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3Q0Y
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BU of 3q0y by Molmil
N-terminal domain of C. reinhardtii SAS-6 homolog Bld12p
Descriptor: Centriole protein
Authors:Kitagawa, D, Vakonakis, I, Olieric, N, Hilbert, M, Keller, D, Olieric, V, Bortfeld, M, Erat, M.C, Flueckiger, I, Goenczy, P, Steinmetz, M.O.
Deposit date:2010-12-16
Release date:2011-02-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of the 9-fold symmetry of centrioles.
Cell(Cambridge,Mass.), 144, 2011
3RDV
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BU of 3rdv by Molmil
Structure of the SLAIN2c-CLIPCG1 complex
Descriptor: BETA-MERCAPTOETHANOL, CAP-Gly domain-containing linker protein 1, SLAIN motif-containing protein 2, ...
Authors:Manatschal, C, Olieric, V, Steinmetz, M.O.
Deposit date:2011-04-01
Release date:2011-06-29
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase
J.Cell Biol., 193, 2011
5DCY
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BU of 5dcy by Molmil
Iridoid synthase G150A mutant from Catharanthus roseus - binary complex with NADP+
Descriptor: 1,2-ETHANEDIOL, Iridoid synthase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Caputi, L, Kries, H, Stevenson, C.E.M, Kamileen, M.O, Sherden, N.H, Geu-Flores, F, Lawson, D.M, O'Connor, S.E.
Deposit date:2015-08-24
Release date:2015-10-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural determinants of reductive terpene cyclization in iridoid biosynthesis.
Nat.Chem.Biol., 12, 2016
5LB7
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BU of 5lb7 by Molmil
Complex structure between p60N/p80C katanin and a peptide derived from ASPM
Descriptor: Abnormal spindle-like microcephaly-associated protein homolog, Katanin p60 ATPase-containing subunit A1, Katanin p80 WD40 repeat-containing subunit B1
Authors:Rezabkova, L, Capitani, G, Kammerer, R.A, Steinmetz, M.O.
Deposit date:2016-06-15
Release date:2017-04-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex.
Nat. Cell Biol., 19, 2017
5LA6
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BU of 5la6 by Molmil
Tubulin-pironetin complex
Descriptor: CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Prota, A.E, Setter, J, Waight, A.B, Bargsten, K, Murga, J, Diaz, J.F, Steinmetz, M.O.
Deposit date:2016-06-13
Release date:2016-07-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Pironetin Binds Covalently to alpha Cys316 and Perturbs a Major Loop and Helix of alpha-Tubulin to Inhibit Microtubule Formation.
J.Mol.Biol., 428, 2016
5DCU
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BU of 5dcu by Molmil
Iridoid synthase from Catharanthus roseus - ternary complex with NADP+ and triethylene glycol carboxylic acid
Descriptor: 1,2-ETHANEDIOL, Iridoid synthase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Caputi, L, Kries, H, Stevenson, C.E.M, Kamileen, M.O, Sherden, N.H, Geu-Flores, F, Lawson, D.M, O'Connor, S.E.
Deposit date:2015-08-24
Release date:2015-10-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural determinants of reductive terpene cyclization in iridoid biosynthesis.
Nat.Chem.Biol., 12, 2016
3Q0X
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BU of 3q0x by Molmil
N-terminal coiled-coil dimer domain of C. reinhardtii SAS-6 homolog Bld12p
Descriptor: Centriole protein
Authors:Kitagawa, D, Vakonakis, I, Olieric, N, Hilbert, M, Keller, D, Olieric, V, Bortfeld, M, Erat, M.C, Flueckiger, I, Goenczy, P, Steinmetz, M.O.
Deposit date:2010-12-16
Release date:2011-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.02 Å)
Cite:Structural basis of the 9-fold symmetry of centrioles.
Cell(Cambridge,Mass.), 144, 2011
3RDE
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BU of 3rde by Molmil
Crystal structure of the catalytic domain of porcine leukocyte 12-lipoxygenase
Descriptor: 3-{4-[(tridec-2-yn-1-yloxy)methyl]phenyl}propanoic acid, Arachidonate 12-lipoxygenase, 12S-type, ...
Authors:Funk, M.O, Xu, S, Marnett, L.J, Mueser, T.C.
Deposit date:2011-04-01
Release date:2012-04-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.892 Å)
Cite:Crystal structure of 12-lipoxygenase catalytic-domain-inhibitor complex identifies a substrate-binding channel for catalysis.
Structure, 20, 2012
5LOV
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BU of 5lov by Molmil
DZ-2384 tubulin complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, DZ 2384, ...
