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7NP9
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BU of 7np9 by Molmil
Structure of the human CR3 - CD11bCD18 specific nanobody hCR3Nb1
Descriptor: SULFATE ION, hCR3Nb1
Authors:Jensen, R.K, Andersen, G.R.
Deposit date:2021-02-26
Release date:2022-03-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.14 Å)
Cite:Structural insights into the function-modulating effects of nanobody binding to the integrin receptor alpha M beta 2.
J.Biol.Chem., 298, 2022
4X7T
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BU of 4x7t by Molmil
Structure of Omalizumab Fab fragment, crystal form 2
Descriptor: Omalizumab-Fab Heavy chain, Omalizumab-Fab Light chain, SULFATE ION
Authors:Jensen, R.K, Andersen, G.R.
Deposit date:2014-12-09
Release date:2015-03-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the omalizumab Fab
Acta Crystallogr.,Sect.F, 71, 2015
4X7S
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BU of 4x7s by Molmil
Structure of omalizumab Fab fragment crystal form 1
Descriptor: Epididymis luminal protein 214, Ig kappa chain C region
Authors:Jensen, R.K, Andersen, G.R.
Deposit date:2014-12-09
Release date:2015-03-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the omalizumab Fab
Acta Crystallogr.,Sect.F, 71, 2015
5HLO
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BU of 5hlo by Molmil
Crystal structure of calcium and zinc-bound human S100A8 in space group C2221
Descriptor: ACETATE ION, CACODYLATE ION, CALCIUM ION, ...
Authors:Lin, H, Andersen, G.R, Yatime, L.
Deposit date:2016-01-15
Release date:2016-06-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of human S100A8 in complex with zinc and calcium.
Bmc Struct.Biol., 16, 2016
4XW2
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BU of 4xw2 by Molmil
Structural basis for simvastatin competitive antagonism of complement receptor 3
Descriptor: Integrin alpha-M, MAGNESIUM ION, Simvastatin acid
Authors:Bajic, G, Jensen, M.R, Vorup-Jensen, T, Andersen, G.R.
Deposit date:2015-01-28
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Structural Basis for Simvastatin Competitive Antagonism of Complement Receptor 3.
J.Biol.Chem., 291, 2016
6YO6
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BU of 6yo6 by Molmil
Structure of iC3b1
Descriptor: hC3Nb1, iC3b1 alpha chain, iC3b1 beta chain
Authors:Jensen, R.K, Andersen, G.R.
Deposit date:2020-04-14
Release date:2021-02-24
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (6 Å)
Cite:Complement Receptor 3 Forms a Compact High-Affinity Complex with iC3b.
J Immunol., 206, 2021
5HLV
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BU of 5hlv by Molmil
Crystal structure of calcium and zinc-bound human S100A8 in space group P212121
Descriptor: ACETATE ION, CALCIUM ION, CHLORIDE ION, ...
Authors:Lin, H, Andersen, G.R, Yatime, L.
Deposit date:2016-01-15
Release date:2016-06-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of human S100A8 in complex with zinc and calcium.
Bmc Struct.Biol., 16, 2016
4LP4
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BU of 4lp4 by Molmil
Crystal structure of the human RAGE VC1 fragment in space group P62
Descriptor: Advanced glycosylation end product-specific receptor, SODIUM ION
Authors:Yatime, L, Andersen, G.R.
Deposit date:2013-07-15
Release date:2013-10-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into the oligomerization mode of the human receptor for advanced glycation end-products.
Febs J., 280, 2013
4LP5
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BU of 4lp5 by Molmil
Crystal structure of the full-length human RAGE extracellular domain (VC1C2 fragment)
Descriptor: Advanced glycosylation end product-specific receptor
Authors:Yatime, L, Andersen, G.R.
Deposit date:2013-07-15
Release date:2013-10-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural insights into the oligomerization mode of the human receptor for advanced glycation end-products.
