5HYK
Crystal structure of the complex PPARalpha/AL26-29
Summary for 5HYK
| Entry DOI | 10.2210/pdb5hyk/pdb |
| Descriptor | Peroxisome proliferator-activated receptor alpha, 2-methyl-2-[4-(naphthalen-1-yl)phenoxy]propanoic acid (3 entities in total) |
| Functional Keywords | nuclear receptor, transcription factor, diabetes, bundle of alpha-helices, transcription |
| Biological source | Homo sapiens (Human) |
| Cellular location | Nucleus: Q07869 |
| Total number of polymer chains | 1 |
| Total formula weight | 31031.21 |
| Authors | Pochetti, G.,Montanari, R.,Capelli, D.,Loiodice, F.,Laghezza, A.,Lavecchia, A. (deposition date: 2016-02-01, release date: 2016-11-23, Last modification date: 2024-01-10) |
| Primary citation | Capelli, D.,Cerchia, C.,Montanari, R.,Loiodice, F.,Tortorella, P.,Laghezza, A.,Cervoni, L.,Pochetti, G.,Lavecchia, A. Structural basis for PPAR partial or full activation revealed by a novel ligand binding mode. Sci Rep, 6:34792-34792, 2016 Cited by PubMed: 27708429DOI: 10.1038/srep34792 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.83 Å) |
Structure validation
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