6TPL
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![BU of 6tpl by Molmil](/molmil-images/mine/6tpl) | D0-D1 domain of Intimin | Descriptor: | CHLORIDE ION, Intimin, MAGNESIUM ION | Authors: | Weikum, J, Leo, J.C, Morth, J.P. | Deposit date: | 2019-12-13 | Release date: | 2021-01-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The extracellular juncture domains in the intimin passenger adopt a constitutively extended conformation inducing restraints to its sphere of action. Sci Rep, 10, 2020
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6TH1
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![BU of 6th1 by Molmil](/molmil-images/mine/6th1) | IE1 from rat cytomegalovirus | Descriptor: | Immediate early protein 1 | Authors: | Schweininger, J, Muller, Y.A. | Deposit date: | 2019-11-18 | Release date: | 2020-11-25 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Cytomegalovirus immediate-early 1 proteins form a structurally distinct protein class with adaptations determining cross-species barriers. Plos Pathog., 17, 2021
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1BQJ
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![BU of 1bqj by Molmil](/molmil-images/mine/1bqj) | CRYSTAL STRUCTURE OF D(ACCCT) | Descriptor: | DNA (5'-D(*AP*CP*CP*CP*T)-3') | Authors: | Weil, J, Min, T, Yang, C, Wang, S, Sutherland, C, Sinha, N, Kang, C.H. | Deposit date: | 1998-08-17 | Release date: | 1999-03-18 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Stabilization of the i-motif by intramolecular adenine-adenine-thymine base triple in the structure of d(ACCCT). Acta Crystallogr.,Sect.D, 55, 1999
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1CN0
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![BU of 1cn0 by Molmil](/molmil-images/mine/1cn0) | CRYSTAL STRUCTURE OF D(ACCCT) | Descriptor: | DNA (5'-D(*AP*CP*CP*CP*T)-3') | Authors: | Weil, J, Min, T, Cheng, Y, Wang, S, Sutherland, C, Sinha, N, Kang, C. | Deposit date: | 1999-05-24 | Release date: | 2000-05-24 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Stabilization of the i-motif by intramolecular adenine-adenine-thymine base triple in the structure of d(ACCCT). Acta Crystallogr.,Sect.D, 55, 1999
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1JWE
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![BU of 1jwe by Molmil](/molmil-images/mine/1jwe) | NMR Structure of the N-Terminal Domain of E. Coli Dnab Helicase | Descriptor: | PROTEIN (DNAB HELICASE) | Authors: | Weigelt, J, Brown, S.E, Miles, C.S, Dixon, N.E, Otting, G. | Deposit date: | 1999-01-22 | Release date: | 1999-01-27 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | NMR structure of the N-terminal domain of E. coli DnaB helicase: implications for structure rearrangements in the helicase hexamer. Structure Fold.Des., 7, 1999
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1E17
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![BU of 1e17 by Molmil](/molmil-images/mine/1e17) | Solution structure of the DNA binding domain of the human Forkhead transcription factor AFX (FOXO4) | Descriptor: | AFX | Authors: | Weigelt, J, Climent, I, Dahlman-Wright, K, Wikstrom, M. | Deposit date: | 2000-04-25 | Release date: | 2000-08-18 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | 1H, 13C and 15N Resonance Assignments of the DNA Binding Domain of the Human Forkhead Transcription Factor Afx J.Biomol.NMR, 17, 2000
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8PXV
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![BU of 8pxv by Molmil](/molmil-images/mine/8pxv) | Targeting extended blood antigens by Akkermansia muciniphila enzymes unveils a missing link for generating universal donor blood | Descriptor: | Beta-N-acetylhexosaminidase, GLYCEROL, SODIUM ION, ... | Authors: | Weikum, J, Jensen, M, Abou Hachem, M, Morth, J.P. | Deposit date: | 2023-07-24 | Release date: | 2024-02-28 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Akkermansia muciniphila exoglycosidases target extended blood group antigens to generate ABO-universal blood. Nat Microbiol, 9, 2024
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6HHF
