2B9D
| Crystal Structure of HPV E7 CR3 domain | Descriptor: | E7 protein, ZINC ION | Authors: | Liu, X, Clements, A, Zhao, K, Marmorstein, R. | Deposit date: | 2005-10-11 | Release date: | 2005-10-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of the human Papillomavirus E7 oncoprotein and its mechanism for inactivation of the retinoblastoma tumor suppressor. J.Biol.Chem., 281, 2006
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2ERE
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2ERG
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2ER8
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1K6O
| Crystal Structure of a Ternary SAP-1/SRF/c-fos SRE DNA Complex | Descriptor: | 5'-D(*CP*AP*CP*AP*GP*GP*AP*TP*GP*TP*CP*CP*AP*TP*AP*TP*TP*AP*GP*GP*AP*CP*A)-3', 5'-D(*TP*GP*TP*CP*CP*TP*AP*AP*TP*AP*TP*GP*GP*AP*CP*AP*TP*CP*CP*TP*GP*TP*G)-3', ETS-domain protein ELK-4, ... | Authors: | Mo, Y, Ho, W, Johnston, K, Marmorstein, R. | Deposit date: | 2001-10-16 | Release date: | 2002-01-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.19 Å) | Cite: | Crystal structure of a ternary SAP-1/SRF/c-fos SRE DNA complex. J.Mol.Biol., 314, 2001
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1M1D
| TETRAHYMENA GCN5 WITH BOUND BISUBSTRATE ANALOG INHIBITOR | Descriptor: | HISTONE H3, TGCN5 HISTONE ACETYL TRANSFERASE | Authors: | Poux, A.N, Cebrat, M, Kim, C.M, Cole, P.A, Marmorstein, R. | Deposit date: | 2002-06-18 | Release date: | 2002-10-30 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor. Proc.Natl.Acad.Sci.USA, 99, 2002
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1MJ9
| Crystal structure of yeast Esa1(C304S) mutant complexed with Coenzyme A | Descriptor: | COENZYME A, ESA1 PROTEIN, SODIUM ION | Authors: | Yan, Y, Harper, S, Speicher, D, Marmorstein, R. | Deposit date: | 2002-08-27 | Release date: | 2002-10-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The catalytic mechanism of the ESA1 histone acetyltransferase involves a self-acetylated intermediate. Nat.Struct.Biol., 9, 2002
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1MJA
| Crystal structure of yeast Esa1 histone acetyltransferase domain complexed with acetyl coenzyme A | Descriptor: | COENZYME A, Esa1 protein | Authors: | Yan, Y, Harper, S, Speicher, D, Marmorstein, R. | Deposit date: | 2002-08-27 | Release date: | 2002-10-30 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | The catalytic mechanism of the ESA1 histone acetyltransferase involves a self-acetylated intermediate. Nat.Struct.Biol., 9, 2002
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1MJB
| Crystal structure of yeast Esa1 histone acetyltransferase E338Q mutant complexed with acetyl coenzyme A | Descriptor: | ACETYL COENZYME *A, Esa1 protein | Authors: | Yan, Y, Harper, S, Speicher, D, Marmorstein, R. | Deposit date: | 2002-08-27 | Release date: | 2002-10-30 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The catalytic mechanism of the ESA1 histone acetyltransferase involves a self-acetylated intermediate. Nat.Struct.Biol., 9, 2002
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2IOI
| Crystal structure of the mouse p53 core domain at 1.55 A | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cellular tumor antigen p53, ZINC ION | Authors: | Ho, W.C, Luo, C, Zhao, K, Chai, X, Fitzgerald, M.X, Marmorstein, R. | Deposit date: | 2006-10-10 | Release date: | 2006-12-05 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | High-resolution structure of the p53 core domain: implications for binding small-molecule stabilizing compounds. Acta Crystallogr.,Sect.D, 62, 2006
