1DOZ
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![BU of 1doz by Molmil](/molmil-images/mine/1doz) | CRYSTAL STRUCTURE OF FERROCHELATASE | Descriptor: | FERROCHELATASE, MAGNESIUM ION | Authors: | Lecerof, D, Fodje, M, Hansson, A, Hansson, M, Al-Karadaghi, S. | Deposit date: | 1999-12-22 | Release date: | 2000-01-12 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and mechanistic basis of porphyrin metallation by ferrochelatase. J.Mol.Biol., 297, 2000
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3DFA
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![BU of 3dfa by Molmil](/molmil-images/mine/3dfa) | Crystal structure of kinase domain of calcium-dependent protein kinase cgd3_920 from Cryptosporidium parvum | Descriptor: | Calcium-dependent protein kinase cgd3_920 | Authors: | Wernimont, A.K, Lew, J, Lin, Y.H, Hassanali, A, Khuu, C, Alam, Z, Kozieradzki, I, Cossar, D, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Wilkstrom, M, Edwards, A.M, Hui, R, Artz, J.D, Xiao, T, Structural Genomics Consortium (SGC) | Deposit date: | 2008-06-11 | Release date: | 2008-07-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Crystal structure of kinase domain of calcium-dependent protein kinase cgd3_920 from Cryptosporidium parvum. To be Published
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2ODB
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![BU of 2odb by Molmil](/molmil-images/mine/2odb) | The crystal structure of human cdc42 in complex with the CRIB domain of human p21-activated kinase 6 (PAK6) | Descriptor: | CHLORIDE ION, Human Cell Division Cycle 42 (CDC42), MAGNESIUM ION, ... | Authors: | Ugochukwu, E, Yang, X, Elkins, J, Soundararajan, M, Pike, A.C.W, Eswaran, J, Burgess, N, Debreczeni, J.E, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, Gileadi, O, von Delft, F, Knapp, S, Doyle, D, Structural Genomics Consortium (SGC) | Deposit date: | 2006-12-22 | Release date: | 2007-01-30 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The crystal structure of human cdc42 in complex with the CRIB domain of human p21-activated kinase 6 (PAK6) To be Published
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3HHM
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![BU of 3hhm by Molmil](/molmil-images/mine/3hhm) | Crystal structure of p110alpha H1047R mutant in complex with niSH2 of p85alpha and the drug wortmannin | Descriptor: | (1S,6BR,9AS,11R,11BR)-9A,11B-DIMETHYL-1-[(METHYLOXY)METHYL]-3,6,9-TRIOXO-1,6,6B,7,8,9,9A,10,11,11B-DECAHYDRO-3H-FURO[4, 3,2-DE]INDENO[4,5-H][2]BENZOPYRAN-11-YL ACETATE, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, ... | Authors: | Amzel, L.M, Vogelstein, B, Gabelli, S.B, Mandelker, D. | Deposit date: | 2009-05-15 | Release date: | 2009-09-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A frequent kinase domain mutation that changes the interaction between PI3K{alpha} and the membrane. Proc.Natl.Acad.Sci.USA, 106, 2009
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3DME
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![BU of 3dme by Molmil](/molmil-images/mine/3dme) | Crystal structure of conserved exported protein from Bordetella pertussis. NorthEast Structural Genomics target BeR141 | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, L(+)-TARTARIC ACID, conserved exported protein | Authors: | Seetharaman, J, Abashidze, M, Wang, D, Janjua, H, Foote, E.L, Xiao, R, Liu, J, Everett, J.K, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-06-30 | Release date: | 2008-08-26 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of conserved exported protein from Bordetella pertussis. NorthEast Structural Genomics target BeR141 To be Published
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4A5V
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![BU of 4a5v by Molmil](/molmil-images/mine/4a5v) | Solution structure ensemble of the two N-terminal apple domains (residues 58-231) of Toxoplasma gondii microneme protein 4 | Descriptor: | MICRONEMAL PROTEIN 4 | Authors: | Marchant, J, Cowper, B, Liu, Y, Lai, L, Pinzan, C, Marq, J.B, Friedrich, N, Sawmynaden, K, Chai, W, Childs, R.A, Saouros, S, Simpson, P, Barreira, M.C.R, Feizi, T, Soldati-Favre, D, Matthews, S. | Deposit date: | 2011-10-28 | Release date: | 2012-04-04 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Galactose Recognition by the Apicomplexan Parasite Toxoplasma Gondii. J.Biol.Chem., 287, 2012
