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5XFR
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BU of 5xfr by Molmil
Ternary complex of MTF2, DNA and histone
Descriptor: DNA (5'-D(*GP*GP*GP*CP*GP*GP*CP*CP*GP*CP*CP*CP*T)-3'), Metal-response element-binding transcription factor 2, Peptide from Histone H3.1, ...
Authors:Wang, Z, Li, H.
Deposit date:2017-04-11
Release date:2017-09-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Polycomb-like proteins link the PRC2 complex to CpG islands
Nature, 549, 2017
5XFP
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BU of 5xfp by Molmil
Binary complex of PHF1 and a double stranded DNA
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (5'-D(*GP*GP*GP*CP*GP*GP*CP*CP*GP*CP*CP*CP*T)-3'), PHD finger protein 1, ...
Authors:Wang, Z, Li, H.
Deposit date:2017-04-11
Release date:2017-09-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Polycomb-like proteins link the PRC2 complex to CpG islands
Nature, 549, 2017
5XOW
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BU of 5xow by Molmil
Crystal structure of T. thermophilus Argonaute protein complexed with a bulge 6'A7' on the target strand
Descriptor: DNA (5'-D(P*(TD)P*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3'), MAGNESIUM ION, RNA (5'-R(P*UP*AP*CP*AP*AP*CP*CP*UP*AP*CP*UP*AP*AP*CP*CP*UP*CP*G)-3'), ...
Authors:Sheng, G, Wang, J, Zhao, H, Wang, Y.
Deposit date:2017-05-31
Release date:2017-10-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.902 Å)
Cite:Structure/cleavage-based insights into helical perturbations at bulge sites within T. thermophilus Argonaute silencing complexes
Nucleic Acids Res., 45, 2017
5XFQ
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BU of 5xfq by Molmil
Ternary complex of PHF1, a DNA duplex and a histone peptide
Descriptor: DNA (5'-D(*GP*GP*GP*CP*GP*GP*CP*CP*GP*CP*CP*CP*T)-3'), PHD finger protein 1, Peptide from Histone H3, ...
Authors:Wang, Z, Li, H.
Deposit date:2017-04-11
Release date:2017-09-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Polycomb-like proteins link the PRC2 complex to CpG islands
Nature, 549, 2017
5XFO
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BU of 5xfo by Molmil
Structure of the N-terminal domains of PHF1
Descriptor: PHD finger protein 1, ZINC ION
Authors:Wang, Z, Li, H.
Deposit date:2017-04-11
Release date:2017-09-13
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Polycomb-like proteins link the PRC2 complex to CpG islands
Nature, 549, 2017
5XOU
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BU of 5xou by Molmil
Crystal structure of T. thermophilus Argonaute protein complexed with a bulge 7T8 on the guide strand
Descriptor: DNA (5'-D(*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3'), DNA (5'-D(P*TP*GP*AP*GP*GP*TP*AP*TP*GP*GP*TP*TP*GP*T)-3'), MAGNESIUM ION, ...
Authors:Sheng, G, Wang, J, Zhao, H, Wang, Y.
Deposit date:2017-05-31
Release date:2017-10-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Structure/cleavage-based insights into helical perturbations at bulge sites within T. thermophilus Argonaute silencing complexes
Nucleic Acids Res., 45, 2017
5Y87
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BU of 5y87 by Molmil
Structure-based Insights into Self-Cleavage by a Four-way Junctional Twister-Sister Ribozyme
Descriptor: DNA/RNA (50-MER), MANGANESE (II) ION, RNA (5'-R(P*AP*CP*CP*CP*GP*CP*AP*AP*GP*GP*CP*CP*GP*AP*CP*GP*GP*C)-3')
Authors:Zheng, L, Micura, R.L, Ren, A.
Deposit date:2017-08-19
Release date:2017-11-22
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.132 Å)
Cite:Structure-based insights into self-cleavage by a four-way junctional twister-sister ribozyme
Nat Commun, 8, 2017
5Y85
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BU of 5y85 by Molmil
Structure-based Insights into Self-Cleavage by a Four-way Junctional Twister-Sister Ribozyme
Descriptor: DNA/RNA (50-MER), MAGNESIUM ION, RNA (5'-R(P*AP*CP*CP*CP*GP*CP*AP*AP*GP*GP*CP*CP*GP*AP*CP*GP*GP*C)-3')
Authors:Zheng, L, Micura, R.L, Ren, A.
