4ADW
| CRYSTAL STRUCTURE OF LEISHMANIA INFANTUM TRYPANOTHIONE REDUCTASE IN COMPLEX WITH NADPH AND TRYPANOTHIONE | 分子名称: | BIS(GAMMA-GLUTAMYL-CYSTEINYL-GLYCINYL)SPERMIDINE, FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Baiocco, P, Ilari, A, Colotti, G, Malatesta, F, Fiorillo, A. | 登録日 | 2012-01-04 | 公開日 | 2013-01-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.61 Å) | 主引用文献 | Inhibition of Leishmania Infantum Trypanothione Reductase by Azole-Based Compounds: A Comparative Analysis with its Physiological Substrate by X-Ray Crystallography. Chemmedchem, 8, 2013
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4APN
| Structure of TR from Leishmania infantum in complex with a diarylpirrole-based inhibitor | 分子名称: | 4-[[1-(4-ethylphenyl)-2-methyl-5-(4-methylsulfanylphenyl)pyrrol-3-yl]methyl]thiomorpholine, FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Baiocco, P, Ilari, A, Colotti, G, Biava, M. | 登録日 | 2012-04-04 | 公開日 | 2013-04-17 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Inhibition of Leishmania Infantum Trypanothione Reductase by Azole-Based Compounds: A Comparative Analysis with its Physiological Substrate by X-Ray Crystallography. Chemmedchem, 8, 2013
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2JK6
| Structure of Trypanothione Reductase from Leishmania infantum | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, TRYPANOTHIONE REDUCTASE | 著者 | Baiocco, P, Colotti, G, Franceschini, S, Ilari, A. | 登録日 | 2008-08-21 | 公開日 | 2009-04-28 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Molecular Basis of Antimony Treatment in Leishmaniasis. J.Med.Chem., 52, 2009
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2W0H
| X ray structure of Leishmania infantum Trypanothione reductase in complex with antimony and NADPH | 分子名称: | ANTIMONY (III) ION, FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Baiocco, P, Colotti, G, Franceschini, S, Ilari, A. | 登録日 | 2008-08-18 | 公開日 | 2009-04-28 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Molecular Basis of Antimony Treatment in Leishmaniasis. J.Med.Chem., 52, 2009
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2X50
| Crystal structure of Trypanothione reductase from Leishmania infantum in complex with NADPH and silver | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SILVER ION, ... | 著者 | Baiocco, P, Ilari, A, Colotti, G. | 登録日 | 2010-02-03 | 公開日 | 2011-01-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Inhibitory Effect of Silver Nanoparticles on Trypanothione Reductase Activity and Leishmania Infantum Proliferation Acs Med.Chem.Lett., 2, 2011
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2C80
| Structure of Sh28GST in complex with S-hexyl Glutathione | 分子名称: | GLUTATHIONE S-TRANSFERASE 28 KDA, S-HEXYLGLUTATHIONE, TETRAETHYLENE GLYCOL | 著者 | Baiocco, P, Gourlay, L.J, Angelucci, F, Bellelli, A, Brunori, M, Miele, A.E. | 登録日 | 2005-11-30 | 公開日 | 2006-06-21 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Probing the Mechanism of Gsh Activation in Schistosoma Haematobium Glutathione-S-Transferase by Site-Directed Mutagenesis and X-Ray Crystallography. J.Mol.Biol., 360, 2006
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2CAI
| Structure of Glutathione-S-Transferase mutant, R21L, from Schistosoma Haematobium | 分子名称: | BETA-MERCAPTOETHANOL, GLUTATHIONE S-TRANSFERASE 28 KDA, SULFATE ION, ... | 著者 | Baiocco, P, Gourlay, L.J, Angelucci, F, Bellelli, A, Brunori, M, Miele, A.E. | 登録日 | 2005-12-21 | 公開日 | 2006-06-21 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Probing the Mechanism of Gsh Activation in Schistosoma Haematobium Glutathione-S-Transferase by Site-Directed Mutagenesis and X-Ray Crystallography. J.Mol.Biol., 360, 2006
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2C8U
