3RDE
Crystal structure of the catalytic domain of porcine leukocyte 12-lipoxygenase
Summary for 3RDE
Entry DOI | 10.2210/pdb3rde/pdb |
Descriptor | Arachidonate 12-lipoxygenase, 12S-type, POTASSIUM ION, FE (II) ION, ... (5 entities in total) |
Functional Keywords | lipoxygenase, c-terminal domain, protein-inhibitor complex, 4-(2-oxapentadeca-4-yne)phenylpropanoic acid, lipoxygenase catalytic domain, dioxygenase, fe, leukocyte, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Sus scrofa (pigs,swine,wild boar) |
Cellular location | Cytoplasm: P16469 |
Total number of polymer chains | 4 |
Total formula weight | 260800.54 |
Authors | Funk, M.O.,Xu, S.,Marnett, L.J.,Mueser, T.C. (deposition date: 2011-04-01, release date: 2012-04-18, Last modification date: 2023-09-13) |
Primary citation | Xu, S.,Mueser, T.C.,Marnett, L.J.,Funk, M.O. Crystal structure of 12-lipoxygenase catalytic-domain-inhibitor complex identifies a substrate-binding channel for catalysis. Structure, 20:1490-1497, 2012 Cited by PubMed: 22795085DOI: 10.1016/j.str.2012.06.003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.892 Å) |
Structure validation
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