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4AKA
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![BU of 4aka by Molmil](/molmil-images/mine/4aka) | IPSE alpha-1, an IgE-binding crystallin | Descriptor: | IL-4-INDUCING PROTEIN | Authors: | Meyer, N.H, Mayerhofer, H, Tripsianes, K, Barths, D, Blindow, S, Bade, S, Madl, T, Frey, A, Haas, H, Mueller-Dieckmann, J, Sattler, M, Scharmm, G. | Deposit date: | 2012-02-22 | Release date: | 2013-03-13 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | A Crystallin Fold in the Interleukin-4-Inducing Principle of Schistosoma Mansoni Eggs (Ipse/Alpha-1) Mediates Ige Binding for Antigen-Independent Basophil Activation J.Biol.Chem., 290, 2015
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3DIP
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![BU of 3dip by Molmil](/molmil-images/mine/3dip) | Crystal structure of an enolase protein from the environmental genome shotgun sequencing of the Sargasso Sea | Descriptor: | SULFATE ION, enolase | Authors: | Bonanno, J.B, Freeman, J, Bain, K.T, Zhang, F, Ozyurt, S, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2008-06-20 | Release date: | 2008-07-29 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of an enolase protein from the environmental genome shotgun sequencing of the Sargasso Sea To be Published
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4A4E
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![BU of 4a4e by Molmil](/molmil-images/mine/4a4e) | Solution structure of SMN Tudor domain in complex with symmetrically dimethylated arginine | Descriptor: | N3, N4-DIMETHYLARGININE, SURVIVAL MOTOR NEURON PROTEIN | Authors: | Tripsianes, K, Madl, T, Machyna, M, Fessas, D, Englbrecht, C, Fischer, U, Neugebauer, K.M, Sattler, M. | Deposit date: | 2011-10-12 | Release date: | 2011-11-30 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Structural Basis for Dimethyl-Arginine Recognition by the Tudor Domains of Human Smn and Spf30 Proteins Nat.Struct.Mol.Biol., 18, 2011
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2PXY
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![BU of 2pxy by Molmil](/molmil-images/mine/2pxy) | Crystal structures of immune receptor complexes | Descriptor: | H-2 class II histocompatibility antigen, A-U alpha chain, A-U beta chain, ... | Authors: | Feng, D, Bond, C.J, Ely, L.K, Garcia, K.C. | Deposit date: | 2007-05-14 | Release date: | 2007-10-09 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Structural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon'. Nat.Immunol., 8, 2007
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4A4H
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![BU of 4a4h by Molmil](/molmil-images/mine/4a4h) | Solution structure of SPF30 Tudor domain in complex with asymmetrically dimethylated arginine | Descriptor: | NG,NG-DIMETHYL-L-ARGININE, SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30 | Authors: | Tripsianes, K, Madl, T, Machyna, M, Fessas, D, Englbrecht, C, Fischer, U, Neugebauer, K.M, Sattler, M. | Deposit date: | 2011-10-12 | Release date: | 2011-11-30 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | Structural Basis for Dimethyl-Arginine Recognition by the Tudor Domains of Human Smn and Spf30 Proteins Nat.Struct.Mol.Biol., 18, 2011
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3HF9
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![BU of 3hf9 by Molmil](/molmil-images/mine/3hf9) | |
2PYR
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![BU of 2pyr by Molmil](/molmil-images/mine/2pyr) | PHOTOACTIVE YELLOW PROTEIN, 1 NANOSECOND INTERMEDIATE (287K) | Descriptor: | 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN | Authors: | Perman, B, Srajer, V, Ren, Z, Teng, T.Y, Pradervand, C, Ursby, T, Bourgeois, D, Schotte, F, Wulff, M, Kort, R, Hellingwerf, K, Moffat, K. | Deposit date: | 1998-03-04 | Release date: | 1999-04-06 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Energy transduction on the nanosecond time scale: early structural events in a xanthopsin photocycle. Science, 279, 1998