Authors:Prota, A.E, Steinmetz, M.O, Shore, G.C, Brouhard, G, Roulston, A.
Deposit date:2016-08-10
Release date:2016-11-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity.
Sci Transl Med, 8, 2016
5LXS
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BU of 5lxs by Molmil
Tubulin-KS-1-199-32 complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Prota, A.E, Steinmetz, M.O.
Deposit date:2016-09-22
Release date:2017-09-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis of Microtubule Stabilization by Discodermolide.
Chembiochem, 18, 2017
5D3A
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BU of 5d3a by Molmil
KIF21A regulatory coiled coil
Descriptor: GLYCEROL, Kinesin-like protein KIF21A
Authors:Bianchi, S, Kraatz, S, Steinmetz, M.O, Kammerer, A.R.
Deposit date:2015-08-06
Release date:2016-09-14
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.495 Å)
Cite:Structure of KIF21A regulatory coiled coil
To Be Published
5LZN
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BU of 5lzn by Molmil
-TIP microtubule-binding domain
Descriptor: Calmodulin-regulated spectrin-associated protein 3
Authors:Stangier, M.M, Steinmetz, M.O.
Deposit date:2016-09-30
Release date:2017-10-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A structural model for microtubule minus-end recognition and protection by CAMSAP proteins.
Nat. Struct. Mol. Biol., 24, 2017
5DCW
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BU of 5dcw by Molmil
Iridoid synthase from Catharanthus roseus - ligand free structure
Descriptor: 1,2-ETHANEDIOL, Iridoid synthase
Authors:Caputi, L, Kries, H, Stevenson, C.E.M, Kamileen, M.O, Sherden, N.H, Geu-Flores, F, Lawson, D.M, O'Connor, S.E.
Deposit date:2015-08-24
Release date:2015-10-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural determinants of reductive terpene cyclization in iridoid biosynthesis.
Nat.Chem.Biol., 12, 2016
5FCM
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BU of 5fcm by Molmil
CrBld10-N 1-70
Descriptor: Basal body protein, ISOPROPYL ALCOHOL, SULFATE ION
Authors:Kraatz, S.H.W, Steinmetz, M.O.
Deposit date:2015-12-15
Release date:2016-07-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.229 Å)
Cite:The Human Centriolar Protein CEP135 Contains a Two-Stranded Coiled-Coil Domain Critical for Microtubule Binding.
Structure, 24, 2016
3REE
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BU of 3ree by Molmil
Crystal structure of mitoNEET
Descriptor: CDGSH iron-sulfur domain-containing protein 1, FE2/S2 (INORGANIC) CLUSTER
Authors:Funk, M.O, Arif, W, Xu, S, Mueser, T.C.
Deposit date:2011-04-04
Release date:2011-04-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Complexes of the Outer Mitochondrial Membrane Protein MitoNEET with Resveratrol-3-Sulfate.
Biochemistry, 50, 2011
4I4T
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BU of 4i4t by Molmil
Crystal structure of tubulin-RB3-TTL-Zampanolide complex
Descriptor: (2Z,4E)-N-[(S)-[(1S,2E,5S,8E,10Z,17S)-3,11-dimethyl-19-methylidene-7,13-dioxo-6,21-dioxabicyclo[15.3.1]henicosa-2,8,10-trien-5-yl](hydroxy)methyl]hexa-2,4-dienamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Prota, A.E, Steinmetz, M.O.
Deposit date:2012-11-28
Release date:2013-01-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents.
Science, 339, 2013
1D7M
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BU of 1d7m by Molmil
COILED-COIL DIMERIZATION DOMAIN FROM CORTEXILLIN I
Descriptor: CORTEXILLIN I
Authors:Burkhard, P, Kammerer, R.A, Steinmetz, M.O, Bourenkov, G.P, Aebi, U.
Deposit date:1999-10-19
Release date:2000-03-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The coiled-coil trigger site of the rod domain of cortexillin I unveils a distinct network of interhelical and intrahelical salt bridges.
Structure Fold.Des., 8, 2000
5FIQ
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BU of 5fiq by Molmil
Exonuclease domain-containing 1 (Exd1) in the native conformation
Descriptor: EXD1
Authors:Yang, Z, Chen, K.M, Pandey, R.R, Homolka, D, Reuter, M, Rodino Janeiro, B.K, Sachidanandam, R, Fauvarque, M.O, McCarthy, A.A, Pillai, R.S.
