2W0H

X ray structure of Leishmania infantum Trypanothione reductase in complex with antimony and NADPH

Summary for 2W0H

Entry DOI	10.2210/pdb2w0h/pdb
Related	2JK6
Descriptor	TRYPANOTHIONE REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, ANTIMONY (III) ION, ... (6 entities in total)
Functional Keywords	fad, leishamnia, antimonials, flavoprotein, reduced nadph, oxidoreductase, redox-active center, trypanothione metabolism
Biological source	LEISHMANIA INFANTUM
Total number of polymer chains	2
Total formula weight	114012.68
Authors	Baiocco, P.,Colotti, G.,Franceschini, S.,Ilari, A. (deposition date: 2008-08-18, release date: 2009-04-28, Last modification date: 2023-12-13)
Primary citation	Baiocco, P.,Colotti, G.,Franceschini, S.,Ilari, A. Molecular Basis of Antimony Treatment in Leishmaniasis. J.Med.Chem., 52:2603-, 2009 Cited by PubMed: 19317451 DOI: 10.1021/JM900185Q PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation