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1TR7
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BU of 1tr7 by Molmil
FimH adhesin receptor binding domain from uropathogenic E. coli
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, FimH protein, ...
Authors:Bouckaert, J, Berglund, J, Schembri, M, De Genst, E, Cools, L, Wuhrer, M, Hung, C.S, Pinkner, J, Slattegard, R, Zavialov, A, Choudhury, D, Langermann, S, Hultgren, S.J, Wyns, L, Klemm, P, Oscarson, S, Knight, S.D, De Greve, H.
Deposit date:2004-06-21
Release date:2005-05-03
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Receptor binding studies disclose a novel class of high-affinity inhibitors of the Escherichia coli FimH adhesin
Mol.Microbiol., 55, 2005
3PNT
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BU of 3pnt by Molmil
Crystal Structure of the Streptococcus pyogenes NAD+ glycohydrolase SPN in complex with IFS, the Immunity Factor for SPN
Descriptor: Immunity factor for SPN, NAD+-glycohydrolase
Authors:Smith, C.L, Stine Elam, J, Ellenberger, T, Ghosh, J, Pinkner, J.S, Hultgren, S.J, Caparon, M.G.
Deposit date:2010-11-19
Release date:2011-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis of Streptococcus pyogenes Immunity to Its NAD(+) Glycohydrolase Toxin.
Structure, 19, 2011
1QPP
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BU of 1qpp by Molmil
CRYSTAL STRUCTURES OF SELF CAPPING PAPD CHAPERONE HOMODIMERS
Descriptor: PAPD CHAPERONE
Authors:Hung, D.L, Pinkner, J.S, Knight, S.D, Hultgren, S.J.
Deposit date:1999-05-28
Release date:1999-07-07
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of chaperone self-capping in P pilus biogenesis.
Proc.Natl.Acad.Sci.USA, 96, 1999
1QPX
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BU of 1qpx by Molmil
CRYSTAL STRUCTURES OF SELF-CAPPING PAPD CHAPERONE HOMODIMERS
Descriptor: PAPD CHAPERONE
Authors:Hung, D.L, Pinkner, J.S, Knight, S.D, Hultgren, S.J.
Deposit date:1999-05-31
Release date:1999-07-07
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of chaperone self-capping in P pilus biogenesis.
Proc.Natl.Acad.Sci.USA, 96, 1999
1QUN
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BU of 1qun by Molmil
X-RAY STRUCTURE OF THE FIMC-FIMH CHAPERONE ADHESIN COMPLEX FROM UROPATHOGENIC E.COLI
Descriptor: MANNOSE-SPECIFIC ADHESIN FIMH, PAPD-LIKE CHAPERONE FIMC
Authors:Choudhury, D, Thompson, A, Stojanoff, V, Langerman, S, Pinkner, J, Hultgren, S.J, Knight, S.
Deposit date:1999-07-01
Release date:1999-08-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:X-ray structure of the FimC-FimH chaperone-adhesin complex from uropathogenic Escherichia coli.
Science, 285, 1999
1PDK
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BU of 1pdk by Molmil
PAPD-PAPK CHAPERONE-PILUS SUBUNIT COMPLEX FROM E.COLI P PILUS
Descriptor: PROTEIN (CHAPERONE PROTEIN PAPD), PROTEIN (PROTEIN PAPK)
Authors:Fuetterer, K, Sauer, F.G, Hultgren, S.J, Waksman, G.
Deposit date:1999-03-29
Release date:1999-08-17
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of chaperone function and pilus biogenesis.
Science, 285, 1999
2VCO
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BU of 2vco by Molmil
Crystal structure of the fimbrial adhesin FimH in complex with its high-mannose epitope
Descriptor: NICKEL (II) ION, PROTEIN FIMH, SULFATE ION, ...
Authors:Wellens, A, Garofalo, C, Nguyen, H, Wyns, L, De Greve, H, Hultgren, S.J, Bouckaert, J.
Deposit date:2007-09-26
Release date:2008-05-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Intervening with Urinary Tract Infections Using Anti-Adhesives Based on the Crystal Structure of the Fimh-Oligomannose-3 Complex.
