7KQS
 
 | | A 1.68-A resolution 3-fluoro-L-tyrosine bound crystal structure of heme-dependent tyrosine hydroxylase | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-FLUOROTYROSINE, ... | | Authors: | Wang, Y, Liu, A. | | Deposit date: | 2020-11-17 | | Release date: | 2021-03-31 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.677 Å) | | Cite: | Molecular Rationale for Partitioning between C-H and C-F Bond Activation in Heme-Dependent Tyrosine Hydroxylase.
J.Am.Chem.Soc., 143, 2021
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7KQR
 | | A 1.89-A resolution substrate-bound crystal structure of heme-dependent tyrosine hydroxylase from S. sclerotialus | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Heme-dependent L-tyrosine hydroxylase, ... | | Authors: | Wang, Y, Shin, I, Liu, A. | | Deposit date: | 2020-11-17 | | Release date: | 2021-03-31 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Molecular Rationale for Partitioning between C-H and C-F Bond Activation in Heme-Dependent Tyrosine Hydroxylase.
J.Am.Chem.Soc., 143, 2021
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7KQU
 | | A 1.58-A resolution crystal structure of ferric-hydroperoxo intermediate of L-tyrosine hydroxylase in complex with 3-fluoro-L-tyrosine | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-FLUOROTYROSINE, ... | | Authors: | Wang, Y, Davis, I, Liu, A. | | Deposit date: | 2020-11-17 | | Release date: | 2021-03-31 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.579 Å) | | Cite: | Molecular Rationale for Partitioning between C-H and C-F Bond Activation in Heme-Dependent Tyrosine Hydroxylase.
J.Am.Chem.Soc., 143, 2021
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7KQT
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8HYA
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6LK0
 | | Crystal structure of human wild type TRIP13 | | Descriptor: | Pachytene checkpoint protein 2 homolog | | Authors: | Wang, Y, Huang, J, Li, B, Xue, H, Tricot, G, Hu, L, Xu, Z, Sun, X, Chang, S, Gao, L, Tao, Y, Xu, H, Xie, Y, Xiao, W, Yu, D, Kong, Y, Chen, G, Sun, X, Lian, F, Zhang, N, Wu, X, Mao, Z, Zhan, F, Zhu, W, Shi, J. | | Deposit date: | 2019-12-17 | | Release date: | 2020-01-22 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | A Small-Molecule Inhibitor Targeting TRIP13 Suppresses Multiple Myeloma Progression.
Cancer Res., 80, 2020
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3SPK
 | | Tipranavir in Complex with a Human Immunodeficiency Virus Type 1 Protease Variant | | Descriptor: | HIV-1 protease, N-(3-{(1R)-1-[(6R)-4-HYDROXY-2-OXO-6-PHENETHYL-6-PROPYL-5,6-DIHYDRO-2H-PYRAN-3-YL]PROPYL}PHENYL)-5-(TRIFLUOROMETHYL)-2-PYRIDINESULFONAMIDE | | Authors: | Wang, Y, Liu, Z, Brunzelle, J.S, Kovari, I.A, Kovari, L.C. | | Deposit date: | 2011-07-01 | | Release date: | 2011-10-12 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.24 Å) | | Cite: | The higher barrier of darunavir and tipranavir resistance for HIV-1 protease.
Biochem.Biophys.Res.Commun., 412, 2011
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3V74
 | | crystal structure of FBF-2 in complex with gld-1 FBEa13 RNA | | Descriptor: | Fem-3 mRNA-binding factor 2, RNA (5'-R(*UP*CP*AP*UP*GP*UP*GP*CP*CP*AP*UP*AP*C)-3') | | Authors: | Wang, Y, Qiu, C, Kershner, A, Holley, C.P, Wilinski, D, Keles, S, Kimble, J, Wickens, M, Hall, T.M.T. | | Deposit date: | 2011-12-20 | | Release date: | 2012-01-04 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Divergence of PUF protein specificity through variations in an RNA-binding pocket
J.Biol.Chem., 2012
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8U2B
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8HNA
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8HN0
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2M5I
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2OCJ
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8UEJ
 | | ssRNA phage PhiCb5 virion | | Descriptor: | CALCIUM ION, Coat protein, Maturation protein | | Authors: | Wang, Y, Zhang, J. | | Deposit date: | 2023-10-01 | | Release date: | 2024-05-15 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structural mechanisms of Tad pilus assembly and its interaction with an RNA virus.