Deposit date:2015-10-01
Release date:2015-12-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Piwi Slicing and Exd1 Drive Biogenesis of Nuclear Pirnas from Cytosolic Targets of the Mouse Pirna Pathway
Mol.Cell, 61, 2016
2TGD
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BU of 2tgd by Molmil
LACK OF THE TRANSITION STATE STABILIZATION SITE IS A FACTOR IN THE INACTIVITY OF TRYPSINOGEN, A SERINE PROTEASE ZYMOGEN. STRUCTURE OF DFP INHIBITED BOVINE TRYPSINOGEN AT 2.1 ANGSTROMS RESOLUTION
Descriptor: CALCIUM ION, DIISOPROPYL PHOSPHONATE, TRYPSINOGEN
Authors:Jones, M.O, Stroud, R.M.
Deposit date:1986-03-17
Release date:1986-05-07
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Lack of the Transition State Stabilization Site is a Factor in the Inactivity of Trypsinogen, a Serine Protease Zymogen. Structure of Dfp Inhibited Bovine Trypsinogen at 2.1 Angstroms Resolution
To be Published
2WKK
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BU of 2wkk by Molmil
Identification of the glycan target of the nematotoxic fungal galectin CGL2 in Caenorhabditis elegans
Descriptor: GALECTIN-2, GLYCEROL, MAGNESIUM ION, ...
Authors:Butschi, A, Titz, A, Waelti, M, Olieric, V, Paschinger, K, Xiaoqiang, G, Seeberger, P.H, Wilson, I.B.H, Aebi, M, Hengartner, M.O, Kuenzler, M.
Deposit date:2009-06-14
Release date:2010-01-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Caenorhabditis Elegans N-Glycan Core Beta-Galactoside Confers Sensitivity Towards Nematotoxic Fungal Galectin Cgl2.
Plos Pathog., 6, 2010
5IN7
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BU of 5in7 by Molmil
X-RAY STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN
Descriptor: Neuronal migration protein doublecortin
Authors:Ruf, A, Benz, J, Burger, D, D'Arcy, B, Debulpaep, M, Di Lello, P, Fry, D, Huber, W, Kremer, T, Laeremans, T, Matile, H, Ross, A, Rudolph, M.G, Rufer, A.C, Sharma, A, Steinmetz, M.O, Steyaert, J, Schoch, G, Stihle, M, Thoma, R.
Deposit date:2016-03-07
Release date:2016-03-23
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies.
J.Biol.Chem., 291, 2016
5IOI
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BU of 5ioi by Molmil
X-RAY STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN
Descriptor: Neuronal migration protein doublecortin
Authors:Ruf, A, Benz, J, Burger, D, D'Arcy, B, Debulpaep, M, Di Lello, P, Fry, D, Huber, W, Kremer, T, Laeremans, T, Matile, H, Ross, A, Rudolph, M.G, Rufer, A.C, Sharma, A, Steinmetz, M.O, Steyaert, J, Schoch, G, Stihle, M, Thoma, R.
Deposit date:2016-03-08
Release date:2016-03-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies.
J.Biol.Chem., 291, 2016
5IO9
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BU of 5io9 by Molmil
X-RAY STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN
Descriptor: Neuronal migration protein doublecortin
Authors:Ruf, A, Benz, J, Burger, D, D'Arcy, B, Debulpaep, M, Di Lello, P, Fry, D, Huber, W, Kremer, T, Laeremans, T, Matile, H, Ross, A, Rudolph, M.G, Rufer, A.C, Sharma, A, Steinmetz, M.O, Steyaert, J, Schoch, G, Stihle, M, Thoma, R.
Deposit date:2016-03-08
Release date:2016-03-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies.
J.Biol.Chem., 291, 2016
5IP4
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BU of 5ip4 by Molmil
X-RAY STRUCTURE OF THE C-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN
Descriptor: Neuronal migration protein doublecortin, XA4551 NANOBODY AGAINST C-DCX
Authors:Ruf, A, Benz, J, Burger, D, D'Arcy, B, Debulpaep, M, Di Lello, P, Fry, D, Huber, W, Kremer, T, Laeremans, T, Matile, H, Ross, A, Rudolph, M.G, Rufer, A.C, Sharma, A, Steinmetz, M.O, Steyaert, J, Schoch, G, Stihle, M, Thoma, R.
Deposit date:2016-03-09
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies.
J.Biol.Chem., 291, 2016
5ITZ
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BU of 5itz by Molmil
Crystal structure of the SAC domain of CPAP in a complex with Tubulin and Darpin
Descriptor: Centromere protein J, Designed ankyrin repeat protein (DARPIN) D1, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Sharma, A, Steinmetz, M.O.
Deposit date:2016-03-17
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Centriolar CPAP/SAS-4 Imparts Slow Processive Microtubule Growth.
Dev.Cell, 37, 2016

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