal structure of apo Halotag | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Haloalkane dehalogenase | Authors: | Dunham, N.P, Boal, A.K. | Deposit date: | 2017-02-23 | Release date: | 2017-03-08 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | The Cation-pi Interaction Enables a Halo-Tag Fluorogenic Probe for Fast No-Wash Live Cell Imaging and Gel-Free Protein Quantification. Biochemistry, 56, 2017
|
|
5UXZ
| |
8DQ4
| |
8DQ3
| |
8DQ5
| |
7RON
| |
7ROO
| |
8E8W
| |
8FNS
| |
8FNR
| |
7TOM
| X-ray crystal structure of glycerol dibiphytanyl glycerol tetraether - macrocyclic archaeol synthase (GDGT-MAS) from Methanocaldococcus jannaschii with bacterial lipid substrate analog, 5'deoxyadenosine, and methionine bound | Descriptor: | 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, 5'-DEOXYADENOSINE, FE (III) ION, ... | Authors: | Lloyd, C.T, Booker, S.J, Boal, A.K. | Deposit date: | 2022-01-24 | Release date: | 2022-08-31 | Last modified: | 2022-09-14 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Discovery, structure and mechanism of a tetraether lipid synthase. Nature, 609, 2022
|
|
7KDY
| Crystal structure of Streptomyces tokunonesis TokK with hydroxycobalamin, 5'-deoxyadenosine, methionine, and (2R)-pantetheinylated carbapenam | Descriptor: | (2R,3R,5R)-3-{[2-({N-[(2R)-2,4-dihydroxy-3,3-dimethylbutanoyl]-beta-alanyl}amino)ethyl]sulfanyl}-7-oxo-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 5'-DEOXYADENOSINE, COBALAMIN, ... | Authors: | Knox, H.L, Booker, S.J, Boal, A.K. | Deposit date: | 2020-10-09 | Release date: | 2022-01-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.939 Å) | Cite: | Structure of a B 12 -dependent radical SAM enzyme in carbapenem biosynthesis. Nature, 602, 2022
|
|
7KDX
| Crystal structure of Streptomyces tokunonesis TokK with hydroxycobalamin, 5'-deoxyadenosine, and methionine | Descriptor: | 1,2-ETHANEDIOL, 5'-DEOXYADENOSINE, CHLORIDE ION, ... | Authors: | Knox, H.L, Booker, S.J, Boal, A.K. | Deposit date: | 2020-10-09 | Release date: | 2022-01-12 | Last modified: | 2022-02-23 | Method: | X-RAY DIFFRACTION (1.791 Å) | Cite: | Structure of a B 12 -dependent radical SAM enzyme in carbapenem biosynthesis. Nature, 602, 2022
|
|
7KPI
| Crystal structure of the SPOP MATH domain | Descriptor: | Speckle-type POZ protein | Authors: | Usher, E.T, Boal, A.K. | Deposit date: | 2020-11-11 | Release date: | 2021-04-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Intrinsically disordered substrates dictate SPOP subnuclear localization and ubiquitination activity. J.Biol.Chem., 296, 2021
|
|
7KPK
| |
7TWA
| Crystal structure of apo BesC from Streptomyces cattleya | Descriptor: | 1,3-BUTANEDIOL, 4-chloro-allylglycine synthase, ACETATE ION, ... | Authors: | Neugebauer, M.E, McBride, M.J, Boal, A.K, Chang, M.C.Y. | Deposit date: | 2022-02-07 | Release date: | 2022-04-13 | Last modified: | 2022-04-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Substrate-Triggered mu-Peroxodiiron(III) Intermediate in the 4-Chloro-l-Lysine-Fragmenting Heme-Oxygenase-like Diiron Oxidase (HDO) BesC: Substrate Dissociation from, and C4 Targeting by, the Intermediate. Biochemistry, 61, 2022
|
|
5IQV
| WelO5 bound to Fe, Cl, 2-oxoglutarate, 12-epifischerindole U, and nitric oxide | Descriptor: | (6aS,9R,10R,10aS)-9-ethyl-10-isocyano-6,6,9-trimethyl-5,6,6a,7,8,9,10,10a-octahydroindeno[2,1-b]indole, 2-OXOGLUTARIC ACID, CHLORIDE ION, ... | Authors: | Mitchell, A.J, Boal, A.K. | Deposit date: | 2016-03-11 | Release date: | 2016-06-29 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for halogenation by iron- and 2-oxo-glutarate-dependent enzyme WelO5. Nat.Chem.Biol., 12, 2016
|
|
5HR6
| X-ray crystal structure of C118A RlmN with cross-linked tRNA purified from Escherichia coli | Descriptor: | 5'-DEOXYADENOSINE, IRON/SULFUR CLUSTER, MAGNESIUM ION, ... | Authors: | Schwalm, E.L, Grove, T.L, Booker, S.J, Boal, A.K. | Deposit date: | 2016-01-22 | Release date: | 2016-04-13 | Last modified: | 2016-04-27 | Method: | X-RAY DIFFRACTION (2.88 Å) | Cite: | Crystallographic capture of a radical S-adenosylmethionine enzyme in the act of modifying tRNA. Science, 352, 2016
|
|
5HR7
| X-ray crystal structure of C118A RlmN from Escherichia coli with cross-linked in vitro transcribed tRNA | Descriptor: | 5'-DEOXYADENOSINE, Dual-specificity RNA methyltransferase RlmN, IRON/SULFUR CLUSTER, ... | Authors: | Schwalm, E.L, Grove, T.L, Booker, S.J, Boal, A.K. | Deposit date: | 2016-01-22 | Release date: | 2016-04-13 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystallographic capture of a radical S-adenosylmethionine enzyme in the act of modifying tRNA. Science, 352, 2016
|
|
5IQT
| WelO5 bound to Fe(II), Cl, 2-oxoglutarate, and 12-epifischerindole U | Descriptor: | (6aS,9R,10R,10aS)-9-ethyl-10-isocyano-6,6,9-trimethyl-5,6,6a,7,8,9,10,10a-octahydroindeno[2,1-b]indole, 2-OXOGLUTARIC ACID, CHLORIDE ION, ... | Authors: | Mitchell, A.J, Boal, A.K. | Deposit date: | 2016-03-11 | Release date: | 2016-06-29 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for halogenation by iron- and 2-oxo-glutarate-dependent enzyme WelO5. Nat.Chem.Biol., 12, 2016
|
|
6MP9
| X-ray crystal structure of VioC bound to Fe(II), 2-oxo-5-guanidinopentanoic acid, and succinate | Descriptor: | 5-carbamimidamido-2-oxopentanoic acid, Alpha-ketoglutarate-dependent L-arginine hydroxylase, FE (II) ION, ... | Authors: | Dunham, N.P, Boal, A.K. | Deposit date: | 2018-10-05 | Release date: | 2018-11-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | alpha-Amine Desaturation of d-Arginine by the Iron(II)- and 2-(Oxo)glutarate-Dependent l-Arginine 3-Hydroxylase, VioC. Biochemistry, 57, 2018
|
|