7CB0
 
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7CB5
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7CB6
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8ZDB
 | | Cryo-EM structure of the human ubiquitylated 40S ribosome with RIOK3 | | Descriptor: | 18S rRNA, Serine/threonine-protein kinase RIO3, Small ribosomal subunit protein RACK1, ... | | Authors: | Huang, Z, Wang, M, Li, Y, Beckmann, R, Cheng, J. | | Deposit date: | 2024-05-01 | | Release date: | 2025-02-12 | | Last modified: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | RIOK3 mediates the degradation of 40S ribosomes.
Mol.Cell, 85, 2025
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8ZDD
 | | Cryo-EM structure of the human ubiquitylated pre-40S ribosome with RIOK3 (without NOB1) | | Descriptor: | 18S rRNA, Pre-rRNA-processing protein TSR1 homolog, Protein LTV1 homolog, ... | | Authors: | Huang, Z, Wang, M, Li, Y, Beckmann, R, Cheng, J. | | Deposit date: | 2024-05-01 | | Release date: | 2025-02-12 | | Last modified: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | RIOK3 mediates the degradation of 40S ribosomes.
Mol.Cell, 85, 2025
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3VTQ
 | | Novel HIV fusion inhibitor | | Descriptor: | Envelope glycoprotein gp160, fusion inhibitor MT-Sifuvirtide | | Authors: | Yao, X, Waltersperger, S, Wang, M, Cui, S. | | Deposit date: | 2012-06-02 | | Release date: | 2013-06-26 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.53 Å) | | Cite: | Crystal structure of a novel HIV fusion inhibitor
To be Published
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3UYI
 | | Crystal Structure of Perakine Reductase, Founder Member of a Novel AKR Subfamily with Unique Conformational Changes during NADPH Binding | | Descriptor: | Perakine reductase | | Authors: | Sun, L, Chen, Y, Rajendran, C, Panjikar, S, Mueller, U, Wang, M, Rosenthal, C, Mindnich, R, Penning, T.M, Stoeckigt, J. | | Deposit date: | 2011-12-06 | | Release date: | 2012-02-22 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.313 Å) | | Cite: | Crystal structure of perakine reductase, founding member of a novel aldo-keto reductase (AKR) subfamily that undergoes unique conformational changes during NADPH binding.
J.Biol.Chem., 287, 2012
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3V0T
 | | Crystal Structure of Perakine Reductase, Founder Member of a Novel AKR Subfamily with Unique Conformational Changes during NADPH Binding | | Descriptor: | 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, Perakine Reductase | | Authors: | Sun, L, Chen, Y, Rajendran, C, Panjikar, S, Mueller, U, Wang, M, Rosenthal, C, Mindnich, R, Penning, T.M, Stoeckigt, J. | | Deposit date: | 2011-12-08 | | Release date: | 2012-02-22 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.333 Å) | | Cite: | Crystal structure of perakine reductase, founding member of a novel aldo-keto reductase (AKR) subfamily that undergoes unique conformational changes during NADPH binding.
J.Biol.Chem., 287, 2012
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8ZDC
 | | Cryo-EM structure of the human ubiquitylated pre-40S ribosome with RIOK3 | | Descriptor: | 18S rRNA, Pre-rRNA-processing protein TSR1 homolog, Protein LTV1 homolog, ... | | Authors: | Huang, Z, Wang, M, Li, Y, Beckmann, R, Cheng, J. | | Deposit date: | 2024-05-01 | | Release date: | 2025-02-12 | | Last modified: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | RIOK3 mediates the degradation of 40S ribosomes.
Mol.Cell, 85, 2025
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8YOO
 | | Cryo-EM structure of the human 80S ribosome with 100 um Tigecycline | | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | Authors: | Li, X, Wang, M, Denk, T, Cheng, J. | | Deposit date: | 2024-03-13 | | Release date: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2 Å) | | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
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7YJP
 | | Crystal structure of MCR-1 treated by AuCl | | Descriptor: | GOLD ION, Probable phosphatidylethanolamine transferase Mcr-1 | | Authors: | Zhang, Q, Wang, M, Sun, H. | | Deposit date: | 2022-07-20 | | Release date: | 2023-02-01 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Gold drugs as colistin adjuvants in the fight against MCR-1 producing bacteria.
J.Biol.Inorg.Chem., 28, 2023
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7YJS
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7YJR
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7YJQ
 | | Crystal structure of MCR-1-S treated by auranofin | | Descriptor: | GOLD ION, Probable phosphatidylethanolamine transferase Mcr-1 | | Authors: | Zhang, Q, Sun, H, Wang, M. | | Deposit date: | 2022-07-20 | | Release date: | 2023-02-01 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Gold drugs as colistin adjuvants in the fight against MCR-1 producing bacteria.
J.Biol.Inorg.Chem., 28, 2023
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5MKK
 | | Crystal structure of the heterodimeric ABC transporter TmrAB, a homolog of the antigen translocation complex TAP | | Descriptor: | Multidrug resistance ABC transporter ATP-binding and permease protein, SULFATE ION | | Authors: | Noell, A, Thomas, C, Tomasiak, T.M, Olieric, V, Wang, M, Diederichs, K, Stroud, R.M, Pos, K.M, Tampe, R. | | Deposit date: | 2016-12-05 | | Release date: | 2017-01-18 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structure and mechanistic basis of a functional homolog of the antigen transporter TAP.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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7XT3
 | | Crystal Structure of Hepatitis virus A 2C protein 128-335 aa | | Descriptor: | Genome polyprotein, PHOSPHATE ION | | Authors: | Chen, P, Wojdyla, J.A, Li, Z, Wang, M, Cui, S. | | Deposit date: | 2022-05-16 | | Release date: | 2022-07-27 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Biochemical and structural characterization of hepatitis A virus 2C reveals an unusual ribonuclease activity on single-stranded RNA.