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3HF3
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![BU of 3hf3 by Molmil](/molmil-images/mine/3hf3) | Old Yellow Enzyme from Thermus scotoductus SA-01 | Descriptor: | Chromate reductase, FLAVIN MONONUCLEOTIDE, SULFATE ION | Authors: | Opperman, D.J, Sewell, B.T, Litthauer, D, Isupov, M.N, Littlechild, J.A, van Heerden, E. | Deposit date: | 2009-05-11 | Release date: | 2010-02-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of a thermostable old yellow enzyme from Thermus scotoductus SA-01 Biochem.Biophys.Res.Commun., 393, 2010
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3HIZ
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![BU of 3hiz by Molmil](/molmil-images/mine/3hiz) | Crystal structure of p110alpha H1047R mutant in complex with niSH2 of p85alpha | Descriptor: | Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Authors: | Amzel, L.M, Vogelstein, B, Gabelli, S.B, Mandelker, D. | Deposit date: | 2009-05-20 | Release date: | 2009-09-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | A frequent kinase domain mutation that changes the interaction between PI3K{alpha} and the membrane. Proc.Natl.Acad.Sci.USA, 106, 2009
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3DP8
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![BU of 3dp8 by Molmil](/molmil-images/mine/3dp8) | Structural characterization of a putative endogenous metal chelator in the periplasmic nickel transporter NikA (nickel butane-1,2,4-tricarboxylate form) | Descriptor: | (2R)-butane-1,2,4-tricarboxylic acid, ACETATE ION, CHLORIDE ION, ... | Authors: | Cherrier, M.V, Cavazza, C, Bochot, C, Lemaire, D, Fontecilla-Camps, J.C. | Deposit date: | 2008-07-07 | Release date: | 2008-09-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural characterization of a putative endogenous metal chelator in the periplasmic nickel transporter NikA Biochemistry, 47, 2008
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3DB9
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![BU of 3db9 by Molmil](/molmil-images/mine/3db9) | Crystal structure of UPF0317 protein Atu3911 from Agrobacterium tumefaciens. NorthEast Strcutural Genomics target AtR186 | Descriptor: | UPF0317 protein Atu3911 | Authors: | Seetharaman, J, Abashidze, M, Wang, D, Janjua, H, Owens, L, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-05-30 | Release date: | 2008-07-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of UPF0317 protein Atu3911 from Agrobacterium tumefaciens. NorthEast Strcutural Genomics target AtR186 (CASP Target) TO BE PUBLISHED
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2PMB
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![BU of 2pmb by Molmil](/molmil-images/mine/2pmb) | Crystal structure of predicted nucleotide-binding protein from Vibrio cholerae | Descriptor: | GLYCEROL, PHOSPHATE ION, Uncharacterized protein | Authors: | Patskovsky, Y, Zhan, C, Shi, W, Toro, R, Sauder, J.M, Gilmore, J, Iizuka, M, Maletic, M, Gheyi, T, Wasserman, S.R, Smith, D, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-04-20 | Release date: | 2007-05-08 | Last modified: | 2021-02-03 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Crystal Structure of Predicted Nucleotide-Binding Protein from Vibrio Cholerae. To be Published
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1DS6
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![BU of 1ds6 by Molmil](/molmil-images/mine/1ds6) | CRYSTAL STRUCTURE OF A RAC-RHOGDI COMPLEX | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2, ... | Authors: | Scheffzek, K, Stephan, I, Jensen, O.N, Illenberger, D, Gierschik, P. | Deposit date: | 2000-01-07 | Release date: | 2000-07-12 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | The Rac-RhoGDI complex and the structural basis for the regulation of Rho proteins by RhoGDI. Nat.Struct.Biol., 7, 2000
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1DY2
