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4O59
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BU of 4o59 by Molmil
Co-enzyme Induced Conformational Changes in Bovine Eye Glyceraldehyde 3-Phosphate Dehydrogenase
Descriptor: Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Baker, B.Y, Shi, W, Wang, B, Palczewski, K.
Deposit date:2013-12-19
Release date:2014-09-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:High-resolution crystal structures of the photoreceptor glyceraldehyde 3-phosphate dehydrogenase (GAPDH) with three and four-bound NAD molecules.
Protein Sci., 23, 2014
4O63
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BU of 4o63 by Molmil
Co-enzyme Induced Conformational Changes in Bovine Eye Glyceraldehyde 3-Phosphate Dehydrogenase
Descriptor: Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Baker, B.Y, Shi, W, Wang, B, Palczewski, K.
Deposit date:2013-12-20
Release date:2014-09-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:High-resolution crystal structures of the photoreceptor glyceraldehyde 3-phosphate dehydrogenase (GAPDH) with three and four-bound NAD molecules.
Protein Sci., 23, 2014
4OU9
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BU of 4ou9 by Molmil
Crystal structure of apocarotenoid oxygenase in the presence of Triton X-100
Descriptor: Apocarotenoid-15,15'-oxygenase, CHLORIDE ION, FE (II) ION
Authors:Sui, X, Palczewski, K, Kiser, P.D.
Deposit date:2014-02-15
Release date:2014-03-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Analysis of Carotenoid Isomerase Activity in a Prototypical Carotenoid Cleavage Enzyme, Apocarotenoid Oxygenase (ACO).
J.Biol.Chem., 289, 2014
4Q95
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BU of 4q95 by Molmil
Crystal structure of HRASLS3/LRAT chimeric protein
Descriptor: HEPTANOIC ACID, HRAS-like suppressor 3, Lecithin retinol acyltransferase
Authors:Golczak, M, Kiser, P.D, Sears, A.E, Palczewski, K.
Deposit date:2014-04-29
Release date:2014-10-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:LRAT-specific domain facilitates vitamin A metabolism by domain swapping in HRASLS3.
Nat.Chem.Biol., 11, 2015
4OU8
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BU of 4ou8 by Molmil
Crystal structure of apocarotenoid oxygenase in the presence of C8E6
Descriptor: Apocarotenoid-15,15'-oxygenase, CHLORIDE ION, FE (II) ION
Authors:Sui, X, Shi, W, Palczewski, K, Kiser, P.D.
Deposit date:2014-02-15
Release date:2014-03-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Analysis of Carotenoid Isomerase Activity in a Prototypical Carotenoid Cleavage Enzyme, Apocarotenoid Oxygenase (ACO).
J.Biol.Chem., 289, 2014
4Q2R
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BU of 4q2r by Molmil
Structural Proteomics From Crude Native Rod Outer Segments
Descriptor: Creatine kinase B-type, SULFATE ION
Authors:Baker, B.Y, Shi, W, Palczewski, K.
Deposit date:2014-04-09
Release date:2014-09-03
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural Proteomics From Crude Native Rod Outer Segments
To be Published
4DOT
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BU of 4dot by Molmil
Crystal structure of human HRASLS3.
Descriptor: Group XVI phospholipase A2
Authors:Kiser, P.D, Golczak, M, Sears, A.E, Lodowski, D.T, Palczewski, K.
Deposit date:2012-02-10
Release date:2012-05-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Structural Basis for the Acyltransferase Activity of Lecithin:Retinol Acyltransferase-like Proteins.
J.Biol.Chem., 287, 2012
4DPZ
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BU of 4dpz by Molmil
Crystal structure of human HRASLS2
Descriptor: HRAS-like suppressor 2
Authors:Kiser, P.D, Golczak, M, Sears, A.E, Lodowski, D.T, Palczewski, K.
Deposit date:2012-02-14
Release date:2012-05-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structural Basis for the Acyltransferase Activity of Lecithin:Retinol Acyltransferase-like Proteins.
J.Biol.Chem., 287, 2012
4F3D
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BU of 4f3d by Molmil
Structure of RPE65: P65 crystal form grown in Fos-Choline-10
Descriptor: 2-ETHOXYETHANOL, FE (II) ION, Retinoid isomerohydrolase
Authors:Kiser, P.D, Palczewski, K.