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![BU of 6hhf by Molmil](/molmil-images/mine/6hhf) | Crystal Structure of AKT1 in Complex with Covalent-Allosteric AKT Inhibitor Borussertib | Descriptor: | Borussertib, RAC-alpha serine/threonine-protein kinase | Authors: | Landel, I, Weisner, J, Mueller, M.P, Scheinpflug, R, Rauh, D. | Deposit date: | 2018-08-28 | Release date: | 2019-03-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Preclinical Efficacy of Covalent-Allosteric AKT Inhibitor Borussertib in Combination with Trametinib inKRAS-Mutant Pancreatic and Colorectal Cancer. Cancer Res., 79, 2019
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5HWL
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![BU of 5hwl by Molmil](/molmil-images/mine/5hwl) | Human glutathione s-transferase Mu2 complexed with BDEA, monoclinic crystal form | Descriptor: | GLUTATHIONE, Glutathione S-transferase Mu 2, N,N'-(butane-1,4-diyl)bis{2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetamide} | Authors: | Zhang, X, Wei, J, Wu, S, Zhang, H.P, Luo, M, Yang, X.L, Liao, F, Wang, D.Q. | Deposit date: | 2016-01-29 | Release date: | 2017-11-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Human glutathione s-transferase Mu2 complexed with BDEA, monoclinic crystal form To Be Published
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5IHW
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![BU of 5ihw by Molmil](/molmil-images/mine/5ihw) | The crystal structure of SdrE from staphylococcus aureus | Descriptor: | Serine-aspartate repeat-containing protein E | Authors: | Zhang, S, Wei, J, Wu, S, Zhang, X, Luo, M, Wang, D. | Deposit date: | 2016-02-29 | Release date: | 2017-03-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | The crystal structure of SdrE from staphylococcus aureus To Be Published
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8E3I
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![BU of 8e3i by Molmil](/molmil-images/mine/8e3i) | CRYO-EM STRUCTURE OF the human MPSF IN COMPLEX WITH THE AUUAAA poly(A) signal | Descriptor: | Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, RNA (5'-R(P*CP*AP*UP*UP*AP*AP*AP*CP*AP*AP*C)-3'), ... | Authors: | Gutierrez, P.A, Wei, J, Sun, Y, Tong, L. | Deposit date: | 2022-08-17 | Release date: | 2023-01-18 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.53 Å) | Cite: | Molecular basis for the recognition of the AUUAAA polyadenylation signal by mPSF. Rna, 28, 2022
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8E3Q
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![BU of 8e3q by Molmil](/molmil-images/mine/8e3q) | CRYO-EM STRUCTURE OF the human MPSF | Descriptor: | Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, ZINC ION, ... | Authors: | Gutierrez, P.A, Wei, J, Sun, Y, Tong, L. | Deposit date: | 2022-08-17 | Release date: | 2023-01-18 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.68 Å) | Cite: | Molecular basis for the recognition of the AUUAAA polyadenylation signal by mPSF. Rna, 28, 2022
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4FYP
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![BU of 4fyp by Molmil](/molmil-images/mine/4fyp) | Crystal Structure of Plant Vegetative Storage Protein | Descriptor: | MAGNESIUM ION, Vegetative storage protein 1 | Authors: | Chen, Y, Wei, J, Wang, M, Gong, W, Zhang, M. | Deposit date: | 2012-07-05 | Release date: | 2013-06-26 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The crystal structure of Arabidopsis VSP1 reveals the plant class C-like phosphatase structure of the DDDD superfamily of phosphohydrolases Plos One, 7, 2012
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4HCC
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![BU of 4hcc by Molmil](/molmil-images/mine/4hcc) | The zinc ion bound form of crystal structure of E.coli ExoI-ssDNA complex | Descriptor: | DNA (5'-D(*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), Exodeoxyribonuclease I, ISOPROPYL ALCOHOL, ... | Authors: | Qiu, R, Wei, J, Lou, T, Liu, M, Ji, C, Gong, W. | Deposit date: | 2012-09-29 | Release date: | 2013-10-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.96 Å) | Cite: | The structures of Escherichia coli exonuclease I in complex with the single strand DNA To be published
