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1OZB
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BU of 1ozb by Molmil
Crystal Structure of SecB complexed with SecA C-terminus
Descriptor: Preprotein translocase secA subunit, Protein-export protein secB, ZINC ION
Authors:Zhou, J, Xu, Z.
Deposit date:2003-04-08
Release date:2003-10-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural determinants of SecB recognition by SecA in bacterial protein translocation
NAT.STRUCT.BIOL., 10, 2003
1NW1
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BU of 1nw1 by Molmil
Crystal Structure of Choline Kinase
Descriptor: CALCIUM ION, Choline kinase (49.2 kD)
Authors:Peisach, D, Gee, P, Kent, C, Xu, Z.
Deposit date:2003-02-05
Release date:2003-06-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:The Crystal Structure of Choline Kinase Reveals a Eukaryotic Protein Kinase Fold
Structure, 11, 2003
1YTV
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BU of 1ytv by Molmil
Maltose-binding protein fusion to a C-terminal fragment of the V1a vasopressin receptor
Descriptor: Maltose-binding periplasmic protein, Vasopressin V1a receptor, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Adikesavan, N.V, Mahmood, S.S, Stanley, S, Xu, Z, Wu, N, Thibonnier, M, Shoham, M.
Deposit date:2005-02-11
Release date:2005-04-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A C-terminal segment of the V1R vasopressin receptor is unstructured in the crystal structure of its chimera with the maltose-binding protein.
Acta Crystallogr.,Sect.F, 61, 2005
1ZCP
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BU of 1zcp by Molmil
Crystal Structure of a catalytic site mutant E. coli TrxA (CACA)
Descriptor: Thioredoxin 1
Authors:Collet, J.-F, Peisach, D, Bardwell, J.C, Xu, Z.
Deposit date:2005-04-12
Release date:2005-08-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of TrxA(CACA): Insights into the formation of a [2Fe-2S] iron-sulfur cluster in an Escherichia coli thioredoxin mutant
Protein Sci., 14, 2005
1UKF
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BU of 1ukf by Molmil
Crystal Structure of Pseudomonas Avirulence Protein AvrPphB
Descriptor: Avirulence protein AVRPPH3
Authors:Zhu, M, Shao, F, Innes, R.W, Dixon, J.E, Xu, Z.
Deposit date:2003-08-21
Release date:2003-12-09
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:The crystal structure of Pseudomonas avirulence protein AvrPphB: a papain-like fold with a distinct substrate-binding site.
Proc.Natl.Acad.Sci.Usa, 101, 2004
1R62
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BU of 1r62 by Molmil
Crystal structure of the C-terminal Domain of the Two-Component System Transmitter Protein NRII (NtrB)
Descriptor: Nitrogen regulation protein NR(II)
Authors:Song, Y, Peisach, D, Pioszak, A.A, Xu, Z, Ninfa, A.J.
Deposit date:2003-10-14
Release date:2004-06-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structure of the C-terminal Domain of the Two-Component System Transmitter Protein Nitrogen Regulator II (NRII; NtrB), Regulator of Nitrogen Assimilation in Escherichia coli.
Biochemistry, 43, 2004
1T11
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BU of 1t11 by Molmil
Trigger Factor
Descriptor: Trigger factor
Authors:Ludlam, A.V, Moore, B.A, Xu, Z.
Deposit date:2004-04-14
Release date:2004-09-21
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of ribosomal chaperone trigger factor from Vibrio cholerae.
Proc.Natl.Acad.Sci.USA, 101, 2004
2HZ6
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BU of 2hz6 by Molmil
The crystal structure of human IRE1-alpha luminal domain
Descriptor: Endoplasmic reticulum to nucleus signalling 1 isoform 1 variant
Authors:Kaufman, R.J, Xu, Z, Zhou, J.
Deposit date:2006-08-08
Release date:2006-08-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2LP0
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BU of 2lp0 by Molmil
The solution structure of homeodomain-protein complex
Descriptor: Geminin, Homeobox protein Hox-C9
Authors:Liu, C, Zhou, B, Xu, Z, Zhu, G.
