5T5N
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![BU of 5t5n by Molmil](/molmil-images/mine/5t5n) | Calcium-activated chloride channel bestrophin-1 (BEST1), triple mutant: I76A, F80A, F84A; in complex with an Fab antibody fragment, chloride, and calcium | Descriptor: | CALCIUM ION, CHLORIDE ION, Fab antibody fragment, ... | Authors: | Long, S.B, Vaisey, G. | Deposit date: | 2016-08-31 | Release date: | 2016-11-30 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Distinct regions that control ion selectivity and calcium-dependent activation in the bestrophin ion channel. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5V7P
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![BU of 5v7p by Molmil](/molmil-images/mine/5v7p) | Atomic structure of the eukaryotic intramembrane Ras methyltransferase ICMT (isoprenylcysteine carboxyl methyltransferase), in complex with a monobody | Descriptor: | DECANE, Protein-S-isoprenylcysteine O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Long, S.B, Diver, M.M, Pedi, L, Koide, A, Koide, S. | Deposit date: | 2017-03-20 | Release date: | 2018-01-17 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Atomic structure of the eukaryotic intramembrane RAS methyltransferase ICMT. Nature, 553, 2018
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5VG9
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![BU of 5vg9 by Molmil](/molmil-images/mine/5vg9) | Structure of the eukaryotic intramembrane Ras methyltransferase ICMT (isoprenylcysteine carboxyl methyltransferase) without a monobody | Descriptor: | Protein-S-isoprenylcysteine O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Long, S.B, Diver, M.M, Pedi, L, Koide, A, Koide, S. | Deposit date: | 2017-04-10 | Release date: | 2018-01-17 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Atomic structure of the eukaryotic intramembrane RAS methyltransferase ICMT. Nature, 553, 2018
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6BBG
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6BBI
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6BBH
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6BBF
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1S64
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![BU of 1s64 by Molmil](/molmil-images/mine/1s64) | Rat protein geranylgeranyltransferase type-I complexed with L-778,123 and a sulfate anion | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-[(5-{[4-(3-CHLOROPHENYL)-3-OXOPIPERAZIN-1-YL]METHYL}-1H-IMIDAZOL-1-YL)METHYL]BENZONITRILE, CHLORIDE ION, ... | Authors: | Reid, T.S, Long, S.B, Beese, L.S. | Deposit date: | 2004-01-22 | Release date: | 2004-07-27 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Crystallographic Analysis Reveals that Anticancer Clinical Candidate L-778,123 Inhibits Protein Farnesyltransferase and Geranylgeranyltransferase-I by Different Binding Modes. Biochemistry, 43, 2004
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6N27
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![BU of 6n27 by Molmil](/molmil-images/mine/6n27) | BEST1 calcium-bound closed state | Descriptor: | Bestrophin homolog, CALCIUM ION | Authors: | Miller, A.N, Vaisey, G, Long, S.B. | Deposit date: | 2018-11-12 | Release date: | 2019-01-23 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Molecular mechanisms of gating in the calcium-activated chloride channel bestrophin. Elife, 8, 2019
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6N24
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6N26
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![BU of 6n26 by Molmil](/molmil-images/mine/6n26) | BEST1 calcium-free closed state | Descriptor: | Bestrophin homolog | Authors: | Miller, A.N, Vaisey, G, Long, S.B. | Deposit date: | 2018-11-12 | Release date: | 2019-01-23 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Molecular mechanisms of gating in the calcium-activated chloride channel bestrophin. Elife, 8, 2019
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6N23
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6N28
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![BU of 6n28 by Molmil](/molmil-images/mine/6n28) | BEST1 calcium-bound open state | Descriptor: | Bestrophin homolog, CALCIUM ION | Authors: | Miller, A.N, Vaisey, G, Long, S.B. | Deposit date: | 2018-11-12 | Release date: | 2019-01-23 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Molecular mechanisms of gating in the calcium-activated chloride channel bestrophin. Elife, 8, 2019
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6N25
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4RDQ
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![BU of 4rdq by Molmil](/molmil-images/mine/4rdq) | Calcium-activated chloride channel bestrophin-1, from chicken, in complex with Fab antibody fragments, chloride and calcium | Descriptor: | 6-cyclohexyl-2-(4-cyclohexylbutyl)-2-({[4-O-(alpha-D-glucopyranosyl)-beta-D-glucopyranosyl]oxy}methyl)hexyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, Bestrophin-1, CALCIUM ION, ... | Authors: | Dickson, V.K, Pedi, L, Long, S.B. | Deposit date: | 2014-09-19 | Release date: | 2014-10-22 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structure and insights into the function of a Ca(2+)-activated Cl(-) channel. Nature, 516, 2014
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3LUT
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![BU of 3lut by Molmil](/molmil-images/mine/3lut) | A Structural Model for the Full-length Shaker Potassium Channel Kv1.2 | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, Potassium voltage-gated channel subfamily A member 2, ... | Authors: | Chen, X, Ni, F, Wang, Q, Ma, J. | Deposit date: | 2010-02-18 | Release date: | 2010-06-23 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of the full-length Shaker potassium channel Kv1.2 by normal-mode-based X-ray crystallographic refinement. Proc.Natl.Acad.Sci.USA, 107, 2010
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