6RIH
 
 | | Crystal structure of PHGDH in complex with compound 9 | | Descriptor: | D-3-phosphoglycerate dehydrogenase, SULFATE ION, ~{N}-cyclopropyl-2-methyl-5-phenyl-pyrazole-3-carboxamide | | Authors: | Bader, G, Wolkerstorfer, B, Zoephel, A. | | Deposit date: | 2019-04-24 | | Release date: | 2019-08-07 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Intracellular Trapping of the Selective Phosphoglycerate Dehydrogenase (PHGDH) InhibitorBI-4924Disrupts Serine Biosynthesis.
J.Med.Chem., 62, 2019
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6RJ2
 | | Crystal structure of PHGDH in complex with compound 40 | | Descriptor: | D-3-phosphoglycerate dehydrogenase, SULFATE ION, ~{N}-[(1~{R})-1-[4-(ethanoylsulfamoyl)phenyl]ethyl]-2-methyl-5-phenyl-pyrazole-3-carboxamide | | Authors: | Bader, G, Wolkerstorfer, B, Zoephel, A. | | Deposit date: | 2019-04-26 | | Release date: | 2019-08-07 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Intracellular Trapping of the Selective Phosphoglycerate Dehydrogenase (PHGDH) InhibitorBI-4924Disrupts Serine Biosynthesis.
J.Med.Chem., 62, 2019
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7AGG
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7AGF
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6GFJ
 | | Structure of RIP2 CARD domain fused to crystallisable MBP tag | | Descriptor: | Sugar ABC transporter substrate-binding protein,Receptor-interacting serine/threonine-protein kinase 2, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | Authors: | Pellegrini, E, Cusack, S. | | Deposit date: | 2018-04-30 | | Release date: | 2019-03-13 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | RIP2 filament formation is required for NOD2 dependent NF-kappa B signalling.
Nat Commun, 9, 2018
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5FHK
 | | Regulatory domain of AphB in Vibrio vulnificus | | Descriptor: | LysR family transcriptional regulator | | Authors: | Song, S, Ha, N.-C. | | Deposit date: | 2015-12-22 | | Release date: | 2017-01-11 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.905 Å) | | Cite: | Crystal Structure of the Regulatory Domain of AphB from Vibrio vulnificus, a Virulence Gene Regulator
Mol. Cells, 40, 2017
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5LYE
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5X0N
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5X0O
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6Y1Z
 | | Mouse serotonin 5HT3 receptor in complex with palonosetron | | Descriptor: | (3~{a}~{S})-2-[(3~{S})-1-azabicyclo[2.2.2]octan-3-yl]-3~{a},4,5,6-tetrahydro-3~{H}-benzo[de]isoquinolin-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Zarkadas, E, Perot, J, Nury, H. | | Deposit date: | 2020-02-14 | | Release date: | 2020-03-04 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (2.82 Å) | | Cite: | The Binding of Palonosetron and Other Antiemetic Drugs to the Serotonin 5-HT3 Receptor.
Structure, 28, 2020
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6RLP
 | | Cryo-EM reconstruction of TMV coat protein | | Descriptor: | Capsid protein, RNA (5'-R(P*GP*AP*A)-3') | | Authors: | Kandiah, E, Effantin, G. | | Deposit date: | 2019-05-02 | | Release date: | 2022-11-23 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (2.3 Å) | | Cite: | CM01: a facility for cryo-electron microscopy at the European Synchrotron.
Acta Crystallogr D Struct Biol, 75, 2019
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5MKC
 | | Crystal structure of the RrgA Jo.In complex | | Descriptor: | CALCIUM ION, Cell wall surface anchor family protein (Jo),Cell wall surface anchor family protein (In), NICKEL (II) ION, ... | | Authors: | Bonnet, J, Cartannaz, J, Tourcier, G, Contreras-Martel, C, Kleman, J.P, Fenel, D, Schoehn, G, Morlot, C, Vernet, T, Di Guilmi, A.M. | | Deposit date: | 2016-12-03 | | Release date: | 2017-03-15 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Autocatalytic association of proteins by covalent bond formation: a Bio Molecular Welding toolbox derived from a bacterial adhesin.
Sci Rep, 7, 2017
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8IWG
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8IWQ
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8IX9
 | | Pseudomoans Aerugiona Wildtype Ketopantoate Reductase with NADPH | | Descriptor: | 2-dehydropantoate 2-reductase, FORMIC ACID, GLYCEROL, ... | | Authors: | Choudhury, G.B, Datta, S. | | Deposit date: | 2023-03-31 | | Release date: | 2024-04-03 | | Last modified: | 2024-07-31 | | Method: | X-RAY DIFFRACTION (2.198 Å) | | Cite: | Implication of Molecular Constraints Facilitating the Functional Evolution of Pseudomonas aeruginosa KPR2 into a Versatile alpha-Keto-Acid Reductase.
Biochemistry, 63, 2024
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8IXM
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8IXH
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6ZLV
 | | MreC | | Descriptor: | Rod shape-determining protein MreC | | Authors: | Estrozi, L.F, Contreras-Martel, C. | | Deposit date: | 2020-07-01 | | Release date: | 2021-03-17 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Self-association of MreC as a regulatory signal in bacterial cell wall elongation.
Nat Commun, 12, 2021
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6ZM0
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7B7J
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4S3L
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1AN1
 | | LEECH-DERIVED TRYPTASE INHIBITOR/TRYPSIN COMPLEX | | Descriptor: | CALCIUM ION, TRYPSIN, TRYPTASE INHIBITOR | | Authors: | Priestle, J.P, Di Marco, S. | | Deposit date: | 1997-06-26 | | Release date: | 1998-07-01 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Structure of the complex of leech-derived tryptase inhibitor (LDTI) with trypsin and modeling of the LDTI-tryptase system.
Structure, 5, 1997
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6I1Y
 | | Vibrio vulnificus EpsD | | Descriptor: | General secretion pathway protein GspD | | Authors: | Contreras-Martel, C, Farias Estrozi, L. | | Deposit date: | 2018-10-30 | | Release date: | 2019-04-10 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure and assembly of pilotin-dependent and -independent secretins of the type II secretion system.
Plos Pathog., 15, 2019
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5CPR
 | | The novel SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity | | Descriptor: | 6,7-dichloro-N-cyclopentyl-4-(pyridin-4-yl)phthalazin-1-amine, Histone-lysine N-methyltransferase SUV420H1, S-ADENOSYLMETHIONINE, ... | | Authors: | Jakob, C.G, Upadhyay, A.K, Sun, C. | | Deposit date: | 2015-07-21 | | Release date: | 2017-01-25 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.22 Å) | | Cite: | The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity.
Nat. Chem. Biol., 13, 2017
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5IKC
 | | X-RAY STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN in complex with FAB | | Descriptor: | CHLORIDE ION, Ighg protein, MAb 6H10 light chain, ... | | Authors: | Ruf, A, Stihle, M, Benz, J, Thoma, R, Rudolph, M.G. | | Deposit date: | 2016-03-03 | | Release date: | 2016-05-18 | | Last modified: | 2020-03-11 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies.
J.Biol.Chem., 291, 2016
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