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2IOM
| Mouse p53 core domain soaked with 2-propanol | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cellular tumor antigen p53, ISOPROPYL ALCOHOL, ... | Authors: | Ho, W.C, Luo, C, Zhao, K, Chai, X, Fitzgerald, M.X, Marmorstein, R. | Deposit date: | 2006-10-10 | Release date: | 2006-12-05 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | High-resolution structure of the p53 core domain: implications for binding small-molecule stabilizing compounds. ACTA CRYSTALLOGR.,SECT.D, 62, 2006
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4K2J
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2IOO
| Crystal structure of the mouse p53 core domain | Descriptor: | Cellular tumor antigen p53, ZINC ION | Authors: | Ho, W.C, Luo, C, Zhao, K, Chai, X, Fitzgerald, M.X, Marmorstein, R. | Deposit date: | 2006-10-10 | Release date: | 2006-12-05 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | High-resolution structure of the p53 core domain: implications for binding small-molecule stabilizing compounds. Acta Crystallogr.,Sect.D, 62, 2006
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2HAP
| STRUCTURE OF A HAP1-18/DNA COMPLEX REVEALS THAT PROTEIN/DNA INTERACTIONS CAN HAVE DIRECT ALLOSTERIC EFFECTS ON TRANSCRIPTIONAL ACTIVATION | Descriptor: | DNA (5'-D(*AP*CP*GP*CP*TP*AP*TP*TP*AP*TP*CP*GP*CP*TP*AP*TP*TP*AP*GP*T)-3'), DNA (5'-D(*AP*CP*TP*AP*AP*TP*AP*GP*CP*GP*AP*TP*AP*AP*TP*AP*GP*CP*GP*T)-3'), PROTEIN (HEME ACTIVATOR PROTEIN), ... | Authors: | King, D.A, Zhang, L, Guarente, L, Marmorstein, R. | Deposit date: | 1998-09-17 | Release date: | 1999-11-10 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of HAP1-18-DNA implicates direct allosteric effect of protein-DNA interactions on transcriptional activation. Nat.Struct.Biol., 6, 1999
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4LX9
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1Q1A
| Structure of the yeast Hst2 protein deacetylase in ternary complex with 2'-O-acetyl ADP ribose and histone peptide | Descriptor: | 2'-O-ACETYL ADENOSINE-5-DIPHOSPHORIBOSE, HST2 protein, Histone H4, ... | Authors: | Zhao, K, Chai, X, Marmorstein, R. | Deposit date: | 2003-07-18 | Release date: | 2003-11-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of the yeast Hst2 protein deacetylase in ternary complex with 2'-O-Acetyl ADP ribose and histone peptide. Structure, 11, 2003
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1Q17
| Structure of the yeast Hst2 protein deacetylase in ternary complex with 2'-O-acetyl ADP ribose and histone peptide | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, CHLORIDE ION, HST2 protein, ... | Authors: | Zhao, K, Chai, X, Marmorstein, R. | Deposit date: | 2003-07-18 | Release date: | 2003-11-18 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of the Yeast Hst2 Protein Deacetylase in Ternary Complex with 2'-O-Acetyl
ADP Ribose and Histone Peptide. Structure, 11, 2003
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3CO6
| Crystal Structure of FoxO1 DBD Bound to DBE1 DNA | Descriptor: | CALCIUM ION, CHLORIDE ION, DNA (5'-D(*DCP*DAP*DAP*DGP*DGP*DTP*DAP*DAP*DAP*DCP*DAP*DAP*DAP*DCP*DCP*DA)-3'), ... | Authors: | Brent, M.M, Anand, R, Marmorstein, R. | Deposit date: | 2008-03-27 | Release date: | 2008-09-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification. Structure, 16, 2008
