7OSW
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7DMO
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7DMN
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![BU of 7dmn by Molmil](/molmil-images/mine/7dmn) | Crystal structure of two pericyclases catalyzing [4+2] cycloaddition | Descriptor: | Diels-Alderase fsa2, GLYCEROL | Authors: | Chi, C.B, Wang, Z.D, Liu, T, Zhang, Z.Y, Ma, M. | Deposit date: | 2020-12-04 | Release date: | 2021-10-06 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structures of Fsa2 and Phm7 Catalyzing [4 + 2] Cycloaddition Reactions with Reverse Stereoselectivities in Equisetin and Phomasetin Biosynthesis. Acs Omega, 6, 2021
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1VBS
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![BU of 1vbs by Molmil](/molmil-images/mine/1vbs) | STRUCTURE OF CYCLOPHILIN COMPLEXED WITH (D)ALA CONTAINING TETRAPEPTIDE | Descriptor: | CYCLOPHILIN A, TETRAPEPTIDE | Authors: | Zhao, Y, Chen, Y, Schutkowski, M, Fischer, G, Ke, H. | Deposit date: | 1998-06-16 | Release date: | 1999-01-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mapping the stereospecificity of peptidyl prolyl cis/trans isomerases. FEBS Lett., 432, 1998
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6LE0
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4X9Z
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![BU of 4x9z by Molmil](/molmil-images/mine/4x9z) | Dimeric conotoxin alphaD-GeXXA | Descriptor: | alphaD-conotoxin GeXXA from the venom of Conus generalis | Authors: | Xu, S, Zhang, T, Kompella, S, Adams, D, Ding, J, Wang, C. | Deposit date: | 2014-12-12 | Release date: | 2015-12-02 | Last modified: | 2020-02-05 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Conotoxin alpha D-GeXXA utilizes a novel strategy to antagonize nicotinic acetylcholine receptors Sci Rep, 5, 2015
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8DWI
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7QCX
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![BU of 7qcx by Molmil](/molmil-images/mine/7qcx) | Two-state liquid NMR Structure of a PDZ2 Domain from hPTP1E, apo form | Descriptor: | Tyrosine-protein phosphatase non-receptor type 13 | Authors: | Ashkinadze, D, Kadavath, H, Chi, C, Friedmann, M, Strotz, D, Kumari, P, Minges, M, Cadalbert, R, Koenigl, S, Guentert, P, Voegeli, B, Riek, R. | Deposit date: | 2021-11-25 | Release date: | 2022-09-07 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Atomic resolution protein allostery from the multi-state structure of a PDZ domain. Nat Commun, 13, 2022
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7QCY
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![BU of 7qcy by Molmil](/molmil-images/mine/7qcy) | Two-state liquid NMR Structure of a PDZ2 Domain from hPTP1E, complexed with RA-GEF2 peptide | Descriptor: | Tyrosine-protein phosphatase non-receptor type 13 | Authors: | Ashkinadze, D, Kadavath, H, Chi, C, Friedmann, M, Strotz, D, Kumari, P, Minges, M, Cadalbert, R, Koenigl, S, Guentert, P, Voegeli, B, Riek, R. | Deposit date: | 2021-11-25 | Release date: | 2022-09-07 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Atomic resolution protein allostery from the multi-state structure of a PDZ domain. Nat Commun, 13, 2022
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7DXO
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7CRN
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8AW2
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![BU of 8aw2 by Molmil](/molmil-images/mine/8aw2) | Mouse serotonin 5-HT3A receptor in complex with vortioxetine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 3A, ... | Authors: | Lopez-Sanchez, U, Nury, H. | Deposit date: | 2022-08-29 | Release date: | 2024-03-06 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.01 Å) | Cite: | Structural determinants for activity of the antidepressant vortioxetine at human and rodent 5-HT 3 receptors. Nat.Struct.Mol.Biol., 2024
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8AXD
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![BU of 8axd by Molmil](/molmil-images/mine/8axd) | Human serotonin 5-HT3A receptor (apo, resting conformation) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 3A | Authors: | Lopez-Sanchez, U, Nury, H. | Deposit date: | 2022-08-31 | Release date: | 2024-03-06 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | Structural determinants for activity of the antidepressant vortioxetine at human and rodent 5-HT 3 receptors. Nat.Struct.Mol.Biol., 2024
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2LMZ
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5VL7
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![BU of 5vl7 by Molmil](/molmil-images/mine/5vl7) | PCSK9 complex with Fab33 | Descriptor: | Fab33 heavy chain, Fab33 light chain, Proprotein convertase subtilisin/kexin type 9 | Authors: | Eigenbrot, C, Shia, S. | Deposit date: | 2017-04-25 | Release date: | 2017-08-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Discovery of a cryptic peptide-binding site on PCSK9 and design of antagonists. Nat. Struct. Mol. Biol., 24, 2017
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4NWK