Plos One, 3, 2008
2UY7
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BU of 2uy7 by Molmil
Crystal structure of the P pilus rod subunit PapA
Descriptor: PAP FIMBRIAL MAJOR PILIN PROTEIN, PERIPLASMID CHAPERONE PAPD PROTEIN, SULFATE ION
Authors:Verger, D, Bullitt, E, Hultgren, S.J, Waksman, G.
Deposit date:2007-04-02
Release date:2007-05-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the P Pilus Rod Subunit Papa.
Plos Pathog., 3, 2007
2UY6
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BU of 2uy6 by Molmil
Crystal structure of the P pilus rod subunit PapA
Descriptor: PAP FIMBRIAL MAJOR PILIN PROTEIN, PERIPLASMID CHAPERONE PAPD PROTEIN
Authors:Verger, D, Bullitt, E, Hultgren, S.J, Waksman, G.
Deposit date:2007-04-02
Release date:2007-05-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of the P Pilus Rod Subunit Papa.
Plos Pathog., 3, 2007
2VQI
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BU of 2vqi by Molmil
Structure of the P pilus usher (PapC) translocation pore
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, LAURYL DIMETHYLAMINE-N-OXIDE, OUTER MEMBRANE USHER PROTEIN PAPC
Authors:Remaut, H, Tang, C, Henderson, N.S, Pinkner, J.S, Wang, T, Hultgren, S.J, Thanassi, D.G, Li, H, Waksman, G.
Deposit date:2008-03-16
Release date:2008-05-27
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Fiber formation across the bacterial outer membrane by the chaperone/usher pathway.
Cell, 133, 2008
2CO3
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BU of 2co3 by Molmil
Salmonella enterica SafA pilin, head-to-tail swapped dimer of Ntd1 mutant
Descriptor: SAFA PILUS SUBUNIT
Authors:Remaut, H, Rose, R.J, Hannan, T.J, Hultgren, S.J, Radford, S.E, Ashcroft, A.E, Waksman, G.
Deposit date:2006-05-25
Release date:2006-06-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Donor-Strand Exchange in Chaperone-Assisted Pilus Assembly Proceeds Through a Concerted Beta-Strand Displacement Mechanism
Mol.Cell, 22, 2006
2CO6
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BU of 2co6 by Molmil
Salmonella enterica SafA pilin in complex with the SafB chaperone (Type I)
Descriptor: PUTATIVE FIMBRIAE ASSEMBLY CHAPERONE, PUTATIVE OUTER MEMBRANE PROTEIN
Authors:Remaut, H, Rose, R.J, Hannan, T.J, Hultgren, S.J, Radford, S.E, Ashcroft, A.E, Waksman, G.
Deposit date:2006-05-25
Release date:2006-06-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Donor-Strand Exchange in Chaperone-Assisted Pilus Assembly Proceeds Through a Concerted Beta-Strand Displacement Mechanism
Mol.Cell, 22, 2006
2CO4
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BU of 2co4 by Molmil
Salmonella enterica SafA pilin in complex with a 19-residue SafA Nte peptide
Descriptor: PUTATIVE OUTER MEMBRANE PROTEIN
Authors:Remaut, H, Rose, R.J, Hannan, T.J, Hultgren, S.J, Radford, S.E, Ashcroft, A.E, Waksman, G.
Deposit date:2006-05-25
Release date:2006-06-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Donor-Strand Exchange in Chaperone-Assisted Pilus Assembly Proceeds Through a Concerted Beta-Strand Displacement Mechanism
Mol.Cell, 22, 2006
2CO2
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BU of 2co2 by Molmil
Salmonella enterica SafA pilin in complex with a 19-residue SafA Nte peptide (F3A mutant)
Descriptor: SAFA N-TERMINAL EXTENSION, SAFA PILUS SUBUNIT
Authors:Remaut, H, Rose, R.J, Hannan, T.J, Hultgren, S.J, Radford, S.E, Ashcroft, A.E, Waksman, G.
