6TJ5
| T. gondii myosin A trimeric complex with ELC1 | Descriptor: | CALCIUM ION, CHLORIDE ION, Calmodulin, ... | Authors: | Pazicky, S, Loew, C. | Deposit date: | 2019-11-25 | Release date: | 2020-10-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.394 Å) | Cite: | Structural role of essential light chains in the apicomplexan glideosome. Commun Biol, 3, 2020
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6GS1
| Crystal structure of peptide transporter DtpA-nanobody in MES buffer | Descriptor: | Dipeptide and tripeptide permease A, Nanobody 00 | Authors: | Ural-Blimke, Y, Flayhan, A, Loew, C, Quistgaard, E.M. | Deposit date: | 2018-06-13 | Release date: | 2019-01-30 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.29 Å) | Cite: | Structure of Prototypic Peptide Transporter DtpA from E. coli in Complex with Valganciclovir Provides Insights into Drug Binding of Human PepT1. J. Am. Chem. Soc., 141, 2019
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6GS4
| Crystal structure of peptide transporter DtpA-nanobody in complex with valganciclovir | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Dipeptide and tripeptide permease A, [(2~{S})-2-[(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)methoxy]-3-oxidanyl-propyl] (2~{S})-2-azanyl-3-methyl-butanoate, ... | Authors: | Ural-Blimke, Y, Flayhan, A, Quistgaard, E.M, Loew, C. | Deposit date: | 2018-06-13 | Release date: | 2019-01-30 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.645 Å) | Cite: | Structure of Prototypic Peptide Transporter DtpA from E. coli in Complex with Valganciclovir Provides Insights into Drug Binding of Human PepT1. J. Am. Chem. Soc., 141, 2019
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6GS7
| Crystal structure of peptide transporter DtpA-nanobody in glycine buffer | Descriptor: | Dipeptide and tripeptide permease A, nanobody | Authors: | Ural-Blimke, Y, Flayhan, A, Quistgaard, E.M, Loew, C. | Deposit date: | 2018-06-13 | Release date: | 2019-01-30 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structure of Prototypic Peptide Transporter DtpA from E. coli in Complex with Valganciclovir Provides Insights into Drug Binding of Human PepT1. J. Am. Chem. Soc., 141, 2019
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6GHJ
| PepTSt in complex with tripeptide Phe-Ala-Gln | Descriptor: | (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Martinez Molledo, M, Quistgaard, E.M, Loew, C. | Deposit date: | 2018-05-08 | Release date: | 2018-09-19 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Tripeptide binding in a proton-dependent oligopeptide transporter. FEBS Lett., 592, 2018
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6ZN3
| Plasmodium facliparum glideosome trimeric sub-complex | Descriptor: | Myosin A tail domain interacting protein, Myosin essential light chain ELC, Myosin-A | Authors: | Pazicky, S, Loew, C. | Deposit date: | 2020-07-06 | Release date: | 2020-10-21 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structural role of essential light chains in the apicomplexan glideosome. Commun Biol, 3, 2020
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6EIA
| PepTSt in complex with HEPES (100 mM) | Descriptor: | (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Martinez Molledo, M, Quistgaard, E.M, Loew, C. | Deposit date: | 2017-09-18 | Release date: | 2018-02-21 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Multispecific Substrate Recognition in a Proton-Dependent Oligopeptide Transporter. Structure, 26, 2018
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7OXG
| ttSlyD FKBP domain with M8A pseudo-wild-type S2 peptide | Descriptor: | 30S ribosomal protein S2, CHLORIDE ION, IMIDAZOLE, ... | Authors: | Pazicky, S, Lei, J, Loew, C. | Deposit date: | 2021-06-22 | Release date: | 2022-03-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Impact of distant peptide substrate residues on enzymatic activity of SlyD. Cell.Mol.Life Sci., 79, 2022
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7OXH
