6P65
 
 | | HIV Env 16055 NFL TD 2CC+ in complex with antibody 1C2 fragment antigen binding | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Ozorowski, G, Torres, J.L, Ward, A.B. | | Deposit date: | 2019-05-31 | | Release date: | 2019-11-20 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.94 Å) | | Cite: | Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability.
Immunity, 51, 2019
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6MHG
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6PW6
 | | The HIV-1 Envelope Glycoprotein Clone BG505 SOSIP.664 in Complex with Three Copies of the Bovine Broadly Neutralizing Antibody, NC-Cow1, Fragment Antigen Binding Domain | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Broadly Neutralizing Antibody NC-Cow1 Heavy Chain, ... | | Authors: | Berndsen, Z.T, Ward, A.B. | | Deposit date: | 2019-07-22 | | Release date: | 2020-06-24 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Structural basis of broad HIV neutralization by a vaccine-induced cow antibody.
Sci Adv, 6, 2020
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6MGV
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6MLM
 | | H7 HA0 in complex with Fv from H7.5 IgG | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain Fv of H7.5 Fab, Hemagglutinin HA1 chain, ... | | Authors: | Pallesen, J, Turner, H.L, Ward, A.B. | | Deposit date: | 2018-09-27 | | Release date: | 2019-02-20 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor-binding head domains.
PLoS Biol., 17, 2019
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6MGW
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6PZ8
 | | MERS S0 trimer in complex with variable domain of antibody G2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, G2 heavy chain, ... | | Authors: | Bowman, C.A, Pallesen, J, Ward, A.B. | | Deposit date: | 2019-07-31 | | Release date: | 2019-10-09 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (4.19 Å) | | Cite: | Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD.
Cell Rep, 28, 2019
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6NUR
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6NC2
 | | AMC011 v4.2 SOSIP Env trimer in complex with fusion peptide targeting antibody ACS202 fragment antigen binding | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AMC011 v4.2 SOSIP gp120, ... | | Authors: | Cottrell, C.A, Ozorowski, G, Yuan, M, Copps, J, Wilson, I.A, Ward, A.B. | | Deposit date: | 2018-12-10 | | Release date: | 2019-06-19 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (5.2 Å) | | Cite: | Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies.
Cell Host Microbe, 25, 2019
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6NF5
 | | BG505 MD64 N332-GT5 SOSIP trimer in complex with BG18-like precursor HMP1 fragmentantigen binding and base-binding RM20A3 fragment antigen binding | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG18-like precursor HMP1 fragment antigen binding heavy chain, ... | | Authors: | Ozorowski, G, Torres, J.L, Steichen, J.M, Schief, W.R, Ward, A.B. | | Deposit date: | 2018-12-18 | | Release date: | 2019-11-06 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.71 Å) | | Cite: | A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses.
Science, 366, 2019
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6OHY
 | | Chimpanzee SIV Env trimeric ectodomain. | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Pallesen, J, Andrabi, R, de Val, N, Burton, D.R, Ward, A.B. | | Deposit date: | 2019-04-08 | | Release date: | 2019-06-05 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | The Chimpanzee SIV Envelope Trimer: Structure and Deployment as an HIV Vaccine Template.
Cell Rep, 27, 2019
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6NIJ
 | | PGT145 Fab in complex with full length AMC011 HIV-1 Env | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AMC011 Glycoprotein 120, ... | | Authors: | Cottrell, C.A, Torrents de la Pena, A, Rantalainen, K, Torres, J.L, Ward, A.B. | | Deposit date: | 2018-12-29 | | Release date: | 2019-07-31 | | Last modified: | 2023-04-05 | | Method: | ELECTRON MICROSCOPY (5.7 Å) | | Cite: | Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics.
Plos Pathog., 15, 2019
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6NUS
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6NF6
 | | Structure of chicken Otop3 in nanodiscs | | Descriptor: | CHOLESTEROL HEMISUCCINATE, Otopetrin3 | | Authors: | Saotome, K, Lee, W.H, Liman, E.R, Ward, A.B. | | Deposit date: | 2018-12-18 | | Release date: | 2019-06-05 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.32 Å) | | Cite: | Structures of the otopetrin proton channels Otop1 and Otop3.
Nat.Struct.Mol.Biol., 26, 2019
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6NFC
 | | BG505 MD64 N332-GT5 SOSIP trimer in complex with BG18-like precursor HMP42 fragmentantigen binding and base-binding RM20A3 fragment antigen binding | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG18-like precursor HMP42 fragment antigen binding heavy chain, ... | | Authors: | Ozorowski, G, Torres, J.L, Ward, A.B. | | Deposit date: | 2018-12-19 | | Release date: | 2019-11-06 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.43 Å) | | Cite: | A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses.
Science, 366, 2019
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6NC3
 | | AMC011 v4.2 SOSIP Env trimer in complex with fusion peptide targeting antibody VRC34 fragment antigen binding | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Env AMC011 v4.2 SOSIP gp120, ... | | Authors: | Cottrell, C.A, Ozorowski, G, Torres, J.L, Ward, A.B. | | Deposit date: | 2018-12-10 | | Release date: | 2019-06-19 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies.
Cell Host Microbe, 25, 2019
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6NUT
 | | Ebola virus nucleoprotein - RNA complex | | Descriptor: | Nucleoprotein, RNA (5'-R(P*AP*AP*AP*AP*AP*A)-3') | | Authors: | Kirchdoerfer, R.N, Ward, A.B. | | Deposit date: | 2019-02-01 | | Release date: | 2019-05-01 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Cryo-EM structure of the Ebola virus nucleoprotein-RNA complex.
Acta Crystallogr.,Sect.F, 75, 2019
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6NF4
 | | Structure of zebrafish Otop1 in nanodiscs | | Descriptor: | CHOLESTEROL, CHOLESTEROL HEMISUCCINATE, Otopetrin1 | | Authors: | Saotome, K, Lee, W.H, Liman, E.R, Ward, A.B. | | Deposit date: | 2018-12-18 | | Release date: | 2019-06-05 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (2.98 Å) | | Cite: | Structures of the otopetrin proton channels Otop1 and Otop3.
Nat.Struct.Mol.Biol., 26, 2019
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6U59
 | | HIV-1 B41 SOSIP.664 in complex with rabbit antibody 13B | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SOSIP.664 gp120,SOSIP.664 gp120, ... | | Authors: | Yang, Y.R, Ward, A.B. | | Deposit date: | 2019-08-27 | | Release date: | 2020-01-29 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.86 Å) | | Cite: | Autologous Antibody Responses to an HIV Envelope Glycan Hole Are Not Easily Broadened in Rabbits.
J.Virol., 94, 2020
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6UYE
 | | EBOV GPdMuc Makona bound to rEBOV-548 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody rEBOV-548 Fab, ... | | Authors: | Murin, C.D, Ward, A.B. | | Deposit date: | 2019-11-13 | | Release date: | 2020-03-11 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.96 Å) | | Cite: | Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization.
Immunity, 52, 2020
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6VFJ
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6VFH
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6VFK
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6V0R
 | | BG505 SOSIP.664 Trimer | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Nogal, B, Cottrell, C.A, Ward, A.B. | | Deposit date: | 2019-11-19 | | Release date: | 2020-04-01 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.87 Å) | | Cite: | Mapping Polyclonal Antibody Responses in Non-human Primates Vaccinated with HIV Env Trimer Subunit Vaccines.
Cell Rep, 30, 2020
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6VFI
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