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![BU of 1dy2 by Molmil](/molmil-images/mine/1dy2) | Murine collagen alpha1(XV), endostatin domain | Descriptor: | COLLAGEN ALPHA1(XV) CHAIN, SULFATE ION | Authors: | Tisi, D, Hohenester, E, Sasaki, T, Timpl, R. | Deposit date: | 2000-01-21 | Release date: | 2001-01-21 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Endostatin Derived from Collagens Xv and Xviii Differ in Structural and Binding Properties, Tissue Distribution and Anti-Angiogenic Activity J.Mol.Biol., 301, 2000
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3DDG
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![BU of 3ddg by Molmil](/molmil-images/mine/3ddg) | GOLGI MANNOSIDASE II complex with (3R,4R,5R)-3,4-Dihydroxy-5-({[(1R)-2-hydroxy-1 phenylethyl]amino}methyl) methylpyrrolidin-2-one | Descriptor: | (3R,4R,5R)-3,4-dihydroxy-5-({[(1R)-2-hydroxy-1-phenylethyl]amino}methyl)-1-methylpyrrolidin-2-one, (4R)-2-METHYLPENTANE-2,4-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Kuntz, D.A, Rose, D.R, Hoffman, D. | Deposit date: | 2008-06-05 | Release date: | 2008-07-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Functionalized pyrrolidine inhibitors of human type II alpha-mannosidases as anti-cancer agents: optimizing the fit to the active site Bioorg.Med.Chem., 16, 2008
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4A33
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![BU of 4a33 by Molmil](/molmil-images/mine/4a33) | CRYSTAL STRUCTURE OF LEISHMANIA MAJOR N-MYRISTOYLTRANSFERASE (NMT) WITH BOUND MYRISTOYL-COA AND A PYRAZOLE SULPHONAMIDE LIGAND | Descriptor: | 2,6-DICHLORO-4-(6-PIPERAZIN-1-YLPYRIDIN-3-YL)-N-(1,3,5-TRIMETHYL-1H-PYRAZOL-4-YL)BENZENESULFONAMIDE, GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, TETRADECANOYL-COA | Authors: | Robinson, D.A, Brand, S, Cleghorn, L.A.T, McElroy, S.P, Smith, V.C, Hallyburton, I, Harrison, J.R, Norcross, N.R, Norval, S, Spinks, D, Stojanovski, L, Torrie, L.S, Frearson, J.A, Brenk, R, Fairlamb, A.H, Ferguson, M.A.J, Read, K.D, Wyatt, P.G, Gilbert, I.H. | Deposit date: | 2011-09-29 | Release date: | 2011-12-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Discovery of a novel class of orally active trypanocidal N-myristoyltransferase inhibitors. J. Med. Chem., 55, 2012
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3DH4
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![BU of 3dh4 by Molmil](/molmil-images/mine/3dh4) | Crystal Structure of Sodium/Sugar symporter with bound Galactose from vibrio parahaemolyticus | Descriptor: | ERBIUM (III) ION, SODIUM ION, Sodium/glucose cotransporter, ... | Authors: | Abramson, J, Faham, S, Cascio, D. | Deposit date: | 2008-06-16 | Release date: | 2008-08-05 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The crystal structure of a sodium galactose transporter reveals mechanistic insights into Na+/sugar symport. Science, 321, 2008
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1DTV
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![BU of 1dtv by Molmil](/molmil-images/mine/1dtv) | NMR STRUCTURE OF THE LEECH CARBOXYPEPTIDASE INHIBITOR (LCI) | Descriptor: | CARBOXYPEPTIDASE INHIBITOR | Authors: | Reverter, D, Fernandez-Catalan, C, Bode, W, Holak, T.A, Aviles, F.X. | Deposit date: | 2000-01-13 | Release date: | 2000-07-19 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | Structure of a novel leech carboxypeptidase inhibitor determined free in solution and in complex with human carboxypeptidase A2. Nat.Struct.Biol., 7, 2000
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2Q2R
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![BU of 2q2r by Molmil](/molmil-images/mine/2q2r) | Trypanosoma cruzi glucokinase in complex with beta-D-glucose and ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Glucokinase 1, putative, ... | Authors: | Cordeiro, A.T, Caceres, A.J, Vertommen, D, Concepcion, J.L, Michels, P.A, Versees, W. | Deposit date: | 2007-05-29 | Release date: | 2007-10-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Crystal Structure of Trypanosoma cruzi Glucokinase Reveals Features Determining Oligomerization and Anomer Specificity of Hexose-phosphorylating Enzymes. J.Mol.Biol., 372, 2007
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