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7URJ
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BU of 7urj by Molmil
Backbone-modified variant of the B domain of Staphylococcal protein A: beta3- and ACPC-residues in helix 2
Descriptor: Staphylococcal protein A
Authors:Santhouse, J.R, Leung, J.M.G, Chong, L.T, Horne, W.S.
Deposit date:2022-04-22
Release date:2023-05-03
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Effects of altered backbone composition on the folding kinetics and mechanism of an ultrafast-folding protein.
Chem Sci, 15, 2024
7Y3F
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BU of 7y3f by Molmil
Structure of the Anabaena PSI-monomer-IsiA supercomplex
Descriptor: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ...
Authors:Nagao, R, Kato, K, Hamaguchi, T, Kawakami, K, Yonekura, K, Shen, J.R.
Deposit date:2022-06-10
Release date:2023-03-01
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2.62 Å)
Cite:Structure of a monomeric photosystem I core associated with iron-stress-induced-A proteins from Anabaena sp. PCC 7120.
Nat Commun, 14, 2023
7XQP
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BU of 7xqp by Molmil
PSI-LHCI-LHCII-Lhcb9 supercomplex of Physcomitrella patens
Descriptor: (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ...
Authors:Zhang, S, Tang, K.L, Li, X.Y, Wang, W.D, Yan, Q.J, Shen, L.L, Kuang, T.Y, Han, G.Y, Shen, J.R, Zhang, X.
Deposit date:2022-05-08
Release date:2023-04-26
Last modified:2023-06-07
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Structural insights into a unique PSI-LHCI-LHCII-Lhcb9 supercomplex from moss Physcomitrium patens.
Nat.Plants, 9, 2023
2RKM
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BU of 2rkm by Molmil
STRUCTURE OF OPPA COMPLEXED WITH LYS-LYS
Descriptor: LYSINE, OLIGO-PEPTIDE BINDING PROTEIN, URANYL (VI) ION
Authors:Sleigh, S.H, Tame, J.R.H, Wilkinson, A.J.
Deposit date:1997-03-25
Release date:1997-07-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Peptide binding in OppA, the crystal structures of the periplasmic oligopeptide binding protein in the unliganded form and in complex with lysyllysine.
Biochemistry, 36, 1997
5M4X
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BU of 5m4x by Molmil
Mutant glyceraldehyde dehydrogenase (F34M+Y399C+S405N) from Thermoplasma acidophilum
Descriptor: D-glyceraldehyde dehydrogenase (NADP(+))
Authors:Iermak, I, Mesters, J.R, Kuta Smatanova, I.
Deposit date:2016-10-19
Release date:2017-12-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.56 Å)
Cite:Mutant glyceraldehyde dehydrogenase (F34M+Y399C+S405N) from Thermoplasma acidophilum
To Be Published
5LXW
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BU of 5lxw by Molmil
Atomic resolution X-ray crystal structure of cisplatin bound to hen egg white lysozyme stored for 5 years on the shelf
Descriptor: AMMONIA, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
Authors:Helliwell, J.R.
Deposit date:2016-09-22
Release date:2016-10-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1 Å)
Cite:Atomic resolution X-ray crystal structure of cisplatin bound to hen egg white lysozyme stored for 5 years 'on the shelf'
Zenodo, 2016
8SO0
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BU of 8so0 by Molmil
Cryo-EM structure of the PP2A:B55-FAM122A complex
Descriptor: FE (III) ION, PPP2R1A-PPP2R2A-interacting phosphatase regulator 1, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform, ...
Authors:Fuller, J.R, Padi, S.K.R, Peti, W, Page, R.
Deposit date:2023-04-28
Release date:2023-10-25
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (2.79961 Å)
Cite:Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19.
Nature, 625, 2024
8SMH
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BU of 8smh by Molmil
Chimeric ETS-domain of murine PU.1 harboring the corresponding beta-strand 3 (S3) residues from murine Ets-1 in complex with d(AATAAGCGGAAGTGGG)
Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ...
Authors:Terrell, J.R, Poon, G.M.K.
Deposit date:2023-04-26
Release date:2023-11-29
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors.
Structure, 32, 2024
8SP1
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BU of 8sp1 by Molmil
Chimeric ETS-domain of murine PU.1 harboring the corresponding beta-strand 3 (S3) residues from murine Ets-1 in complex with d(AATAAGCGIAAGTGGG)
Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*IP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ...
Authors:Terrell, J.R, Poon, G.M.K.
Deposit date:2023-05-01
Release date:2023-11-29
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors.
Structure, 32, 2024
8SMJ
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BU of 8smj by Molmil
Chimeric ETS-domain of murine PU.1 harboring the corresponding beta-strand 3 (S3) residues from murine Ets-1 in complex with d(AATAAGCGGAATGGGG)
Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), Transcription factor PU.1
Authors:Terrell, J.R, Poon, G.M.K.
Deposit date:2023-04-26
Release date:2023-11-29
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors.
Structure, 32, 2024
8SVG
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BU of 8svg by Molmil
Ubiquitin variant i53 in complex with 53BP1 Tudor domain
Descriptor: Tumor protein p53 binding protein 1, Ubiquitin variant i53
Authors:Holden, J.K, Partridge, J.R, Wibowo, A.S, Mulichak, A.
Deposit date:2023-05-16
Release date:2024-03-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair.
Nat Commun, 15, 2024
8SVH
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BU of 8svh by Molmil
Ubiquitin variant i53 mutant L67R bound to 53BP1 Tudor Domain
Descriptor: Tumor protein p53 binding protein 1, Ubiquitin variant i53: mutant L67R
Authors:Holden, J.K, Partridge, J.R, Wibowo, A.S, Mulichak, A.