Nucleic Acids Res., 50, 2022
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5Y6K
 | | Human serum trnasferrin bound to a fluorescent probe | | Descriptor: | (2S)-6-[2-(7-azido-4-methyl-2-oxidanylidene-chromen-3-yl)ethanoylamino]-2-[bis(2-hydroxy-2-oxoethyl)amino]hexanoic acid, FE (III) ION, MALONATE ION, ... | | Authors: | Jiang, N, Cheng, T, Wang, M, Chan, G.C.F, Jin, L, Li, H, Sun, H. | | Deposit date: | 2017-08-12 | | Release date: | 2018-01-24 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.86 Å) | | Cite: | Tracking iron-associated proteomes in pathogens by a fluorescence approach.
Metallomics, 10, 2018
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5ZBA
 | | Crystal structure of Rtt109-Asf1-H3-H4-CoA complex | | Descriptor: | COENZYME A, DNA damage response protein Rtt109, putative, ... | | Authors: | Zhang, L, Serra-Cardona, A, Zhou, H, Wang, M, Yang, N, Zhang, Z, Xu, R.M. | | Deposit date: | 2018-02-10 | | Release date: | 2018-07-25 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Multisite Substrate Recognition in Asf1-Dependent Acetylation of Histone H3 K56 by Rtt109.
Cell, 174, 2018
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5ZB9
 | | Crystal structure of Rtt109 from Aspergillus fumigatus | | Descriptor: | DNA damage response protein Rtt109, putative, GLYCEROL | | Authors: | Zhang, L, Serra-Cardona, A, Zhou, H, Wang, M, Yang, N, Zhang, Z, Xu, R.M. | | Deposit date: | 2018-02-10 | | Release date: | 2018-07-25 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.502 Å) | | Cite: | Multisite Substrate Recognition in Asf1-Dependent Acetylation of Histone H3 K56 by Rtt109.
Cell, 174, 2018
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5ZBB
 | | Crystal structure of Rtt109-Asf1-H3-H4 complex | | Descriptor: | DI(HYDROXYETHYL)ETHER, DNA damage response protein Rtt109, putative, ... | | Authors: | Zhang, L, Serra-Cardona, A, Zhou, H, Wang, M, Yang, N, Zhang, Z, Xu, R.M. | | Deposit date: | 2018-02-10 | | Release date: | 2018-07-25 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Multisite Substrate Recognition in Asf1-Dependent Acetylation of Histone H3 K56 by Rtt109.
Cell, 174, 2018
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5ZO2
 | | Crystal structure of mouse nectin-like molecule 4 (mNecl-4) full ectodomain in complex with mouse nectin-like molecule 1 (mNecl-1) Ig1 domain, 3.3A | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Cell adhesion molecule 3, Cell adhesion molecule 4 | | Authors: | Liu, X, An, T, Li, D, Fan, Z, Xiang, P, Li, C, Ju, W, Li, J, Hu, G, Qin, B, Yin, B, Wojdyla, J.A, Wang, M, Yuan, J, Qiang, B, Shu, P, Cui, S, Peng, X. | | Deposit date: | 2018-04-12 | | Release date: | 2019-01-30 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (3.29 Å) | | Cite: | Structure of the heterophilic interaction between the nectin-like 4 and nectin-like 1 molecules.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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8K2B
 | | Cryo-EM structure of the human 39S mitoribosome with Tigecycline | | Descriptor: | 16s rRNA, 39S ribosomal protein L22, mitochondrial, ... | | Authors: | Li, X, Wang, M, Cheng, J. | | Deposit date: | 2023-07-12 | | Release date: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
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8K2A
 | | Cryo-EM structure of the human 55S mitoribosome with Tigecycline | | Descriptor: | 12S rRNA, 16S rRNA, 39S ribosomal protein L22, ... | | Authors: | Li, X, Wang, M, Cheng, J. | | Deposit date: | 2023-07-12 | | Release date: | 2024-07-10 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
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7BET
 | | Structure of Ribonucleotide reductase R2 from Escherichia coli collected by femtosecond serial crystallography on a COC membrane | | Descriptor: | FE (III) ION, Ribonucleoside-diphosphate reductase 1 subunit beta | | Authors: | Aurelius, O, John, J, Martiel, I, Marsh, M, Vera, L, Huang, C.Y, Olieric, V, Leonarski, P, Nass, K, Padeste, C, Karpik, A, Hogbom, M, Wang, M, Pedrini, B. | | Deposit date: | 2020-12-24 | | Release date: | 2022-01-12 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Commissioning results from the SwissMX instrument for fixed target macromolecular crystallography at SwissFEL
To Be Published
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5ZO1
 | | Crystal structure of mouse nectin-like molecule 4 (mNecl-4) full ectodomain (Ig1-Ig3), 2.2A | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Cell adhesion molecule 4, GLYCEROL | | Authors: | Liu, X, An, T, Li, D, Fan, Z, Xiang, P, Li, C, Ju, W, Li, J, Hu, G, Qin, B, Yin, B, Wojdyla, J.A, Wang, M, Yuan, J, Qiang, B, Shu, P, Cui, S, Peng, X. | | Deposit date: | 2018-04-12 | | Release date: | 2019-01-30 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.201 Å) | | Cite: | Structure of the heterophilic interaction between the nectin-like 4 and nectin-like 1 molecules.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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