5T5N

Calcium-activated chloride channel bestrophin-1 (BEST1), triple mutant: I76A, F80A, F84A; in complex with an Fab antibody fragment, chloride, and calcium

Summary for 5T5N

• Entry DOI: 10.2210/pdb5t5n/pdb
• Descriptor: bestrophin-1 (BEST1), Fab antibody fragment, light chain (10D10), Fab antibody fragment, heavy chain (10D10), ... (8 entities in total)
• Functional Keywords: ion channel, anion, chloride, calcium-activated, eukaryotic membrane protein, cacc, membrane protein
• Biological source: Gallus gallus (Chicken); More
• Total number of polymer chains: 15
• Total formula weight: 473379.65

Authors

Long, S.B.,Vaisey, G. (deposition date: 2016-08-31, release date: 2016-11-30, Last modification date: 2023-10-04)

• Primary citation: Vaisey, G.,Miller, A.N.,Long, S.B.; Distinct regions that control ion selectivity and calcium-dependent activation in the bestrophin ion channel.; Proc. Natl. Acad. Sci. U.S.A., 113:E7399-E7408, 2016; PubMed: 27821745; DOI: 10.1073/pnas.1614688113

Experimental method

X-RAY DIFFRACTION (3.1 Å)