| ttSlyD with pseudo-wild-type S2 peptide | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 30S ribosomal protein S2, CHLORIDE ION, ... | Authors: | Pazicky, S, Lei, J, Loew, C. | Deposit date: | 2021-06-22 | Release date: | 2022-03-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Impact of distant peptide substrate residues on enzymatic activity of SlyD. Cell.Mol.Life Sci., 79, 2022
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7OXI
| ttSlyD with W4A pseudo-wild-type S2 peptide | Descriptor: | 30S ribosomal protein S2, CHLORIDE ION, Peptidyl-prolyl cis-trans isomerase | Authors: | Pazicky, S, Lei, J, Loew, C. | Deposit date: | 2021-06-22 | Release date: | 2022-03-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Impact of distant peptide substrate residues on enzymatic activity of SlyD. Cell.Mol.Life Sci., 79, 2022
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7OXK
| ttSlyD with W4K pseudo-wild-type S2 peptide | Descriptor: | 30S ribosomal protein S2, Peptidyl-prolyl cis-trans isomerase | Authors: | Pazicky, S, Lei, J, Loew, C. | Deposit date: | 2021-06-22 | Release date: | 2022-03-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Impact of distant peptide substrate residues on enzymatic activity of SlyD. Cell.Mol.Life Sci., 79, 2022
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7OXJ
| ttSlyD with M8A pseudo-wild-type S2 peptide | Descriptor: | 30S ribosomal protein S2, CHLORIDE ION, Fragment of 30S ribosomal protein S2 peptide, ... | Authors: | Pazicky, S, Lei, J, Loew, C. | Deposit date: | 2021-06-22 | Release date: | 2022-03-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Impact of distant peptide substrate residues on enzymatic activity of SlyD. Cell.Mol.Life Sci., 79, 2022
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7PMW
| HsPepT1 bound to Ala-Phe in the outward facing occluded conformation | Descriptor: | ALA-PHE, Solute carrier family 15 member 1 | Authors: | Killer, M, Wald, J, Pieprzyk, J, Marlovits, T.C, Loew, C. | Deposit date: | 2021-09-03 | Release date: | 2021-10-20 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural snapshots of human PepT1 and PepT2 reveal mechanistic insights into substrate and drug transport across epithelial membranes. Sci Adv, 7, 2021
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7PMX
| HsPepT1 bound to Ala-Phe in the outward facing open conformation | Descriptor: | ALA-PHE, Solute carrier family 15 member 1 | Authors: | Killer, M, Wald, J, Pieprzyk, J, Marlovits, T.C, Loew, C. | Deposit date: | 2021-09-03 | Release date: | 2021-10-20 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural snapshots of human PepT1 and PepT2 reveal mechanistic insights into substrate and drug transport across epithelial membranes. Sci Adv, 7, 2021
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7PMY
| HsPepT2 bound to Ala-Phe in the inward facing partially occluded conformation | Descriptor: | ALA-PHE, Solute carrier family 15 member 2 | Authors: | Killer, M, Wald, J, Pieprzyk, J, Marlovits, T.C, Loew, C. | Deposit date: | 2021-09-04 | Release date: | 2021-10-20 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural snapshots of human PepT1 and PepT2 reveal mechanistic insights into substrate and drug transport across epithelial membranes. Sci Adv, 7, 2021
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7PN1
| Apo HsPepT1 in the outward facing open conformation | Descriptor: | Solute carrier family 15 member 1 | Authors: | Killer, M, Wald, J, Pieprzyk, J, Marlovits, T.C, Loew, C. | Deposit date: | 2021-09-04 | Release date: | 2021-10-20 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural snapshots of human PepT1 and PepT2 reveal mechanistic insights into substrate and drug transport across epithelial membranes. Sci Adv, 7, 2021
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5OXN
| PepTSt in complex with dipeptide Phe-Ala | Descriptor: | (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ALANINE, ... | Authors: | Martinez Molledo, M, Quistgaard, E.M, Loew, C. | Deposit date: | 2017-09-07 | Release date: | 2018-02-21 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.196 Å) | Cite: | Multispecific Substrate Recognition in a Proton-Dependent Oligopeptide Transporter. Structure, 26, 2018
