2CMT
The structure of reduced cyclophilin A from s. mansoni
Summary for 2CMT
Entry DOI | 10.2210/pdb2cmt/pdb |
Related | 2CK1 |
Descriptor | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE E, ACETATE ION (3 entities in total) |
Functional Keywords | rotamase activity, rotamase, isomerase, rna-binding, cyclosporin, cyclophilin, schistosoma, beta-barrel |
Biological source | SCHISTOSOMA MANSONI (BLOOD FLUKE) |
Cellular location | Cytoplasm (By similarity): Q26548 |
Total number of polymer chains | 1 |
Total formula weight | 19277.14 |
Authors | Gourlay, L.J.,Angelucci, F.,Bellelli, A.,Boumis, G.,Miele, A.E.,Brunori, M. (deposition date: 2006-05-12, release date: 2007-05-15, Last modification date: 2023-12-13) |
Primary citation | Gourlay, L.J.,Angelucci, F.,Baiocco, P.,Boumis, G.,Brunori, M.,Bellelli, A.,Miele, A.E. The Three-Dimensional Structure of Two Redox States of Cyclophilin a from Schistosoma Mansoni. Evidence for Redox Regulation of Peptidyl-Prolyl Cis-Trans Isomerase Activity. J.Biol.Chem., 282:24851-, 2007 Cited by PubMed: 17591771DOI: 10.1074/JBC.M702714200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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