Deposit date:2012-05-09
Release date:2012-10-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of RPE65 isomerase in a lipidic matrix reveals roles for phospholipids and iron in catalysis.
Proc.Natl.Acad.Sci.USA, 109, 2012
4F2Z
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BU of 4f2z by Molmil
Crystal structure of RPE65 in a lipid environment
Descriptor: FE (II) ION, Retinoid isomerohydrolase
Authors:Kiser, P.D, Shi, W, Palczewski, K.
Deposit date:2012-05-08
Release date:2012-10-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of RPE65 isomerase in a lipidic matrix reveals roles for phospholipids and iron in catalysis.
Proc.Natl.Acad.Sci.USA, 109, 2012
4F3A
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BU of 4f3a by Molmil
Structure of RPE65: P6522 crystal form, iridium derivative
Descriptor: FE (II) ION, IRIDIUM (III) ION, Retinoid isomerohydrolase
Authors:Kiser, P.D, Palczewski, K.
Deposit date:2012-05-09
Release date:2012-10-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of RPE65 isomerase in a lipidic matrix reveals roles for phospholipids and iron in catalysis.
Proc.Natl.Acad.Sci.USA, 109, 2012
4F3J
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BU of 4f3j by Molmil
Crystal Structure of Trimeric gC1q Domain of Human C1QTNF5 associated with Late-onset Retinal Macular Degeneration
Descriptor: Complement C1q tumor necrosis factor-related protein 5
Authors:Tu, X, Palczewski, K.
Deposit date:2012-05-09
Release date:2012-11-07
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.337 Å)
Cite:Crystal structure of the globular domain of C1QTNF5: Implications for late-onset retinal macular degeneration.
J.Struct.Biol., 180, 2012
4F30
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BU of 4f30 by Molmil
Structure of RPE65: P6522 crystal form grown in ammonium phosphate solution
Descriptor: FE (II) ION, PHOSPHATE ION, Retinoid isomerohydrolase
Authors:Kiser, P.D, Palczewski, K.
Deposit date:2012-05-08
Release date:2012-10-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structure of RPE65 isomerase in a lipidic matrix reveals roles for phospholipids and iron in catalysis.
Proc.Natl.Acad.Sci.USA, 109, 2012
7JTI
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BU of 7jti by Molmil
Interphotoreceptor retinoid-binding protein (IRBP) in complex with a monoclonal antibody (F3F5 mAb5)
Descriptor: Retinol-binding protein 3, mAb5 Fab heavy chain, mAb5 Fab light chain
Authors:Sears, A.E, Albiez, S, Gulati, S, Wang, B, Kiser, P, Kovacik, L, Engel, A, Stahlberg, H, Palczewski, K.
Deposit date:2020-08-17
Release date:2020-10-07
Last modified:2020-12-16
Method:ELECTRON MICROSCOPY (7.4 Å)
Cite:Single particle cryo-EM of the complex between interphotoreceptor retinoid-binding protein and a monoclonal antibody.
Faseb J., 34, 2020
7F1W
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BU of 7f1w by Molmil
X-ray crystal structure of visual arrestin complexed with inositol hexaphosphate
Descriptor: INOSITOL HEXAKISPHOSPHATE, S-arrestin
Authors:Kang, M, Jang, K, Eger, B.T, Ernst, O.P, Choe, H.W, Kim, Y.J.
Deposit date:2021-06-10
Release date:2021-10-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.097 Å)
Cite:Structural evidence for visual arrestin priming via complexation of phosphoinositols.
Structure, 30, 2022
7F1X
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BU of 7f1x by Molmil
X-ray crystal structure of visual arrestin complexed with inositol 1,4,5-triphosphate
Descriptor: 1,2-ETHANEDIOL, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, PENTANEDIAL, ...
Authors:Jang, K, Kang, M, Eger, B.T, Choe, H.W, Ernst, O.P, Kim, Y.J.
Deposit date:2021-06-10
Release date:2021-10-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural evidence for visual arrestin priming via complexation of phosphoinositols.
Structure, 30, 2022
2R2I
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BU of 2r2i by Molmil
Myristoylated Guanylate Cyclase Activating Protein-1 with Calcium Bound
Descriptor: BETA-MERCAPTOETHANOL, CALCIUM ION, Guanylyl cyclase-activating protein 1, ...