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5OXO
| PepTSt apo structure | Descriptor: | (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, CITRIC ACID, ... | Authors: | Martinez Molledo, M, Quistgaard, E.M, Loew, C. | Deposit date: | 2017-09-07 | Release date: | 2018-02-21 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Multispecific Substrate Recognition in a Proton-Dependent Oligopeptide Transporter. Structure, 26, 2018
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5OXP
| PepTSt in occluded conformation with phosphate ion bound | Descriptor: | (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, Di-or tripeptide:H+ symporter, ... | Authors: | Martinez Molledo, M, Quistgaard, E.M, Loew, C. | Deposit date: | 2017-09-07 | Release date: | 2018-02-21 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.372 Å) | Cite: | Multispecific Substrate Recognition in a Proton-Dependent Oligopeptide Transporter. Structure, 26, 2018
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5OXK
| PepTSt in complex with dipeptide Ala-Gln | Descriptor: | (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ALANINE, ... | Authors: | Martinez Molledo, M, Quistgaard, E.M, Loew, C. | Deposit date: | 2017-09-07 | Release date: | 2018-02-21 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Multispecific Substrate Recognition in a Proton-Dependent Oligopeptide Transporter. Structure, 26, 2018
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5OXQ
| PepTSt in complex with HEPES (300 mM) | Descriptor: | (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Martinez Molledo, M, Quistgaard, E.M, Loew, C. | Deposit date: | 2017-09-07 | Release date: | 2018-02-21 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.195 Å) | Cite: | Multispecific Substrate Recognition in a Proton-Dependent Oligopeptide Transporter. Structure, 26, 2018
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5OXM
| PepTSt in complex with dipeptide Asp-Glu | Descriptor: | (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ASPARTIC ACID, ... | Authors: | Martinez Molledo, M, Quistgaard, E.M, Loew, C. | Deposit date: | 2017-09-07 | Release date: | 2018-02-21 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.295 Å) | Cite: | Multispecific Substrate Recognition in a Proton-Dependent Oligopeptide Transporter. Structure, 26, 2018
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5OXL
| PepTSt in complex with dipeptide Ala-Leu | Descriptor: | (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Martinez Molledo, M, Quistgaard, E.M, Loew, C. | Deposit date: | 2017-09-07 | Release date: | 2018-02-21 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.66 Å) | Cite: | Multispecific Substrate Recognition in a Proton-Dependent Oligopeptide Transporter. Structure, 26, 2018
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6YAU
| CRYSTAL STRUCTURE OF ASGPR 1 IN COMPLEX WITH GN-A. | Descriptor: | 5-[(2~{R},3~{R},4~{R},5~{R},6~{R})-3-acetamido-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-yl]oxy-~{N}-[3-(propanoylamino)propyl]pentanamide, Asialoglycoprotein receptor 1, CALCIUM ION | Authors: | Schreuder, H.A, Liesum, A. | Deposit date: | 2020-03-13 | Release date: | 2021-01-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.397 Å) | Cite: | Triantennary GalNAc Molecular Imaging Probes for Monitoring Hepatocyte Function in a Rat Model of Nonalcoholic Steatohepatitis. Adv Sci, 7, 2020
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6YG9
| CRYSTAL STRUCTURE OF HUMAN SERUM ALBUMIN (HSA) IN COMPLEX WITH GN-07. | Descriptor: | 20-[[(2~{S})-5-[2-[2-[2-[2-[2-[2-(diethylamino)-2-oxidanylidene-ethoxy]ethoxy]ethylamino]-2-oxidanylidene-ethoxy]ethoxy]ethylamino]-1-oxidanyl-1,5-bis(oxidanylidene)pentan-2-yl]amino]-20-oxidanylidene-icosanoic acid, MYRISTIC ACID, Serum albumin | Authors: | Schreuder, H.A, Liesum, A. | Deposit date: | 2020-03-27 | Release date: | 2021-01-13 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Triantennary GalNAc Molecular Imaging Probes for Monitoring Hepatocyte Function in a Rat Model of Nonalcoholic Steatohepatitis. Adv Sci, 7, 2020
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