4XCN
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![BU of 4xcn by Molmil](/molmil-images/mine/4xcn) | Crystal structure of human 4E10 Fab in complex with phosphatidic acid (06:0 PA); 2.9 A resolution | Descriptor: | (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 4E10 Fab heavy chain, 4E10 Fab light chain, ... | Authors: | Irimia, A, Stanfield, R.L, Wilson, I.A. | Deposit date: | 2014-12-18 | Release date: | 2016-02-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10. Immunity, 44, 2016
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8HSK
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5MNI
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![BU of 5mni by Molmil](/molmil-images/mine/5mni) | Escherichia coli AGPase mutant R130A apo form | Descriptor: | Glucose-1-phosphate adenylyltransferase | Authors: | Cifuente, J.O, Comino, N, Marina, A, Orrantia, A, Eguskiza, A, Guerin, M.E. | Deposit date: | 2016-12-13 | Release date: | 2017-03-01 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3.09 Å) | Cite: | Mechanistic insights into the allosteric regulation of bacterial ADP-glucose pyrophosphorylases. J. Biol. Chem., 292, 2017
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8HTT
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![BU of 8htt by Molmil](/molmil-images/mine/8htt) | Cryo-EM structure of human TMEM87A, gluconate-bound | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, D-gluconic acid, Transmembrane protein 87A,EGFP, ... | Authors: | Han, A, Kim, H.M. | Deposit date: | 2022-12-21 | Release date: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structure of human TMEM87A, PE-bound To Be Published
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8DD8
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![BU of 8dd8 by Molmil](/molmil-images/mine/8dd8) | PI 3-kinase alpha with nanobody 3-142, crosslinked with DSG | Descriptor: | Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Authors: | Hart, J.R, Liu, X, Pan, C, Liang, A, Ueno, L, Xu, Y, Quezada, A, Zou, X, Yang, S, Zhou, Q, Schoonooghe, S, Hassanzadeh-Ghassabeh, G, Xia, T, Shui, W, Yang, D, Vogt, P.K, Wang, M.-W. | Deposit date: | 2022-06-17 | Release date: | 2022-09-21 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Nanobodies and chemical cross-links advance the structural and functional analysis of PI3K alpha. Proc.Natl.Acad.Sci.USA, 119, 2022
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8HSI
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![BU of 8hsi by Molmil](/molmil-images/mine/8hsi) | Cryo-EM structure of human TMEM87A, PE-bound | Descriptor: | (1S)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | Authors: | Han, A, Kim, H.M. | Deposit date: | 2022-12-19 | Release date: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cryo-EM structure of human TMEM87A, PE-bound To Be Published
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8HUC
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![BU of 8huc by Molmil](/molmil-images/mine/8huc) | Crystal structure of PaIch (Pec1) | Descriptor: | GLYCEROL, MaoC_dehydrat_N domain-containing protein, NITRATE ION | Authors: | Pramanik, A, Datta, S. | Deposit date: | 2022-12-23 | Release date: | 2023-12-27 | Last modified: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.984 Å) | Cite: | Structural and functional insights of itaconyl-CoA hydratase from Pseudomonas aeruginosa highlight a novel N-terminal hotdog fold. Febs Lett., 598, 2024
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5MJT
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![BU of 5mjt by Molmil](/molmil-images/mine/5mjt) | Thrombin Mutant A190S in complex with (S) -1 - ((R) -2-amino-3,3-diphenylpropanoyl) -N- (3-chlorobenzyl) pyrrolidine-2-carboxamide | Descriptor: | DIMETHYL SULFOXIDE, GLYCEROL, Hirudin variant-2, ... | Authors: | Marca, A, Sandner, A, Heine, A, Klebe, G. | Deposit date: | 2016-12-01 | Release date: | 2017-12-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Thrombin Mutant A190S in complex with (S) -1 - ((R) -2-amino-3,3-diphenylpropanoyl) -N- (3-chlorobenzyl) pyrrolidine-2-carboxamide to be published
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8HPZ
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8HQ9
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8HQA
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8DCX