Sci Adv, 10, 2024
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8UCR
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8IUO
 | | respiratory syncytial virus nucleocapsid-like assembly | | Descriptor: | Nucleoprotein, RNA (35-MER) | | Authors: | Wang, Y, Luo, Y, Ling, X, Luo, B, Jia, G, Dong, H, Su, Z. | | Deposit date: | 2023-03-24 | | Release date: | 2023-09-06 | | Method: | ELECTRON MICROSCOPY (3.96 Å) | | Cite: | Cryo-EM structure of the nucleocapsid-like assembly of respiratory syncytial virus.
Signal Transduct Target Ther, 8, 2023
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5ZQ3
 | | PDE-Ubiquitin | | Descriptor: | SidE, Ubiquitin | | Authors: | Wang, Y, Gao, A, Gao, P. | | Deposit date: | 2018-04-17 | | Release date: | 2018-05-23 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.182 Å) | | Cite: | Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE.
Cell, 173, 2018
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5ZQ2
 | | SidE apo form | | Descriptor: | SidE | | Authors: | Wang, Y, Gao, A, Gao, P. | | Deposit date: | 2018-04-17 | | Release date: | 2018-05-23 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.704 Å) | | Cite: | Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE.
Cell, 173, 2018
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5ZRX
 | | Crystal Structure of EphA2/SHIP2 Complex | | Descriptor: | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2,Ephrin type-A receptor 2 | | Authors: | Wang, Y, Shang, Y, Li, J, Chen, W, Li, G, Wan, J, Liu, W, Zhang, M. | | Deposit date: | 2018-04-25 | | Release date: | 2018-05-30 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions.
Elife, 7, 2018
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5ZRY
 | | Crystal Structure of EphA6/Odin Complex | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Ankyrin repeat and SAM domain-containing protein 1A,Ephrin type-A receptor 6, ... | | Authors: | Wang, Y, Shang, Y, Li, J, Chen, W, Li, G, Wan, J, Liu, W, Zhang, M. | | Deposit date: | 2018-04-25 | | Release date: | 2018-05-30 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions.
Elife, 7, 2018
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8I2B
 | | Human SIRT6 in complex with inhibitor 7702 | | Descriptor: | N1-[[4-(4-aminophenyl)sulfanyl-3-(trifluoromethyl)phenyl]methoxy]benzene-1,4-dicarboxamide, NAD-dependent protein deacylase sirtuin-6, SULFATE ION, ... | | Authors: | Wang, Y. | | Deposit date: | 2023-01-14 | | Release date: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The SIRT6 in complex with inhibitor 7702
To Be Published
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5ZQ7
 | | SidE-Ubi-NAD | | Descriptor: | ADENOSINE MONOPHOSPHATE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SidE, ... | | Authors: | Wang, Y, Gao, A, Gao, P. | | Deposit date: | 2018-04-17 | | Release date: | 2018-05-23 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.847 Å) | | Cite: | Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE.
Cell, 173, 2018
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5ZQ6
 | | SidE-Ubi-ADPr | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, SidE, Ubiquitin | | Authors: | Wang, Y, Gao, A, Gao, P. | | Deposit date: | 2018-04-17 | | Release date: | 2018-05-23 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.009 Å) | | Cite: | Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE.
Cell, 173, 2018
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5ZQ5
 | | SidE-Ubi | | Descriptor: | SidE, Ubiquitin | | Authors: | Wang, Y, Gao, A, Gao, P. | | Deposit date: | 2018-04-17 | | Release date: | 2018-05-23 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.487 Å) | | Cite: | Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE.
Cell, 173, 2018
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5ZQ4
 | | PDE-Ubi-ADPr | | Descriptor: | ADENOSINE MONOPHOSPHATE, SidE, ubiquitin | | Authors: | Wang, Y, Gao, A, Gao, P. | | Deposit date: | 2018-04-17 | | Release date: | 2018-05-23 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.217 Å) | | Cite: | Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE.
Cell, 173, 2018
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