Deposit date:2012-01-29
Release date:2012-06-06
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural basis for homeodomain recognition by the cell-cycle regulator Geminin
Proc.Natl.Acad.Sci.USA, 2012
3DYR
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BU of 3dyr by Molmil
Crystal structure of E. coli thioredoxin mutant I76T in its oxidized form
Descriptor: Thioredoxin-1
Authors:Ren, G, Bardwell, J.C.A, Xu, Z.
Deposit date:2008-07-28
Release date:2009-01-27
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Properties of the thioredoxin fold superfamily are modulated by a single amino acid residue.
J.Biol.Chem., 284, 2009
3GGZ
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BU of 3ggz by Molmil
Crystal Structure of S.cerevisiae Ist1 N-terminal domain in complex with Did2 MIM motif
Descriptor: Increased sodium tolerance protein 1, Vacuolar protein-sorting-associated protein 46
Authors:Xiao, J, Xu, Z.
Deposit date:2009-03-02
Release date:2009-09-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural basis of Ist1 function and Ist1-Did2 interaction in the multivesicular body pathway and cytokinesis.
MOLECULAR BIOLOGY OF THE CELL, 20, 2009
3GGY
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BU of 3ggy by Molmil
Crystal Structure of S.cerevisiae Ist1 N-terminal domain
Descriptor: Increased sodium tolerance protein 1
Authors:Xiao, J, Xu, Z.
Deposit date:2009-03-02
Release date:2009-09-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis of Ist1 function and Ist1-Did2 interaction in the multivesicular body pathway and cytokinesis.
MOLECULAR BIOLOGY OF THE CELL, 20, 2009
6MMZ
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BU of 6mmz by Molmil
Crystal structure of meta-AAC0038, an environmental aminoglycoside resistance enzyme, H29A mutant apoenzyme
Descriptor: Aminoglycoside N(3)-acetyltransferase, CHLORIDE ION, SULFATE ION
Authors:Stogios, P.J, Skarina, T, Xu, Z, Yim, V, Savchenko, A, Joachimiak, A, Satchell, K.J, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2018-10-01
Release date:2018-10-24
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family.
Commun Biol, 5, 2022
2LKO
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BU of 2lko by Molmil
Structural Basis of Phosphoinositide Binding to Kindlin-2 Pleckstrin Homology Domain in Regulating Integrin Activation
Descriptor: Fermitin family homolog 2, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE
Authors:Liu, J, Fukuda, K, Xu, Z.
Deposit date:2011-10-17
Release date:2011-10-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural basis of phosphoinositide binding to kindlin-2 protein pleckstrin homology domain in regulating integrin activation.
J.Biol.Chem., 286, 2011
4GVD
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BU of 4gvd by Molmil
Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ in complex with Syndecan1 Peptide
Descriptor: 5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONIC ACID(DANSYL ACID), CHLORIDE ION, SODIUM ION, ...
Authors:Liu, X, Shepherd, T.R, Murray, A.M, Xu, Z, Fuentes, E.J.
Deposit date:2012-08-30
Release date:2013-03-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The structure of the Tiam1 PDZ domain/ phospho-syndecan1 complex reveals a ligand conformation that modulates protein dynamics.
Structure, 21, 2013
4GVC
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BU of 4gvc by Molmil
Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ in complex with phosphorylated Syndecan1 Peptide
Descriptor: 5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONIC ACID(DANSYL ACID), CHLORIDE ION, SODIUM ION, ...
Authors:Liu, X, Shepherd, T.R, Murray, A.M, Xu, Z, Fuentes, E.J.
Deposit date:2012-08-30
Release date:2013-03-13
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:The structure of the Tiam1 PDZ domain/ phospho-syndecan1 complex reveals a ligand conformation that modulates protein dynamics.
Structure, 21, 2013
2OCG
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BU of 2ocg by Molmil
Crystal structure of human valacyclovir hydrolase
Descriptor: GLYCEROL, MAGNESIUM ION, MANGANESE (II) ION, ...
Authors:Lai, L, Xu, Z, Amidon, G.L.
Deposit date:2006-12-20
Release date:2008-02-05
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Molecular basis of prodrug activation by human valacyclovirase, an alpha-amino acid ester hydrolase.
