1WCO
 
 | | The solution structure of the nisin-lipid II complex | | Descriptor: | (2E,6E)-12-fluoro-11-(fluoromethyl)-3,7-dimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-alpha-muramic acid, ALA-FGA-LYS-DAL-DAL PEPTIDE, ... | | Authors: | Hsu, S.-T.D, Breukink, E, Tischenko, E, Lutters, M.A.G, de Kruijff, B, Kaptein, R, Bonvin, A.M.J.J, van Nuland, N.A.J. | | Deposit date: | 2004-11-19 | | Release date: | 2005-03-07 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | The nisin-lipid II complex reveals a pyrophosphate cage that provides a blueprint for novel antibiotics.
Nat. Struct. Mol. Biol., 11, 2004
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7YMV
 | | Cryo-EM structure of MERS-CoV spike protein, Two RBD-up conformation 1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Hsu, S.T.D, Chang, N.E, Weng, Z.W, Yang, T.J, Draczkowski, P. | | Deposit date: | 2022-07-29 | | Release date: | 2023-08-09 | | Last modified: | 2024-09-04 | | Method: | ELECTRON MICROSCOPY (6.74 Å) | | Cite: | Rapid simulation of glycoprotein structures by grafting and steric exclusion of glycan conformer libraries.
Cell, 187, 2024
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7YMW
 | | Cryo-EM structure of MERS-CoV spike protein, One RBD-up conformation 4 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | Authors: | Hsu, S.T.D, Chang, N.E, Weng, Z.W, Yang, T.J, Draczkowski, P. | | Deposit date: | 2022-07-29 | | Release date: | 2023-08-09 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (6.05 Å) | | Cite: | Rapid simulation of glycoprotein structures by grafting and steric exclusion of glycan conformer libraries.
Cell, 187, 2024
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7YMX
 | | Cryo-EM structure of MERS-CoV spike protein, One RBD-up conformation 2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | Authors: | Hsu, S.T.D, Chang, N.E, Weng, Z.W, Yang, T.J, Draczkowski, P. | | Deposit date: | 2022-07-29 | | Release date: | 2023-08-09 | | Last modified: | 2024-09-04 | | Method: | ELECTRON MICROSCOPY (4.44 Å) | | Cite: | Rapid simulation of glycoprotein structures by grafting and steric exclusion of glycan conformer libraries.
Cell, 187, 2024
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7YMT
 | | Cryo-EM structure of MERS-CoV spike protein, Two RBD-up conformation 2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | Authors: | Hsu, S.T.D, Chang, N.E, Weng, Z.W, Yang, T.J, Draczkowski, P. | | Deposit date: | 2022-07-29 | | Release date: | 2023-08-09 | | Last modified: | 2024-09-04 | | Method: | ELECTRON MICROSCOPY (6.55 Å) | | Cite: | Rapid simulation of glycoprotein structures by grafting and steric exclusion of glycan conformer libraries.
Cell, 187, 2024
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7YN0
 | | Cryo-EM structure of MERS-CoV spike protein, all RBD-down conformation | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Hsu, S.T.D, Chang, N.E, Weng, Z.W, Yang, T.J, Draczkowski, P. | | Deposit date: | 2022-07-29 | | Release date: | 2023-08-09 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Rapid simulation of glycoprotein structures by grafting and steric exclusion of glycan conformer libraries.
Cell, 187, 2024
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7YMY
 | | Cryo-EM structure of MERS-CoV spike protein, One RBD-up conformation 1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | Authors: | Hsu, S.T.D, Chang, N.E, Weng, Z.W, Yang, T.J, Draczkowski, P. | | Deposit date: | 2022-07-29 | | Release date: | 2023-08-09 | | Last modified: | 2024-09-04 | | Method: | ELECTRON MICROSCOPY (4.96 Å) | | Cite: | Rapid simulation of glycoprotein structures by grafting and steric exclusion of glycan conformer libraries.