Authors:Stephen, R.
Deposit date:2007-08-25
Release date:2007-12-11
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Stabilizing function for myristoyl group revealed by the crystal structure of a neuronal calcium sensor, guanylate cyclase-activating protein 1.
Structure, 15, 2007
3QC9
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BU of 3qc9 by Molmil
Crystal structure of cross-linked bovine GRK1 T8C/N480C double mutant complexed with ADP and Mg
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
Authors:Huang, C.-C, Tesmer, J.J.G.
Deposit date:2011-01-15
Release date:2011-02-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Activation of G Protein-Coupled Receptor Kinase 1 Involves Interactions between Its N-Terminal Region and Its Kinase Domain.
Biochemistry, 50, 2011
2GGZ
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BU of 2ggz by Molmil
Crystal Structure of Human Guanylate Cyclase Activating Protein-3
Descriptor: CALCIUM ION, Guanylyl cyclase-activating protein 3
Authors:Stephen, R.
Deposit date:2006-03-24
Release date:2006-05-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Crystal Structure of GCAP3 Suggests Molecular Mechanism of GCAP-linked Cone Dystrophies.
J.Mol.Biol., 359, 2006
5ILO
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BU of 5ilo by Molmil
Crystal structure of photoreceptor dehydrogenase from Drosophila melanogaster
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Photoreceptor dehydrogenase, isoform C
Authors:Hofmann, L, Tsybovsky, Y, Banerjee, S.
Deposit date:2016-03-04
Release date:2016-11-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Structural Insights into the Drosophila melanogaster Retinol Dehydrogenase, a Member of the Short-Chain Dehydrogenase/Reductase Family.
Biochemistry, 55, 2016
5ILG
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BU of 5ilg by Molmil
Crystal structure of photoreceptor dehydrogenase from Drosophila melanogaster
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Hofmann, L, Tsybovsky, Y, Banerjee, S.
Deposit date:2016-03-04
Release date:2016-11-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Insights into the Drosophila melanogaster Retinol Dehydrogenase, a Member of the Short-Chain Dehydrogenase/Reductase Family.
Biochemistry, 55, 2016
3MZS
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BU of 3mzs by Molmil
Crystal Structure of Cytochrome P450 CYP11A1 in complex with 22-hydroxy-cholesterol
Descriptor: (3alpha,8alpha,22R)-cholest-5-ene-3,22-diol, Cholesterol side-chain cleavage enzyme, ISOPROPYL ALCOHOL, ...
Authors:Stout, C.D, Annalora, A, Mast, N, Pikuleva, I.
Deposit date:2010-05-12
Release date:2010-12-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Three-step Sequential Catalysis by the Cholesterol Side Chain Cleavage Enzyme CYP11A1.
J.Biol.Chem., 286, 2011
4DG1
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BU of 4dg1 by Molmil
Crystal structure of HIV-1 reverse transcriptase (RT) with polymorphism mutation K172A and K173A
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, MAGNESIUM ION, ...
Authors:Tu, X, Kirby, K.A, Marchand, B, Sarafianos, S.G.
Deposit date:2012-01-24
Release date:2012-06-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:HIV-1 Reverse Transcriptase (RT) Polymorphism 172K Suppresses the Effect of Clinically Relevant Drug Resistance Mutations to Both Nucleoside and Non-nucleoside RT Inhibitors.
J.Biol.Chem., 287, 2012
6C7K
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BU of 6c7k by Molmil
Crystal structure of an ACO/RPE65 chimera
Descriptor: Apocarotenoid-15,15'-oxygenase, CHLORIDE ION, FE (II) ION
Authors:Kiser, P.D, Shi, W.
Deposit date:2018-01-22
Release date:2018-04-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Insights into the pathogenesis of dominant retinitis pigmentosa associated with a D477G mutation in RPE65.
Hum.Mol.Genet., 27, 2018
6C7P
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BU of 6c7p by Molmil
Crystal structure of D477G ACO/RPE65 chimera, monoclinic crystal form
Descriptor: Apocarotenoid-15,15'-oxygenase, FE (II) ION
Authors:Kiser, P.D, Shi, W.
Deposit date:2018-01-23
Release date:2018-04-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Insights into the pathogenesis of dominant retinitis pigmentosa associated with a D477G mutation in RPE65.
Hum.Mol.Genet., 27, 2018

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