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![BU of 8dcx by Molmil](/molmil-images/mine/8dcx) | PI 3-kinase alpha with nanobody 3-159 | Descriptor: | Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Authors: | Hart, J.R, Liu, X, Pan, C, Liang, A, Ueno, L, Xu, Y, Quezada, A, Zou, X, Yang, S, Zhou, Q, Schoonooghe, S, Hassanzadeh-Ghassabeh, G, Xia, T, Shui, W, Yang, D, Vogt, P.K, Wang, M.-W. | Deposit date: | 2022-06-17 | Release date: | 2022-09-21 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Nanobodies and chemical cross-links advance the structural and functional analysis of PI3K alpha. Proc.Natl.Acad.Sci.USA, 119, 2022
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8PJE
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![BU of 8pje by Molmil](/molmil-images/mine/8pje) | Human Leukocyte Antigen class II allotype DR1 presenting influenza A virus haemagglutinin (HA)306-318 PKYVKQNTLKLAT | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... | Authors: | MacLachlan, B.J, Wall, A, Greenshields-Watson, A.L, Hesketh, S.J, Cole, D.K, Rizkallah, P.J, Godkin, A.J. | Deposit date: | 2023-06-23 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4 + T cell activation. Cell Rep, 43, 2024
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3IC7
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![BU of 3ic7 by Molmil](/molmil-images/mine/3ic7) | Crystal Structure of Putative Transcriptional Regulator of GntR Family from Bacteroides thetaiotaomicron | Descriptor: | Putative transcriptional regulator | Authors: | Kim, Y, Sather, A, Tesar, C, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-07-17 | Release date: | 2009-07-28 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.819 Å) | Cite: | Crystal Structure of Putative Transcriptional Regulator of GntR Family from Bacteroides thetaiotaomicron To be Published
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3ICA
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![BU of 3ica by Molmil](/molmil-images/mine/3ica) | The crystal structure of the beta subunit of a phenylalanyl-tRNA synthetase from Porphyromonas gingivalis W83 | Descriptor: | GLYCEROL, Phenylalanyl-tRNA synthetase beta chain, TRIS(HYDROXYETHYL)AMINOMETHANE | Authors: | Fan, Y, Sather, A, Keigher, L, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-07-17 | Release date: | 2009-07-28 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | The crystal structure of the beta subunit of a phenylalanyl-tRNA synthetase from Porphyromonas gingivalis W83 To be Published
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3IED
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![BU of 3ied by Molmil](/molmil-images/mine/3ied) | Crystal structure of N-terminal domain of Plasmodium falciparum Hsp90 (PF14_0417) in complex with AMPPN | Descriptor: | AMP PHOSPHORAMIDATE, Heat shock protein | Authors: | Pizarro, J.C, Wernimont, A.K, Lew, J, Hutchinson, A, Artz, J.D, Amaya, M.F, Plotnikova, O, Vedadi, M, Kozieradzki, I, Weigelt, J, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Botchkarev, A, Hui, R, Hills, T, Structural Genomics Consortium (SGC) | Deposit date: | 2009-07-22 | Release date: | 2009-08-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Crystal structure of N-terminal domain of Plasmodium falciparum Hsp90 (PF14_0417) in complex with AMPPN TO BE PUBLISHED
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5MRJ
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![BU of 5mrj by Molmil](/molmil-images/mine/5mrj) | Crystal structure of Endo-1,4-beta-xylanase-like protein from Acremonium chrysogenum | Descriptor: | Beta-xylanase, SULFATE ION | Authors: | Gabdulkhakov, A, Tishchenko, S, Lisov, A, Leontievsky, A. | Deposit date: | 2016-12-23 | Release date: | 2018-01-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of Endo-1,4-beta-xylanase-like protein from Acremonium chrysogenum To Be Published
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5MRS
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![BU of 5mrs by Molmil](/molmil-images/mine/5mrs) | Crystal structure of L1 protease Lysobacter sp. XL1 in complex with AEBSF | Descriptor: | 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Gabdulkhakov, A, Tishchenko, S, Lisov, A, Leontievsky, A. | Deposit date: | 2016-12-26 | Release date: | 2018-01-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of L1 protease Lysobacter sp. XL1 in complex with AEBSF To Be Published
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8PJF