Deposit date:2017-08-18
Release date:2017-11-22
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Structure-based insights into self-cleavage by a four-way junctional twister-sister ribozyme
Nat Commun, 8, 2017
6DBP
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BU of 6dbp by Molmil
RNA-recognition motif 1 of human MSI2
Descriptor: RNA-binding protein Musashi homolog 2
Authors:Goldgur, Y, Kharas, M.G, Minuesa, G.
Deposit date:2018-05-03
Release date:2019-05-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.603 Å)
Cite:Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia.
Nat Commun, 10, 2019
5DDO
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BU of 5ddo by Molmil
Structural and Dynamic Basis for Low Affinity-High Selectivity Binding of L-glutamine by the Gln-riboswitch
Descriptor: L-glutamine riboswitch (58-MER), U1 small nuclear ribonucleoprotein A
Authors:Ren, A, Patel, D.
Deposit date:2015-08-25
Release date:2015-12-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch.
Cell Rep, 13, 2015
1SI2
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BU of 1si2 by Molmil
Crystal structure of the PAZ domain of human eIF2c1 in complex with a 9-mer siRNA-like duplex of deoxynucleotide overhang
Descriptor: 5'-R(*CP*GP*UP*GP*AP*CP*U)-D(P*CP*T)-3', Eukaryotic translation initiation factor 2C 1
Authors:Ye, K, Ma, J.B, Patel, D.
Deposit date:2004-02-26
Release date:2004-05-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain.
Nature, 429, 2004
1SI3
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BU of 1si3 by Molmil
Crystal structure of the PAZ domain of human eIF2c1 in complex with a 9-mer siRNA-like duplex
Descriptor: 5'-R(*CP*GP*UP*GP*AP*CP*UP*CP*U)-3', Eukaryotic translation initiation factor 2C 1
Authors:Ye, K, Ma, J.B, Patel, D.
Deposit date:2004-02-27
Release date:2004-05-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain.
Nature, 429, 2004
6JQ5
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BU of 6jq5 by Molmil
The structure of Hatchet Ribozyme
Descriptor: MAGNESIUM ION, RNA (82-MER)
Authors:Ren, A, Zheng, L.
Deposit date:2019-03-29
Release date:2019-06-12
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.059 Å)
Cite:Hatchet ribozyme structure and implications for cleavage mechanism.
Proc.Natl.Acad.Sci.USA, 116, 2019
6JQ6
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BU of 6jq6 by Molmil
Hatchet Ribozyme Structure soaking with Ir(NH3)6+
Descriptor: IRIDIUM HEXAMMINE ION, RNA (81-MER)
Authors:Ren, A, Zheng, L.
Deposit date:2019-03-29
Release date:2019-06-12
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.626 Å)
Cite:Hatchet ribozyme structure and implications for cleavage mechanism.
Proc.Natl.Acad.Sci.USA, 116, 2019
5HH7
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BU of 5hh7 by Molmil
crystal structure of Arabidopsis ORC1b BAH-PHD cassette in complex with unmodified H3 peptide
Descriptor: Histone H3 1-15 peptide, Origin of replication complex subunit 1B, ZINC ION
Authors:Li, S, Du, J.
Deposit date:2016-01-10
Release date:2016-03-09
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Structural Basis for the Unique Multivalent Readout of Unmodified H3 Tail by Arabidopsis ORC1b BAH-PHD Cassette
Structure, 24, 2016
6MUS
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BU of 6mus by Molmil
Cryo-EM structure of larger Csm-crRNA-target RNA ternary complex in type III-A CRISPR-Cas system
Descriptor: RNA (25-MER), RNA (33-MER), Uncharacterized protein Csm1, ...
Authors:Jia, N, Wang, C, Eng, E.T.
Deposit date:2018-10-23
Release date:2018-12-12
Last modified:2019-01-30
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity.