Cell, 187, 2024
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7YMZ
 | | Cryo-EM structure of MERS-CoV spike protein, intermediate conformation | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | Authors: | Hsu, S.T.D, Chang, N.E, Weng, Z.W, Yang, T.J, Draczkowski, P. | | Deposit date: | 2022-07-29 | | Release date: | 2023-08-09 | | Last modified: | 2024-09-04 | | Method: | ELECTRON MICROSCOPY (4.39 Å) | | Cite: | Rapid simulation of glycoprotein structures by grafting and steric exclusion of glycan conformer libraries.
Cell, 187, 2024
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6JX7
 | | Cryo-EM structure of spike protein of feline infectious peritonitis virus strain UU4 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Feline Infectious Peritonitis Virus Spike Protein, ... | | Authors: | Hsu, S.T.D, Yang, T.J, Ko, T.P, Draczkowski, P. | | Deposit date: | 2019-04-22 | | Release date: | 2020-01-15 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.31 Å) | | Cite: | Cryo-EM analysis of a feline coronavirus spike protein reveals a unique structure and camouflaging glycans.
Proc.Natl.Acad.Sci.USA, 117, 2020
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7W6M
 | | Cryo-EM map of PEDV (Pintung 52) S protein with all three protomers in the D0-down conformation determined in situ on intact viral particles. | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Hsu, S.T.D, Draczkowski, P, Wang, Y.S. | | Deposit date: | 2021-12-02 | | Release date: | 2022-08-03 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (4.7 Å) | | Cite: | In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM.
Nat Commun, 13, 2022
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7W73
 | | Cryo-EM map of PEDV S protein with one protomer in the D0-up conformation while the other two in the D0-down conformation | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Hsu, S.T.D, Draczkowski, P, Wang, Y.S. | | Deposit date: | 2021-12-03 | | Release date: | 2022-08-03 | | Last modified: | 2022-12-21 | | Method: | ELECTRON MICROSCOPY (6.4 Å) | | Cite: | In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM.
Nat Commun, 13, 2022
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7Y6T
 | | Cryo-EM map of IPEC-J2 cell-derived PEDV PT52 S protein one D0-down and two D0-up | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Hsu, S.T.D, Draczkowski, P, Wang, Y.S. | | Deposit date: | 2022-06-21 | | Release date: | 2022-08-03 | | Last modified: | 2023-07-26 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM.
Nat Commun, 13, 2022
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7Y6U
 | | Symmetry-expanded and locally refined protomer structure of IPEC-J2 cell-derived PEDV PT52 S with a CTD-close conformation | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | Authors: | Hsu, S.T.D, Draczkowski, P, Wang, Y.S. | | Deposit date: | 2022-06-21 | | Release date: | 2022-08-03 | | Last modified: | 2022-09-14 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM.
Nat Commun, 13, 2022
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7Y6V
 | | Symmetry-expanded and locally refined protomer structure of IPEC-J2 cell-derived PEDV PT52 S with a CTD-open conformation | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Hsu, S.T.D, Draczkowski, P, Wang, Y.S. | | Deposit date: | 2022-06-21 | | Release date: | 2022-08-03 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM.
Nat Commun, 13, 2022
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7Y6S
 | | Cryo-EM map of IPEC-J2 cell-derived PEDV PT52 S protein with three D0-up | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Hsu, S.T.D, Draczkowski, P, Wang, Y.S. | | Deposit date: | 2022-06-21 | | Release date: | 2022-08-03 | | Last modified: | 2022-09-14 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM.
Nat Commun, 13, 2022
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2BUN
 | | Solution structure of the BLUF domain of AppA 5-125 | | Descriptor: | APPA, FLAVIN-ADENINE DINUCLEOTIDE | | Authors: | Grinstead, J.S, Hsu, S.-T, Laan, W, Bonvin, A.M.J.J, Hellingwerf, K.J, Boelens, R, Kaptein, R. | | Deposit date: | 2005-06-15 | | Release date: | 2005-12-07 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | The solution structure of the AppA BLUF domain: insight into the mechanism of light-induced signaling.
Chembiochem, 7, 2006
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1W9N
 | | Isolation and characterization of epilancin 15X, a novel antibiotic from a clinical strain of Staphylococcus epidermidis | | Descriptor: | EPILANCIN 15X | | Authors: | Ekkelenkamp, M, Hanssen, M.G.M, Hsu, S.-T.D, de Jong, A, Milatovic, D, Verhoef, J, van Nuland, N.A.J. | | Deposit date: | 2004-10-14 | | Release date: | 2005-04-01 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Isolation and structural characterization of epilancin 15X, a novel lantibiotic from a clinical strain of Staphylococcus epidermidis.