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4HCB
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![BU of 4hcb by Molmil](/molmil-images/mine/4hcb) | The metal-free form of crystal structure of E.coli ExoI-ssDNA complex | Descriptor: | DNA (5'-D(*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), Exodeoxyribonuclease I, GLYCEROL, ... | Authors: | Qiu, R, Wei, J, Lou, T, Liu, M, Ji, C, Gong, W. | Deposit date: | 2012-09-29 | Release date: | 2013-10-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The structures of Escherichia coli exonuclease I in complex with the single strand DNA To be published
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5T5H
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![BU of 5t5h by Molmil](/molmil-images/mine/5t5h) | Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit | Descriptor: | 40S ribosomal protein L14, 5.8S rRNA, 5S rRNA, ... | Authors: | Liu, Z, Gutierrez-Vargas, C, Wei, J, Grassucci, R.A, Ramesh, M, Espina, N, Sun, M, Tutuncuoglu, B, Madison-Antenucci, S, Woolford Jr, J.L, Tong, L, Frank, J. | Deposit date: | 2016-08-31 | Release date: | 2016-10-12 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (2.54 Å) | Cite: | Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit. Proc.Natl.Acad.Sci.USA, 113, 2016
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3CPS
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![BU of 3cps by Molmil](/molmil-images/mine/3cps) | Crystal structure of Cryptosporidium parvum glyceraldehyde-3-phosphate dehydrogenase | Descriptor: | Glyceraldehyde 3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Wernimont, A.K, Lew, J, Kozieradzki, I, Cossar, D, Schapiro, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Pizarro, J, Hills, T, Structural Genomics Consortium (SGC) | Deposit date: | 2008-04-01 | Release date: | 2008-04-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of Cryptosporidium parvum glyceraldehyde-3-phosphate dehydrogenase. To be Published
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3COU
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![BU of 3cou by Molmil](/molmil-images/mine/3cou) | Crystal structure of human Nudix motif 16 (NUDT16) | Descriptor: | Nucleoside diphosphate-linked moiety X motif 16 | Authors: | Tresaugues, L, Moche, M, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Herman, M.D, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Lehtio, L, Nilsson, M.E, Nyman, T, Persson, C, Sagemark, J, Schueler, H, Svensson, L, Thorsell, A.G, Van Den Berg, S, Welin, M, Weigelt, J, Wikstrom, M, Nordlund, P, Structural Genomics Consortium (SGC) | Deposit date: | 2008-03-29 | Release date: | 2008-04-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of human Nudix motif 16 (NUDT16). To be Published
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3CLV
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![BU of 3clv by Molmil](/molmil-images/mine/3clv) | Crystal Structure of Rab5a from plasmodium falciparum, PFB0500c | Descriptor: | CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, Rab5 protein, ... | Authors: | Chattopadhyay, D, Wernimont, A.K, Langsley, G, Lew, J, Kozieradzki, I, Cossar, D, Schapira, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Sukumar, D, Structural Genomics Consortium (SGC) | Deposit date: | 2008-03-20 | Release date: | 2008-07-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Crystal Structure of Rab5a from plasmodium falciparum, PFB0500c To be Published
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3MDZ
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![BU of 3mdz by Molmil](/molmil-images/mine/3mdz) | Crystal Structure of Human Carbonic Anhydrase VII [isoform 1], CA7 | Descriptor: | 6-ethoxy-1,3-benzothiazole-2-sulfonamide, Carbonic anhydrase 7, GLYCEROL, ... | Authors: | Ugochukwu, E, Shafqat, N, Pilka, E, Chaikuad, A, Krojer, T, Muniz, J, Kim, J, Bray, J, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, von Delft, F, Carpenter, E.P, Yue, W.W, Oppermann, U, Structural Genomics Consortium (SGC) | Deposit date: | 2010-03-31 | Release date: | 2010-06-23 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Crystal Structure of Human Carbonic Anhydrase VII [isoform 1], CA7 to be published