Mol. Cell, 73, 2019
3QL9
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BU of 3ql9 by Molmil
Monoclinic complex structure of ATRX ADD bound to histone H3K9me3 peptide
Descriptor: Transcriptional regulator ATRX, ZINC ION, peptide of Histone H3.3
Authors:Xiang, B, Li, H.
Deposit date:2011-02-02
Release date:2011-06-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (0.93 Å)
Cite:ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome
Nat.Struct.Mol.Biol., 18, 2011
3QLA
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BU of 3qla by Molmil
Hexagonal complex structure of ATRX ADD bound to H3K9me3 peptide
Descriptor: POTASSIUM ION, Transcriptional regulator ATRX, ZINC ION, ...
Authors:Xiang, B, Li, H.
Deposit date:2011-02-02
Release date:2011-06-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome
Nat.Struct.Mol.Biol., 18, 2011
7LMM
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BU of 7lmm by Molmil
Crystal structure of bovine DNMT1 BAH1 domain in complex with H4K20me2
Descriptor: DNA (cytosine-5)-methyltransferase 1,DNA (cytosine-5)-methyltransferase 1, Histone H4, ZINC ION
Authors:Ren, W, Song, J.
Deposit date:2021-02-05
Release date:2021-02-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.798 Å)
Cite:DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation.
Nat Commun, 12, 2021
7LMK
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BU of 7lmk by Molmil
Crystal structure of bovine DNMT1 BAH1 domain in complex with H4K20me3
Descriptor: DNA (cytosine-5)-methyltransferase 1, Histone H4, ZINC ION
Authors:Ren, W, Song, J.
Deposit date:2021-02-05
Release date:2021-02-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.647 Å)
Cite:DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation.
Nat Commun, 12, 2021
2KU7
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BU of 2ku7 by Molmil
Solution structure of MLL1 PHD3-Cyp33 RRM chimeric protein
Descriptor: MLL1 PHD3-Cyp33 RRM chimeric protein
Authors:Song, J, Wang, Z, Patel, D.
Deposit date:2010-02-12
Release date:2010-07-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression.
Cell(Cambridge,Mass.), 141, 2010
2LA5
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BU of 2la5 by Molmil
RNA Duplex-Quadruplex Junction Complex with FMRP RGG peptide
Descriptor: Fragile X mental retardation 1 protein, RNA (36-MER)
Authors:Phan, A, Kuryavyi, V, Darnell, J, Serganov, A, Majumdar, A, Ilin, S, Darnell, R, Patel, D.
Deposit date:2011-03-03
Release date:2011-06-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction.
Nat.Struct.Mol.Biol., 18, 2011
7DUF
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BU of 7duf by Molmil
Crystal structure of VIM1 PHD finger.
Descriptor: E3 ubiquitin-protein ligase ORTHRUS 2, ZINC ION
Authors:Abhishek, S, Deeksha, W, Patel, D.J, Rajakumara, E.
Deposit date:2021-01-08
Release date:2021-08-25
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Helical and beta-Turn Conformations in the Peptide Recognition Regions of the VIM1 PHD Finger Abrogate H3K4 Peptide Recognition.
Biochemistry, 60, 2021
2XUE
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BU of 2xue by Molmil
CRYSTAL STRUCTURE OF JMJD3
Descriptor: 2-OXOGLUTARIC ACID, FE (III) ION, LYSINE-SPECIFIC DEMETHYLASE 6B, ...
Authors:Chung, C, Rowland, P, Mosley, J, Thomas, P.J.
Deposit date:2010-10-19
Release date:2011-12-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Selective Jumonji H3K27 Demethylase Inhibitor Modulates the Proinflammatory Macrophage Response
Nature, 488, 2012
6PZV
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BU of 6pzv by Molmil
Crystal Structure of Bovine DNMT1 RFTS domain in complex with H3K9me3 and Ubiquitin
Descriptor: CITRATE ANION, DNA (cytosine-5)-methyltransferase 1, Histone H3.3, ...
Authors:Ren, W, Song, J.
Deposit date:2019-08-01
Release date:2020-07-15
Last modified:2020-08-12
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation.
Proc.Natl.Acad.Sci.USA, 117, 2020

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