J.Biol.Chem., 283, 2008
2OCI
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BU of 2oci by Molmil
Crystal structure of valacyclovir hydrolase complexed with a product analogue
Descriptor: L-TYROSINAMIDE, MAGNESIUM ION, MANGANESE (II) ION, ...
Authors:Lai, L, Xu, Z, Amidon, G.L.
Deposit date:2006-12-20
Release date:2008-02-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular basis of prodrug activation by human valacyclovirase, an alpha-amino acid ester hydrolase.
J.Biol.Chem., 283, 2008
2OCK
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BU of 2ock by Molmil
Crystal structure of valacyclovir hydrolase D123N mutant
Descriptor: MAGNESIUM ION, MANGANESE (II) ION, Valacyclovir hydrolase
Authors:Lai, L, Xu, Z, Amidon, G.L.
Deposit date:2006-12-20
Release date:2008-02-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Molecular basis of prodrug activation by human valacyclovirase, an alpha-amino acid ester hydrolase.
J.Biol.Chem., 283, 2008
2OCL
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BU of 2ocl by Molmil
Crystal structure of valacyclovir hydrolase S122A mutant
Descriptor: MAGNESIUM ION, MANGANESE (II) ION, Valacyclovir hydrolase
Authors:Lai, L, Xu, Z, Amidon, G.L.
Deposit date:2006-12-20
Release date:2008-02-05
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular basis of prodrug activation by human valacyclovirase, an alpha-amino acid ester hydrolase.
J.Biol.Chem., 283, 2008
2PFV
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BU of 2pfv by Molmil
S. cerevisiae Exo70 with additional residues to 2.1 Angrstrom resolution
Descriptor: Exocyst complex component EXO70
Authors:Moore, B.A, Robinson, H.H, Xu, Z.
Deposit date:2007-04-05
Release date:2007-05-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The crystal structure of mouse Exo70 reveals unique features of the mammalian exocyst.
J.Mol.Biol., 371, 2007
2PFT
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BU of 2pft by Molmil
The Crystal Structure of Mouse Exo70 Reveals Unique Features of the Mammalian Exocyst
Descriptor: Exocytosis Protein
Authors:Moore, B.A, Xu, Z.
Deposit date:2007-04-05
Release date:2007-05-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The crystal structure of mouse Exo70 reveals unique features of the mammalian exocyst.
J.Mol.Biol., 371, 2007
2QP9
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BU of 2qp9 by Molmil
Crystal Structure of S.cerevisiae Vps4
Descriptor: CADMIUM ION, SULFATE ION, Vacuolar protein sorting-associated protein 4
Authors:Xiao, J, Xu, Z.
Deposit date:2007-07-23
Release date:2007-10-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural characterization of the ATPase reaction cycle of endosomal AAA protein Vps4.
J.Mol.Biol., 374, 2007
3LM1
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BU of 3lm1 by Molmil
Crystal Structure Analysis of Maclura pomifera agglutinin complex with p-nitrophenyl-GalNAc
Descriptor: 4-nitrophenyl 2-acetamido-2-deoxy-beta-D-glucopyranoside, Agglutinin alpha chain, Agglutinin beta-2 chain
Authors:Huang, J, Xu, Z, Wang, D, Ogato, C, Hirama, T, Palczewski, K, Hazen, S.L, Lee, X, Young, N.M.
Deposit date:2010-01-29
Release date:2010-09-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Characterization of the secondary binding sites of Maclura pomifera agglutinin by glycan array and crystallographic analyses.
Glycobiology, 20, 2010
5XS2
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BU of 5xs2 by Molmil
CDK8-CYCC IN COMPLEX WITH COMPOUND 17:3-chloro-4-(4-pyridyl)-1H-pyrrole-2-carboxamide
Descriptor: 3-chloranyl-4-pyridin-4-yl-1H-pyrrole-2-carboxamide, Cyclin-C, Cyclin-dependent kinase 8, ...
Authors:Zhou, Z, Xu, Z.
Deposit date:2017-06-12
Release date:2017-08-09
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Discovery of potent and selective CDK8 inhibitors through FBDD approach
Bioorg. Med. Chem. Lett., 27, 2017

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