Deposit date:2023-05-16
Release date:2024-03-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair.
Nat Commun, 15, 2024
8SVI
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BU of 8svi by Molmil
Ubiquitin variant i53:Mutant L67H with 53BP1 Tudor domain
Descriptor: GLYCEROL, Tumor protein p53 binding protein 1, Ubiquitin Variant i53: Mutant L67H
Authors:Partridge, J.R, Holden, J.K, Wibowo, A.S, Mulichak, A.
Deposit date:2023-05-16
Release date:2024-03-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair.
Nat Commun, 15, 2024
8SVJ
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BU of 8svj by Molmil
Ubiquitin variant i53: mutant VHH with 53BP1 Tudor domain
Descriptor: GLYCEROL, Tumor protein p53 binding protein 1, Ubiquitin varient i53 mutant VHH
Authors:Holden, J, Partridge, J.R, Wibowo, A.S, Mulichak, A.
Deposit date:2023-05-16
Release date:2024-03-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair.
Nat Commun, 15, 2024
8T0O
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BU of 8t0o by Molmil
Fab from mAb RB2AT_87
Descriptor: CHLORIDE ION, RB2AT_87 Fab Heavy chain, RB2AT_87 Fab Light chain
Authors:Kreutzer, A.G, Malonis, R.J, Lai, J.R, Nowick, J.S.
Deposit date:2023-06-01
Release date:2024-03-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Generation and Study of Antibodies against Two Triangular Trimers Derived from A beta.
Pept Sci (Hoboken), 116, 2024
8SJK
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BU of 8sjk by Molmil
Pembrolizumab Caffeine crystal
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY HEAVY CHAIN, ANTIBODY LIGHT CHAIN, ...
Authors:Larpent, P, Codan, L, Bothe, J.R, Stueber, D, Reichert, P, Fischmann, T, Su, Y, Pabit, S, Gupta, S, Iuzzolino, L, Cote, A.
Deposit date:2023-04-18
Release date:2024-04-24
Last modified:2024-08-14
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Small-Angle X-ray Scattering as a Powerful Tool for Phase and Crystallinity Assessment of Monoclonal Antibody Crystallites in Support of Batch Crystallization.
Mol Pharm., 21, 2024
8SZ8
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BU of 8sz8 by Molmil
Cryo-EM of the GDP-bound human dynamin polymer assembled on the membrane in the super constricted state (full helix)
Descriptor: Dynamin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E.
Deposit date:2023-05-27
Release date:2024-05-01
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission.
Dev.Cell, 59, 2024
8SZ4
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BU of 8sz4 by Molmil
Cryo-EM of the GDP-bound human dynamin polymer assembled on the membrane in the super constricted state showing the PH domain
Descriptor: Dynamin-1
Authors:Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E.
Deposit date:2023-05-26
Release date:2024-05-01
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission.
Dev.Cell, 59, 2024
8T0K
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BU of 8t0k by Molmil
Cryo-EM of the GDP-bound human dynamin (full-length) polymer assembled on the membrane in the super constricted state
Descriptor: Dynamin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E.
Deposit date:2023-06-01
Release date:2024-05-01
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission.
Dev.Cell, 59, 2024
8SZ7
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BU of 8sz7 by Molmil
Cryo-EM of the GDP-bound human dynamin polymer assembled on the membrane in the super constricted state showing the second PH domain
Descriptor: Dynamin-1
Authors:Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E.
Deposit date:2023-05-27
Release date:2024-05-01
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission.
Dev.Cell, 59, 2024
8SXZ
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BU of 8sxz by Molmil
Cryo-EM of the GDP-bound human dynamin polymer assembled on the membrane in the super constricted state
Descriptor: Dynamin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E.
Deposit date:2023-05-24
Release date:2024-05-01
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission.
Dev.Cell, 59, 2024
8T0R
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BU of 8t0r by Molmil
Cryo-EM of the GDP-bound human dynamin (full-length) polymer assembled on the membrane in the super constricted state (full helix)
Descriptor: Dynamin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E.
Deposit date:2023-06-01
Release date:2024-05-01
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (3.97 Å)
Cite:Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission.
Dev.Cell, 59, 2024
8SH7
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BU of 8sh7 by Molmil
TUBB4B and TUBA1A Heterodimer from Human Respiratory Doublet Microtubules
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Anderson, J.R, Gui, M, Brown, A.
Deposit date:2023-04-13
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:TUBB4B variants specifically impact ciliary function, causing a ciliopathic spectrum
To Be Published
8T4N
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BU of 8t4n by Molmil
DB1976 Bound to the DNA Sequence 5'-CGCGAATTCGCG-3
Descriptor: (2M,2'M)-2,2'-(selenophene-2,5-diyl)di(1H-benzimidazole-6-carboximidamide), DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3')
Authors:Terrell, J.R, Poon, G.M.K, Wilson, W.D.
Deposit date:2023-06-09
Release date:2024-06-12
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structural studies on the PU.1 inhibitory mechanism by diamidine minor groove binders
To Be Published
8T8N
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BU of 8t8n by Molmil
Venezuelan Equine Encephalitis Virus (VEEV) Nonstructural Protein 2 (nsP2) Cysteine Protease Inhibited with CA074
Descriptor: Protease nsP2, [PROPYLAMINO-3-HYDROXY-BUTAN-1,4-DIONYL]-ISOLEUCYL-PROLINE
Authors:Compton, J.R, Legler, P.M.
Deposit date:2023-06-22
Release date:2023-08-09
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:In Silico Screening of Inhibitors of the Venezuelan Equine Encephalitis Virus Nonstructural Protein 2 Cysteine Protease.
Viruses, 15, 2023

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