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3COA
| Crystal Structure of FoxO1 DBD Bound to IRE DNA | Descriptor: | CALCIUM ION, DNA (5'-D(*DCP*DAP*DAP*DGP*DCP*DAP*DAP*DAP*DAP*DCP*DAP*DAP*DAP*DCP*DCP*DA)-3'), DNA (5'-D(*DTP*DGP*DGP*DTP*DTP*DTP*DGP*DTP*DTP*DTP*DTP*DGP*DCP*DTP*DTP*DG)-3'), ... | Authors: | Brent, M.M, Anand, R, Marmorstein, R. | Deposit date: | 2008-03-27 | Release date: | 2008-09-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification. Structure, 16, 2008
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3CO7
| Crystal Structure of FoxO1 DBD Bound to DBE2 DNA | Descriptor: | DNA (5'-D(*DCP*DAP*DAP*DAP*DAP*DTP*DGP*DTP*DAP*DAP*DAP*DCP*DAP*DAP*DGP*DA)-3'), DNA (5'-D(*DTP*DCP*DTP*DTP*DGP*DTP*DTP*DTP*DAP*DCP*DAP*DTP*DTP*DTP*DTP*DG)-3'), Forkhead box protein O1 | Authors: | Brent, M.M, Anand, R, Marmorstein, R. | Deposit date: | 2008-03-27 | Release date: | 2008-09-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification. Structure, 16, 2008
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1CM0
| CRYSTAL STRUCTURE OF THE PCAF/COENZYME-A COMPLEX | Descriptor: | COENZYME A, P300/CBP ASSOCIATING FACTOR | Authors: | Clements, A, Rojas, J.R, Trievel, R.C, Wang, L, Berger, S.L, Marmorstein, R. | Deposit date: | 1999-05-12 | Release date: | 1999-07-06 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the histone acetyltransferase domain of the human PCAF transcriptional regulator bound to coenzyme A. EMBO J., 18, 1999
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1CS3
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1DUX
| ELK-1/DNA STRUCTURE REVEALS HOW RESIDUES DISTAL FROM DNA-BINDING SURFACE AFFECT DNA-RECOGNITION | Descriptor: | DNA (5'-D(*AP*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP*CP*A)-3'), DNA (5'-D(*TP*GP*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP*T)-3'), ETS-DOMAIN PROTEIN ELK-1 | Authors: | Mo, Y, Vaessen, B, Johnston, K, Marmorstein, R. | Deposit date: | 2000-01-19 | Release date: | 2000-04-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of the elk-1-DNA complex reveals how DNA-distal residues affect ETS domain recognition of DNA. Nat.Struct.Biol., 7, 2000
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1BC7
| SERUM RESPONSE FACTOR ACCESSORY PROTEIN 1A (SAP-1)/DNA COMPLEX | Descriptor: | DNA (5'-D(*CP*AP*CP*AP*TP*CP*CP*TP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*AP*GP*GP*AP*TP*GP*TP*G)-3'), PROTEIN (ETS-DOMAIN PROTEIN) | Authors: | Mo, Y, Vaessen, B, Johnston, K, Marmorstein, R. | Deposit date: | 1998-05-05 | Release date: | 1999-01-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Structures of SAP-1 bound to DNA targets from the E74 and c-fos promoters: insights into DNA sequence discrimination by Ets proteins. Mol.Cell, 2, 1998
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1BC8
| STRUCTURES OF SAP-1 BOUND TO DNA SEQUENCES FROM THE E74 AND C-FOS PROMOTERS PROVIDE INSIGHTS INTO HOW ETS PROTEINS DISCRIMINATE BETWEEN RELATED DNA TARGETS | Descriptor: | DNA (5'-D(*AP*AP*CP*TP*TP*CP*CP*GP*GP*T)-3'), DNA (5'-D(*TP*AP*CP*CP*GP*GP*AP*AP*GP*T)-3'), PROTEIN (SAP-1 ETS DOMAIN), ... | Authors: | Mo, Y, Vaessen, B, Johnston, K, Marmorstein, R. | Deposit date: | 1998-05-05 | Release date: | 1998-12-01 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Structures of SAP-1 bound to DNA targets from the E74 and c-fos promoters: insights into DNA sequence discrimination by Ets proteins. Mol.Cell, 2, 1998
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