| Structure of R21Q mutant of Sh28GST | 分子名称: | BETA-MERCAPTOETHANOL, GLUTATHIONE S-TRANSFERASE 28 KDA, SULFATE ION | 著者 | Baiocco, P, Gourlay, L.J, Angelucci, F, Bellelli, A, Miele, A.E, Brunori, M. | 登録日 | 2005-12-07 | 公開日 | 2006-06-21 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Probing the Mechanism of Gsh Activation in Schistosoma Haematobium Glutathione-S-Transferase by Site-Directed Mutagenesis and X-Ray Crystallography. J.Mol.Biol., 360, 2006
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2CA8
| Structure of Sh28GST in complex with GSH at pH 6.0 | 分子名称: | GLUTATHIONE, GLUTATHIONE S-TRANSFERASE 28 KDA, TETRAETHYLENE GLYCOL | 著者 | Baiocco, P, Gourlay, L.J, Angelucci, F, Bellelli, A, Miele, A.E, Brunori, M. | 登録日 | 2005-12-20 | 公開日 | 2006-06-26 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Probing the Mechanism of Gsh Activation in Schistosoma Haematobium Glutathione-S-Transferase by Site-Directed Mutagenesis and X-Ray Crystallography. J.Mol.Biol., 360, 2006
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2CAQ
| Structure of R21L mutant of Sh28GST in complex with GSH | 分子名称: | BETA-MERCAPTOETHANOL, GLUTATHIONE, GLUTATHIONE S-TRANSFERASE 28 KDA, ... | 著者 | Baiocco, P, Gourlay, L.J, Angelucci, F, Bellelli, A, Miele, A.E, Brunori, M. | 登録日 | 2005-12-22 | 公開日 | 2006-06-21 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Probing the Mechanism of Gsh Activation in Schistosoma Haematobium Glutathione-S-Transferase by Site-Directed Mutagenesis and X-Ray Crystallography. J.Mol.Biol., 360, 2006
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4UZV
| Structure of a triple mutant of ASV-TfTrHb | 分子名称: | ACETATE ION, HEMOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Baiocco, P, Bonamore, A, Sciamanna, N, Ilari, A, Boechi, L, Boffi, A, Smulevich, G, Feis, A. | 登録日 | 2014-09-09 | 公開日 | 2014-09-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Role of Local Structure and Dynamics of Small Ligand Migration in Proteins: A Study of a Mutated Truncated Hemoprotein from Thermobifida Fusca by Time Resolved Mir Spectroscopy. J.Phys.Chem.B, 118, 2014
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5LS9
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2F8F
| Crystal structure of the Y10F mutant of the gluathione s-transferase from schistosoma haematobium | 分子名称: | GLUTATHIONE, Glutathione S-transferase 28 kDa | 著者 | Gourlay, L.J, Baiocco, P, Angelucci, F, Miele, A.E, Bellelli, A, Brunori, M. | 登録日 | 2005-12-02 | 公開日 | 2006-07-04 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Probing the Mechanism of GSH Activation in Schistosoma haematobium Glutathione-S-transferase by Site-directed Mutagenesis and X-ray Crystallography. J.Mol.Biol., 360, 2006
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5OBB
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5OBA
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2YAU
| X-ray structure of the Leishmania infantum tryopanothione reductase in complex with auranofin | 分子名称: | 2,3,4,6-tetra-O-acetyl-1-thio-beta-D-glucopyranose, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Baiocco, P, Ilari, A, Colotti, G. | 登録日 | 2011-02-24 | 公開日 | 2012-01-11 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | A Gold-Containing Drug Against Parasitic Polyamine Metabolism: The X-Ray Structure of Trypanothione Reductase from Leishmania Infantum in Complex with Auranofin Reveals a Dual Mechanism of Enzyme Inhibition. Amino Acids, 42, 2012
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6GSR
| Single Particle Cryo-EM map of human Transferrin receptor 1 - H-Ferritin complex at 5.5 Angstrom resolution. | 分子名称: | Ferritin heavy chain, Transferrin receptor protein 1 | 著者 | Testi, C, Montemiglio, L.C, Vallone, B, Des Georges, A, Boffi, A, Mancia, F, Baiocco, P. | 登録日 | 2018-06-15 | 公開日 | 2019-03-27 | 最終更新日 | 2019-05-08 | 実験手法 | ELECTRON MICROSCOPY (5.5 Å) | 主引用文献 | Cryo-EM structure of the human ferritin-transferrin receptor 1 complex. Nat Commun, 10, 2019