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3D3L
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![BU of 3d3l by Molmil](/molmil-images/mine/3d3l) | The 2.6 A crystal structure of the lipoxygenase domain of human arachidonate 12-lipoxygenase, 12S-type | Descriptor: | Arachidonate 12-lipoxygenase, 12S-type, FE (III) ION | Authors: | Tresaugues, L, Moche, M, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Herman, M.D, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Lehtio, L, Nilsson, M.E, Nyman, T, Olesen, K, Persson, C, Sagemark, J, Schueler, H, Svensson, L, Thorsell, A.G, Van Den Berg, S, Welin, M, Weigelt, J, Wikstrom, M, Nordlund, P, Structural Genomics Consortium (SGC) | Deposit date: | 2008-05-12 | Release date: | 2008-09-09 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of the lipoxygenase domain of human Arachidonate 12-lipoxygenase, 12S-type. To be Published
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2RF0
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![BU of 2rf0 by Molmil](/molmil-images/mine/2rf0) | Crystal structure of human mixed lineage kinase MAP3K10 SH3 domain | Descriptor: | 1,2-ETHANEDIOL, Mitogen-activated protein kinase kinase kinase 10 | Authors: | Ugochukwu, E, Eswaran, J, Elkins, J, Keates, T, Pike, A.C.W, Berridge, G, Savitsky, P, Sundstrom, M, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, von Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2007-09-27 | Release date: | 2007-10-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The crystal structure of human Mixed lineage kinase MAP3K10 SH3 domain. To be Published
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2R77
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![BU of 2r77 by Molmil](/molmil-images/mine/2r77) | Crystal structure of phosphatidylethanolamine-binding protein, pfl0955c, from Plasmodium falciparum | Descriptor: | Phosphatidylethanolamine-binding protein, putative | Authors: | Wernimont, A.K, Lew, J, Kozieradzki, I, Lin, Y.H, Sun, X, Khuu, C, Crombette, L, Zhao, Y, Schapira, M, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Artz, J.D, Xiao, T, Structural Genomics Consortium (SGC) | Deposit date: | 2007-09-07 | Release date: | 2007-09-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structure of phosphatidylethanolamine-binding protein, pfl0955c, from Plasmodium falciparum. To be Published
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2REY
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![BU of 2rey by Molmil](/molmil-images/mine/2rey) | Crystal structure of the PDZ domain of human dishevelled 2 (homologous to Drosophila dsh) | Descriptor: | Segment polarity protein dishevelled homolog DVL-2 | Authors: | Papagrigoriou, E, Gileadi, C, Elkins, J, Cooper, C, Ugochukwu, E, Turnbull, A, Pike, A.C.W, Gileadi, O, von Delft, F, Sundstrom, M, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Doyle, D, Structural Genomics Consortium (SGC) | Deposit date: | 2007-09-27 | Release date: | 2007-10-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal structure of the PDZ domains of human dishevelled 2 (homologous to Drosophila dsh). To be Published
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2RCY
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![BU of 2rcy by Molmil](/molmil-images/mine/2rcy) | Crystal structure of Plasmodium falciparum pyrroline carboxylate reductase (MAL13P1.284) with NADP bound | Descriptor: | GLYCEROL, MAGNESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Wernimont, A.K, Lew, J, Lin, Y.H, Ren, H, Sun, X, Khuu, C, Hassanali, A, Wasney, G, Zhao, Y, Kozieradzki, I, Schapira, M, Bochkarev, A, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Hui, R, Artz, J.D, Amani, M, Structural Genomics Consortium (SGC) | Deposit date: | 2007-09-20 | Release date: | 2007-10-23 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of Plasmodium falciparum pyrroline carboxylate reductase (MAL13P1.284) with NADP bound. To be Published
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