FEBS Lett., 579, 2005
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5H9P
 | | Crystal Structure of Human Galectin-3 CRD in Complex with TD139 | | Descriptor: | 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside, Galectin-3 | | Authors: | Hsieh, T.J, Lin, H.Y, Lin, C.H. | | Deposit date: | 2015-12-29 | | Release date: | 2016-06-29 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors
Sci Rep, 6, 2016
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4W4S
 | | Crystal structure of ent-kaurene synthase BJKS from bradyrhizobium japonicum in complex with BPH-629 | | Descriptor: | Uncharacterized protein blr2150, [2-(3-DIBENZOFURAN-4-YL-PHENYL)-1-HYDROXY-1-PHOSPHONO-ETHYL]-PHOSPHONIC ACID | | Authors: | Liu, W, Zheng, Y, Huang, C.H, Guo, R.T. | | Deposit date: | 2014-08-15 | | Release date: | 2015-01-14 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure, function and inhibition of ent-kaurene synthase from Bradyrhizobium japonicum.
Sci Rep, 4, 2014
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4W4R
 | | Crystal structure of ent-kaurene synthase BJKS from bradyrhizobium japonicum | | Descriptor: | Uncharacterized protein blr2150 | | Authors: | Liu, W, Zheng, Y, Huang, C.H, Ko, T.P, Guo, R.T. | | Deposit date: | 2014-08-15 | | Release date: | 2015-01-14 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Structure, function and inhibition of ent-kaurene synthase from Bradyrhizobium japonicum.
Sci Rep, 4, 2014
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8J0A
 | | Robust design of effective allosteric activator UbV R4 for Rsp5 E3 ligase using the machine-learning tool ProteinMPNN | | Descriptor: | SULFATE ION, Ubiquitin variant R4 | | Authors: | Lin, Y.-F, Hsieh, Y.-J, Kao, H.-W, Ko, T.-P, Wu, K.-P. | | Deposit date: | 2023-04-10 | | Release date: | 2023-08-09 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Robust Design of Effective Allosteric Activators for Rsp5 E3 Ligase Using the Machine Learning Tool ProteinMPNN.
Acs Synth Biol, 12, 2023
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2M87
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5H9S
 | | Crystal Structure of Human Galectin-7 in Complex with TAZTDG | | Descriptor: | (2~{S},3~{R},4~{S},5~{R},6~{R})-2-[(2~{S},3~{R},4~{S},5~{R},6~{R})-4-[4-(3-fluorophenyl)-1,2,3-triazol-1-yl]-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]sulfanyl-6-(hydroxymethyl)oxane-3,4,5-triol, Galectin-7 | | Authors: | Hsieh, T.J, Lin, H.Y, Lin, C.H. | | Deposit date: | 2015-12-29 | | Release date: | 2016-06-29 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.821 Å) | | Cite: | Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors
Sci Rep, 6, 2016
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5H9Q
 | | Crystal Structure of Human Galectin-7 in Complex with TD139 | | Descriptor: | 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside, Galectin-7 | | Authors: | Hsieh, T.J, Lin, H.Y, Lin, C.H. | | Deposit date: | 2015-12-29 | | Release date: | 2016-06-29 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.931 Å) | | Cite: | Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors
Sci Rep, 6, 2016
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5H9R
 | | Crystal Structure of Human Galectin-3 CRD in Complex with TAZTDG | | Descriptor: | (2~{S},3~{R},4~{S},5~{R},6~{R})-2-[(2~{S},3~{R},4~{S},5~{R},6~{R})-4-[4-(3-fluorophenyl)-1,2,3-triazol-1-yl]-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]sulfanyl-6-(hydroxymethyl)oxane-3,4,5-triol, Galectin-3 | | Authors: | Hsieh, T.J, Lin, H.Y, Lin, C.H. | | Deposit date: | 2015-12-29 | | Release date: | 2016-06-29 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors
Sci Rep, 6, 2016
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