6Y1Z

Mouse serotonin 5HT3 receptor in complex with palonosetron

Summary for 6Y1Z

Entry DOI	10.2210/pdb6y1z/pdb
EMDB information	10673
Descriptor	5-hydroxytryptamine receptor 3A, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywords	receptor, pentameric ligand-gated ion channel, antiemetic, transport protein
Biological source	Mus musculus (house mouse)
Total number of polymer chains	5
Total formula weight	327858.32
Authors	Zarkadas, E.,Perot, J.,Nury, H. (deposition date: 2020-02-14, release date: 2020-03-04, Last modification date: 2022-09-14)
Primary citation	Zarkadas, E.,Zhang, H.,Cai, W.,Effantin, G.,Perot, J.,Neyton, J.,Chipot, C.,Schoehn, G.,Dehez, F.,Nury, H. The Binding of Palonosetron and Other Antiemetic Drugs to the Serotonin 5-HT3 Receptor. Structure, 28:1131-1140.e4, 2020 Cited by PubMed: 32726573 DOI: 10.1016/j.str.2020.07.004 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.82 Å)

Structure validation