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6H5I
| Single Particle Cryo-EM map of human Transferrin receptor 1 - H-Ferritin complex. | 分子名称: | Ferritin heavy chain, Transferrin receptor protein 1 | 著者 | Testi, C, Montemiglio, L.C, Vallone, B, Des Georges, A, Boffi, A, Mancia, F, Baiocco, P, Savino, C. | 登録日 | 2018-07-24 | 公開日 | 2019-03-27 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Cryo-EM structure of the human ferritin-transferrin receptor 1 complex. Nat Commun, 10, 2019
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1VYF
| schistosoma mansoni fatty acid binding protein in complex with oleic acid | 分子名称: | 14 KDA FATTY ACID BINDING PROTEIN, OLEIC ACID | 著者 | Angelucci, F, Johnson, K.A, Baiocco, P, Miele, A.E, Bellelli, A. | 登録日 | 2004-04-29 | 公開日 | 2004-09-23 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Schistosoma Mansoni Fatty Acid Binding Protein: Specificity and Functional Control as Revealed by Crystallographic Structure Biochemistry, 43, 2004
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1VYG
| schistosoma mansoni fatty acid binding protein in complex with arachidonic acid | 分子名称: | ARACHIDONIC ACID, FATTY ACID BINDING PROTEIN | 著者 | Angelucci, F, Johnson, K.A, Baiocco, P, Miele, A.E, Bellelli, A. | 登録日 | 2004-04-29 | 公開日 | 2004-09-23 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Schistosoma Mansoni Fatty Acid Binding Protein: Specificity and Functional Control as Revealed by Crystallographic Structure Biochemistry, 43, 2004
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2XWY
| Structure of MK-3281, a Potent Non-Nucleoside Finger-Loop Inhibitor, in complex with the Hepatitis C Virus NS5B Polymerase | 分子名称: | (7R)-14-cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl)amino}-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylic acid, MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE | 著者 | Di Marco, S, Baiocco, P. | 登録日 | 2010-11-06 | 公開日 | 2010-12-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Discovery of (7R)-14-Cyclohexyl-7-{[2-(Dimethylamino)Ethyl] (Methyl)Amino}-7,8-Dihydro-6H-Indolo[1,2-E][1,5] Benzoxazocine -11-Carboxylic Acid (Mk-3281), a Potent and Orally Bioavailable Finger-Loop Inhibitor of the Hepatitis C Virus Ns5B Polymerase J.Med.Chem., 54, 2011
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3S9F
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3TUE
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2CK1
| The structure of oxidised cyclophilin A from s. mansoni | 分子名称: | ACETATE ION, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE E | 著者 | Gourlay, L.J, Angelucci, F, Bellelli, A, Boumis, G, Miele, A.E, Brunori, M. | 登録日 | 2006-04-10 | 公開日 | 2007-05-15 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The Three-Dimensional Structure of Two Redox States of Cyclophilin-A from Schistosoma Mansoni: Evidence for Redox- Regulation of Peptidyl-Prolyl Cis-Trans Isomerase Activity. J.Biol.Chem., 282, 2007
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2CMT
| The structure of reduced cyclophilin A from s. mansoni | 分子名称: | ACETATE ION, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE E | 著者 | Gourlay, L.J, Angelucci, F, Bellelli, A, Boumis, G, Miele, A.E, Brunori, M. | 登録日 | 2006-05-12 | 公開日 | 2007-05-15 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The Three-Dimensional Structure of Two Redox States of Cyclophilin a from Schistosoma Mansoni. Evidence for Redox Regulation of Peptidyl-Prolyl Cis-Trans Isomerase Activity. J.Biol.Chem., 282, 2007
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