4F3J

Crystal Structure of Trimeric gC1q Domain of Human C1QTNF5 associated with Late-onset Retinal Macular Degeneration

Summary for 4F3J

Entry DOI	10.2210/pdb4f3j/pdb
Descriptor	Complement C1q tumor necrosis factor-related protein 5 (2 entities in total)
Functional Keywords	late-onset retinal macular degeneration, l-ormd, l-ord, amd, age-related macular degeneration, c1qtnf5, ctrp5, s163r, ser163arg, drusen, retinal deposites, 10-strand jelly-roll fold, mfrp, rpe, ciliary body, signaling protein
Biological source	Homo sapiens (human)
Cellular location	Secreted (Probable): Q9BXJ0
Total number of polymer chains	1
Total formula weight	16424.30
Authors	Tu, X.,Palczewski, K. (deposition date: 2012-05-09, release date: 2012-11-07, Last modification date: 2024-02-28)
Primary citation	Tu, X.,Palczewski, K. Crystal structure of the globular domain of C1QTNF5: Implications for late-onset retinal macular degeneration. J.Struct.Biol., 180:439-446, 2012 Cited by PubMed: 22892318 DOI: 10.1016/j.jsb.2012.07.011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.337 Å)

Structure validation