2X50
Crystal structure of Trypanothione reductase from Leishmania infantum in complex with NADPH and silver
Summary for 2X50
| Entry DOI | 10.2210/pdb2x50/pdb |
| Related | 2JK6 2W0H |
| Descriptor | TRYPANOTHIONE REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (6 entities in total) |
| Functional Keywords | fad, flavoprotein, leishmaniasis, oxidative metabolism, oxidoreductase, redox-active center |
| Biological source | LEISHMANIA INFANTUM |
| Total number of polymer chains | 2 |
| Total formula weight | 113974.31 |
| Authors | Baiocco, P.,Ilari, A.,Colotti, G. (deposition date: 2010-02-03, release date: 2011-01-12, Last modification date: 2023-12-20) |
| Primary citation | Baiocco, P.,Colotti, G.,Ilari, A. Inhibitory Effect of Silver Nanoparticles on Trypanothione Reductase Activity and Leishmania Infantum Proliferation Acs Med.Chem.Lett., 2:230-, 2011 Cited by PubMed: 24900299DOI: 10.1021/ML1002629 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.3 Å) |
Structure validation
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