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![BU of 8pjf by Molmil](/molmil-images/mine/8pjf) | Human Leukocyte Antigen class II allotype DR1 presenting P11T->R modified influenza A virus haemagglutinin (HA)306-318 PKYVKQNTLKLAR | Descriptor: | 1,2-ETHANEDIOL, HLA class II histocompatibility antigen, DR alpha chain, ... | Authors: | MacLachlan, B.J, Wall, A, Greenshields-Watson, A.L, Cole, D.K, Rizkallah, P.J, Godkin, A.J. | Deposit date: | 2023-06-23 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4 + T cell activation. Cell Rep, 43, 2024
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6M0T
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![BU of 6m0t by Molmil](/molmil-images/mine/6m0t) | Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum complexed with L-lysine and Cladosporin derivative (CL-2) | Descriptor: | (3R)-3-[(R)-[(2R,6S)-6-methyloxan-2-yl]-oxidanyl-methyl]-6,8-bis(oxidanyl)-3,4-dihydroisochromen-1-one, LYSINE, Lysine--tRNA ligase | Authors: | Babbar, P, Sharma, A, Manickam, Y. | Deposit date: | 2020-02-22 | Release date: | 2021-04-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Design, Synthesis, and Structural Analysis of Cladosporin-Based Inhibitors of Malaria Parasites. Acs Infect Dis., 7, 2021
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4XDG
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![BU of 4xdg by Molmil](/molmil-images/mine/4xdg) | Crystal Structure of Quinone Reductase II in complex with 2-(4-aminophenyl)-5-methoxy-1-oxy-indol-3-one molecule | Descriptor: | (2S)-2-(4-aminophenyl)-1-hydroxy-5-methoxy-1,2-dihydro-3H-indol-3-one, FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ... | Authors: | Sirigu, S, Nepveu, F, Vuillard, L, Ferry, G, Isabet, T, Thompson, A, Boutin, J.A. | Deposit date: | 2014-12-19 | Release date: | 2016-01-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Role of Quinone Reductase 2 in the Antimalarial Properties of Indolone-Type Derivatives. Molecules, 22, 2017
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3IG2
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![BU of 3ig2 by Molmil](/molmil-images/mine/3ig2) | The Crystal Structure of a Putative Phenylalanyl-tRNA synthetase (PheRS) beta chain domain from Bacteroides fragilis to 2.1A | Descriptor: | MAGNESIUM ION, Phenylalanyl-tRNA synthetase beta chain | Authors: | Stein, A.J, Sather, A, Hendricks, R, Keigher, L, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-07-27 | Release date: | 2009-09-01 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | The Crystal Structure of a Putative Phenylalanyl-tRNA synthetase (PheRS) beta chain domain from Bacteroides fragilis to 2.1A To be Published
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8PJG
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![BU of 8pjg by Molmil](/molmil-images/mine/8pjg) | F11 TCR in complex with Human Leukocyte Antigen class II allotype DR1 presenting P11T->R modified influenza A virus haemagglutinin (HA)306-318 PKYVKQNTLKLAR | Descriptor: | 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, HLA class II histocompatibility antigen, ... | Authors: | MacLachlan, B.J, Wall, A, Greenshields-Watson, A.L, Cole, D.K, Rizkallah, P.J, Godkin, A.J. | Deposit date: | 2023-06-23 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4 + T cell activation. Cell Rep, 43, 2024
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3IGR
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![BU of 3igr by Molmil](/molmil-images/mine/3igr) | The Crystal Structure of Ribosomal-protein-S5-alanine Acetyltransferase from Vibrio fischeri to 2.0A | Descriptor: | GLYCEROL, Ribosomal-protein-S5-alanine N-acetyltransferase, SODIUM ION | Authors: | Stein, A.J, Sather, A, Shackelford, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-07-28 | Release date: | 2009-09-01 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Crystal Structure of Ribosomal-protein-S5-alanine Acetyltransferase from Vibrio fischeri to 2.0A To be Published
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3IH5
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![BU of 3ih5 by Molmil](/molmil-images/mine/3ih5) | Crystal Structure of Electron Transfer Flavoprotein alpha-subunit from Bacteroides thetaiotaomicron | Descriptor: | Electron transfer flavoprotein alpha-subunit, FORMIC ACID, MALONIC ACID, ... | Authors: | Kim, Y, Sather, A, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-07-29 | Release date: | 2009-09-08 | Last modified: | 2015-04-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of Electron Transfer Flavoprotein alpha-subunit from Bacteroides thetaiotaomicron To be Published
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