Febs J., 280, 2013
4M76
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BU of 4m76 by Molmil
Integrin I domain of complement receptor 3 in complex with C3d
Descriptor: Complement C3, Integrin alpha-M, NICKEL (II) ION
Authors:Bajic, G, Yatime, L, Vorup-Jensen, T, Andersen, G.R.
Deposit date:2013-08-12
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.804 Å)
Cite:Structural insight on the recognition of surface-bound opsonins by the integrin I domain of complement receptor 3.
Proc.Natl.Acad.Sci.USA, 110, 2013
6YSQ
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BU of 6ysq by Molmil
The hC4Nb8 complement inhibitory nanobody in complex with C4b
Descriptor: Complement C4 beta chain, Complement C4 gamma chain, Complement C4-A alpha chain, ...
Authors:Zarantonello, A, Laursen, N.S, Andersen, G.R.
Deposit date:2020-04-23
Release date:2020-06-24
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:An Ultrahigh-Affinity Complement C4b-Specific Nanobody Inhibits In Vivo Assembly of the Classical Pathway Proconvertase.
J Immunol., 205, 2020
6Z6V
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BU of 6z6v by Molmil
Globular head of C1q in complex with the nanobody C1qNb75
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C1q subcomponent subunit A, Complement C1q subcomponent subunit B, ...
Authors:Laursen, N.S, Andersen, G.R.
Deposit date:2020-05-29
Release date:2020-06-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Functional and Structural Characterization of a Potent C1q Inhibitor Targeting the Classical Pathway of the Complement System.
Front Immunol, 11, 2020
5I5K
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BU of 5i5k by Molmil
Structure of complement C5 in complex with eculizumab
Descriptor: Complement C5, Eculizumab heavy chain (variable domain), Eculizumab light chain (variable domain), ...
Authors:Schatz-Jakobsen, J.A, Andersen, G.R.
Deposit date:2016-02-15
Release date:2016-03-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Structural Basis for Eculizumab-Mediated Inhibition of the Complement Terminal Pathway.
J Immunol., 197, 2016
4YBH
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BU of 4ybh by Molmil
Crystal structure of the human RAGE ectodomain (VC1C2 fragment) in complex with human S100A6
Descriptor: ACETATE ION, Advanced glycosylation end product-specific receptor, CALCIUM ION, ...
Authors:Yatime, L, Andersen, G.R.
Deposit date:2015-02-18
Release date:2016-03-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Structure of the RAGE:S100A6 Complex Reveals a Unique Mode of Homodimerization for S100 Proteins.
Structure, 24, 2016
5I8Q
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BU of 5i8q by Molmil
S. cerevisiae Prp43 in complex with RNA and ADPNP
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43, ...
Authors:He, Y, Nielsen, K.H, Andersen, G.R.
Deposit date:2016-02-19
Release date:2017-02-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Structure of the DEAH/RHA ATPase Prp43p bound to RNA implicates a pair of hairpins and motif Va in translocation along RNA.
RNA, 23, 2017
5NQW
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BU of 5nqw by Molmil
IgE-Fc in complex with single domain antibody 026
Descriptor: 026, GLYCEROL, Immunoglobulin heavy constant epsilon, ...
Authors:Laursen, N.S, Jabs, F, Spillner, E, Andersen, G.R.
Deposit date:2017-04-21
Release date:2018-01-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Trapping IgE in a closed conformation by mimicking CD23 binding prevents and disrupts Fc epsilon RI interaction.
Nat Commun, 9, 2018
4OF5
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BU of 4of5 by Molmil
Refinement of RAGE-DNA complex in 3S59 without DNA
Descriptor: Advanced glycosylation end product-specific receptor
Authors:Yatime, L, Andersen, G.R.
Deposit date:2014-01-14
Release date:2014-04-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.803 Å)
Cite:The specificity of DNA recognition by the RAGE receptor.
