8J0A
Robust design of effective allosteric activator UbV R4 for Rsp5 E3 ligase using the machine-learning tool ProteinMPNN
Summary for 8J0A
| Entry DOI | 10.2210/pdb8j0a/pdb |
| Descriptor | Ubiquitin variant R4, SULFATE ION (3 entities in total) |
| Functional Keywords | ubiquitin variant, deep-learning, biosynthetic protein |
| Biological source | synthetic construct |
| Total number of polymer chains | 2 |
| Total formula weight | 23620.53 |
| Authors | Lin, Y.-F.,Hsieh, Y.-J.,Kao, H.-W.,Ko, T.-P.,Wu, K.-P. (deposition date: 2023-04-10, release date: 2023-08-09, Last modification date: 2023-08-30) |
| Primary citation | Kao, H.W.,Lu, W.L.,Ho, M.R.,Lin, Y.F.,Hsieh, Y.J.,Ko, T.P.,Danny Hsu, S.T.,Wu, K.P. Robust Design of Effective Allosteric Activators for Rsp5 E3 Ligase Using the Machine Learning Tool ProteinMPNN. Acs Synth Biol, 12:2310-2319, 2023 Cited by PubMed: 37556858DOI: 10.1021/acssynbio.3c00042 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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