2CK1
The structure of oxidised cyclophilin A from s. mansoni
Summary for 2CK1
| Entry DOI | 10.2210/pdb2ck1/pdb |
| Descriptor | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE E, ACETATE ION (3 entities in total) |
| Functional Keywords | disulphide bridge, cyclophilin, cyclosporin, rotamase activity, rotamase, isomerase, rna-binding, beta-barrel |
| Biological source | SCHISTOSOMA MANSONI (BLOOD FLUKE) |
| Cellular location | Cytoplasm (By similarity): Q26548 |
| Total number of polymer chains | 1 |
| Total formula weight | 19277.14 |
| Authors | Gourlay, L.J.,Angelucci, F.,Bellelli, A.,Boumis, G.,Miele, A.E.,Brunori, M. (deposition date: 2006-04-10, release date: 2007-05-15, Last modification date: 2023-12-13) |
| Primary citation | Gourlay, L.J.,Angelucci, F.,Baiocco, P.,Boumis, G.,Brunori, M.,Bellelli, A.,Miele, A.E. The Three-Dimensional Structure of Two Redox States of Cyclophilin-A from Schistosoma Mansoni: Evidence for Redox- Regulation of Peptidyl-Prolyl Cis-Trans Isomerase Activity. J.Biol.Chem., 282:24851-, 2007 Cited by PubMed: 17591771DOI: 10.1074/JBC.M702714200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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