J.Exp.Med., 211, 2014
4OFV
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BU of 4ofv by Molmil
Refinement of RAGE-DNA complex in 3S58 without DNA
Descriptor: Advanced glycosylation end product-specific receptor
Authors:Yatime, L, Andersen, G.R.
Deposit date:2014-01-15
Release date:2014-04-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The specificity of DNA recognition by the RAGE receptor.
J.Exp.Med., 211, 2014
4P3B
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BU of 4p3b by Molmil
Crystal structure of the mouse C5a-desArg anaphylatoxin
Descriptor: Complement C5, FORMIC ACID
Authors:Yatime, L, Schatz-Jakobsen, J.A, Andersen, G.R.
Deposit date:2014-03-06
Release date:2014-06-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and functional characterization of human and murine C5a anaphylatoxins.
Acta Crystallogr. D Biol. Crystallogr., 70, 2014
4P3A
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BU of 4p3a by Molmil
Crystal structure of the mouse C5a anaphylatoxin
Descriptor: Complement C5, FORMIC ACID
Authors:Yatime, L, Schatz-Jakobsen, J.A, Andersen, G.R.
Deposit date:2014-03-06
Release date:2014-06-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural and functional characterization of human and murine C5a anaphylatoxins.
Acta Crystallogr. D Biol. Crystallogr., 70, 2014
4P39
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BU of 4p39 by Molmil
Crystal structure of the human C5aR antagonist C5a-A8
Descriptor: Complement C5
Authors:Yatime, L, Schatz-Jakobsen, J.A, Larsen, C, Andersen, G.R.
Deposit date:2014-03-06
Release date:2014-06-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Structural and functional characterization of human and murine C5a anaphylatoxins.
Acta Crystallogr. D Biol. Crystallogr., 70, 2014
4P2Y
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BU of 4p2y by Molmil
Crystal structure of the human RAGE ectodomain (fragment VC1C2) in complex with mouse S100A6
Descriptor: ACETATE ION, Advanced glycosylation end product-specific receptor, CALCIUM ION, ...
Authors:Yatime, L, Andersen, G.R.
Deposit date:2014-03-05
Release date:2015-03-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Structure of the RAGE:S100A6 Complex Reveals a Unique Mode of Homodimerization for S100 Proteins.
Structure, 2016
1NHY
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BU of 1nhy by Molmil
Crystal Structure of the GST-like Domain of Elongation Factor 1-gamma from Saccharomyces cerevisiae.
Descriptor: Elongation factor 1-gamma 1, SULFATE ION
Authors:Jeppesen, M.G, Ortiz, P, Kinzy, T.G, Andersen, G.R, Nyborg, J.
Deposit date:2002-12-20
Release date:2003-01-14
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Crystal Structure of the Glutathione S-Transferase-like Domain of Elongation Factor 1B{gamma} from Saccharomyces cerevisiae.
J.Biol.Chem., 278, 2003
1PBU
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BU of 1pbu by Molmil
Solution structure of the C-terminal domain of the human eEF1Bgamma subunit
Descriptor: Elongation factor 1-gamma
Authors:Vanwetswinkel, S, Kriek, J, Andersen, G.R, Guntert, P, Dijk, J, Canters, G.W, Siegal, G.
Deposit date:2003-05-15
Release date:2003-07-15
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:1H, (15)N and (13)C resonance assignments of the highly conserved 19 kDa C-terminal domain from human Elongation Factor 1Bgamma.
J.Biomol.Nmr, 26, 2003
1PAQ
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BU of 1paq by Molmil
CRYSTAL STRUCTURE OF THE CATALYTIC FRAGMENT OF EUKARYOTIC INITIATION FACTOR 2B EPSILON
Descriptor: Translation initiation factor eIF-2B epsilon subunit
Authors:Boesen, T, Andersen, G.R, Pavitt, G.D.
Deposit date:2003-05-14
Release date:2004-02-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the catalytic fragment of translation initiation factor 2B and identification of a critically important catalytic residue.
J.Biol.Chem., 279, 2004

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