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![BU of 4nwk by Molmil](/molmil-images/mine/4nwk) | Crystal structure of hepatis c virus protease (ns3) complexed with bms-605339 aka n-(tert-butoxycarbonyl)-3-me thyl-l-valyl-(4r)-n-((1r,2s)-1-((cyclopropylsulfonyl)carba moyl)-2-vinylcyclopropyl)-4-((6-methoxy-1-isoquinolinyl)ox y)-l-prolinamide | Descriptor: | GLYCEROL, HCV NS3 1a Protease, N-(tert-butoxycarbonyl)-3-methyl-L-valyl-(4R)-N-{(1R,2S)-1-[(cyclopropylsulfonyl)carbamoyl]-2-ethenylcyclopropyl}-4-[(6-methoxyisoquinolin-1-yl)oxy]-L-prolinamide, ... | Authors: | Muckelbauer, J.K, Klei, H.E. | Deposit date: | 2013-12-06 | Release date: | 2014-03-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Discovery and Early Clinical Evaluation of BMS-605339, a Potent and Orally Efficacious Tripeptidic Acylsulfonamide NS3 Protease Inhibitor for the Treatment of Hepatitis C Virus Infection. J.Med.Chem., 57, 2014
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1SMF
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![BU of 1smf by Molmil](/molmil-images/mine/1smf) | Studies on an artificial trypsin inhibitor peptide derived from the mung bean inhibitor | Descriptor: | BOWMAN-BIRK TYPE TRYPSIN INHIBITOR, CALCIUM ION, TRYPSIN | Authors: | Huang, Q, Li, Y, Zhang, S, Liu, S, Tang, Y, Qi, C. | Deposit date: | 1992-10-24 | Release date: | 1994-07-31 | Last modified: | 2017-06-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Studies on an artificial trypsin inhibitor peptide derived from the mung bean trypsin inhibitor: chemical synthesis, refolding, and crystallographic analysis of its complex with trypsin. J.Biochem.(Tokyo), 116, 1994
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2JQB
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![BU of 2jqb by Molmil](/molmil-images/mine/2jqb) | Solution structure of a novel D-amiNo acid containing conopeptide, conomarphin at pH 5 | Descriptor: | Conomarphin | Authors: | Huang, F, Du, W, Han, Y, Wang, C, Chi, C. | Deposit date: | 2007-05-31 | Release date: | 2008-06-03 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Solution structure of a novel D-amiNo acid containing conopeptide, conomarphin at pH 5 To be Published
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1G11
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![BU of 1g11 by Molmil](/molmil-images/mine/1g11) | TOLUENE-4-MONOOXYGENASE CATALYTIC EFFECTOR PROTEIN NMR STRUCTURE | Descriptor: | TOLUENE-4-MONOOXYGENASE CATALYTIC EFFECTOR | Authors: | Hemmi, H, Studts, J.M, Chae, Y.K, Song, J, Markley, J.L, Fox, B.G. | Deposit date: | 2000-10-10 | Release date: | 2001-05-09 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the toluene 4-monooxygenase effector protein (T4moD). Biochemistry, 40, 2001
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2YYF
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![BU of 2yyf by Molmil](/molmil-images/mine/2yyf) | Purification and structural characterization of a D-amino acid containing conopeptide, marmophine, from Conus marmoreus | Descriptor: | M-conotoxin mr12 | Authors: | Huang, F, Du, W, Han, Y, Wang, C. | Deposit date: | 2007-04-29 | Release date: | 2008-04-08 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Purification and structural characterization of a D-amino acid-containing conopeptide, conomarphin, from Conus marmoreus. Febs J., 275, 2008
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5HZC
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![BU of 5hzc by Molmil](/molmil-images/mine/5hzc) | Crystal structure of the complex PPARgamma/AL26-29 | Descriptor: | 2-methyl-2-[4-(naphthalen-1-yl)phenoxy]propanoic acid, Peroxisome proliferator-activated receptor gamma | Authors: | Pochetti, G, Montanari, R, Capelli, D, Loiodice, F, Laghezza, A, Lavecchia, A. | Deposit date: | 2016-02-02 | Release date: | 2016-11-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for PPAR partial or full activation revealed by a novel ligand binding mode. Sci Rep, 6, 2016
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1G10
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![BU of 1g10 by Molmil](/molmil-images/mine/1g10) | TOLUENE-4-MONOOXYGENASE CATALYTIC EFFECTOR PROTEIN NMR STRUCTURE | Descriptor: | TOLUENE-4-MONOOXYGENASE CATALYTIC EFFECTOR | Authors: | Hemmi, H, Studts, J.M, Chae, Y.K, Song, J, Markley, J.L, Fox, B.G. | Deposit date: | 2000-10-10 | Release date: | 2001-05-09 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the toluene 4-monooxygenase effector protein (T4moD). Biochemistry, 40, 2001
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5HYK
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![BU of 5hyk by Molmil](/molmil-images/mine/5hyk) | Crystal structure of the complex PPARalpha/AL26-29 | Descriptor: | 2-methyl-2-[4-(naphthalen-1-yl)phenoxy]propanoic acid, Peroxisome proliferator-activated receptor alpha | Authors: | Pochetti, G, Montanari, R, Capelli, D, Loiodice, F, Laghezza, A, Lavecchia, A. | Deposit date: | 2016-02-01 | Release date: | 2016-11-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Structural basis for PPAR partial or full activation revealed by a novel ligand binding mode. Sci Rep, 6, 2016
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7E4M
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7E4O
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