Deposit date:2006-05-25
Release date:2006-06-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Donor-Strand Exchange in Chaperone-Assisted Pilus Assembly Proceeds Through a Concerted Beta-Strand Displacement Mechanism
Mol.Cell, 22, 2006
2CNY
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BU of 2cny by Molmil
Salmonella enterica SafA pilin in complex with a 19-residue SafA Nte peptide (I15A mutant)
Descriptor: PUTATIVE OUTER MEMBRANE PROTEIN
Authors:Remaut, H, Rose, R.J, Hannan, T.J, Hultgren, S.J, Radford, S.E, Ashcroft, A.E, Waksman, G.
Deposit date:2006-05-25
Release date:2006-06-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Donor-Strand Exchange in Chaperone-Assisted Pilus Assembly Proceeds Through a Concerted Beta-Strand Displacement Mechanism
Mol.Cell, 22, 2006
2CO1
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BU of 2co1 by Molmil
Salmonella enterica SafA pilin in complex with a 19-residue SafA Nte peptide (F17A mutant)
Descriptor: PUTATIVE OUTER MEMBRANE PROTEIN
Authors:Remaut, H, Rose, R.J, Hannan, T.J, Hultgren, S.J, Radford, S.E, Ashcroft, A.E, Waksman, G.
Deposit date:2006-05-25
Release date:2006-06-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Donor-Strand Exchange in Chaperone-Assisted Pilus Assembly Proceeds Through a Concerted Beta-Strand Displacement Mechanism
Mol.Cell, 22, 2006
2CNZ
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BU of 2cnz by Molmil
Salmonella enterica SafA pilin in complex with a 19-residue SafA Nte peptide (V13A mutant)
Descriptor: PUTATIVE OUTER MEMBRANE PROTEIN
Authors:Remaut, H, Rose, R.J, Hannan, T.J, Hultgren, S.J, Radford, S.E, Ashcroft, A.E, Waksman, G.
Deposit date:2006-05-25
Release date:2006-06-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Donor-Strand Exchange in Chaperone-Assisted Pilus Assembly Proceeds Through a Concerted Beta-Strand Displacement Mechanism
Mol.Cell, 22, 2006
2CO7
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BU of 2co7 by Molmil
Salmonella enterica SafA pilin in complex with the SafB chaperone (Type II)
Descriptor: PUTATIVE FIMBRIAE ASSEMBLY CHAPERONE, SAFA PILUS SUBUNIT, SULFATE ION
Authors:Remaut, H, Rose, R.J, Hannan, T.J, Hultgren, S.J, Radford, S.E, Ashcroft, A.E, Waksman, G.
Deposit date:2006-05-25
Release date:2006-06-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Donor-Strand Exchange in Chaperone-Assisted Pilus Assembly Proceeds Through a Concerted Beta-Strand Displacement Mechanism
Mol.Cell, 22, 2006
6AOW
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BU of 6aow by Molmil
Crystal structure of lectin domain of F9 pilus adhesin FmlH from E. coli UTI89
Descriptor: F9 pilus adhesin FmlH, SULFATE ION
Authors:Kalas, V, Hultgren, S.J.
Deposit date:2017-08-16
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection.
Proc.Natl.Acad.Sci.USA, 115, 2018
6AOX
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BU of 6aox by Molmil
F9 pilus adhesin FmlH lectin domain from E. coli UTI89 co-crystallized with TF antigen
Descriptor: Fml fimbrial adhesin FmlD, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose
Authors:Kalas, V, Hultgren, S.J.
Deposit date:2017-08-16
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection.
Proc.Natl.Acad.Sci.USA, 115, 2018
6AS8
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BU of 6as8 by Molmil
F9 pilus adhesin FmlH lectin domain from E. coli UTI89 co-crystallized with ortho-biphenyl-2'-carboxyl N-acetyl-beta-galactosaminoside
Descriptor: Fml fimbrial adhesin FmlD, ortho-biphenyl-2'-carboxyl N-acetyl-beta-galactosaminoside
Authors:Kalas, V, Hultgren, S.J.
Deposit date:2017-08-23
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection.
Proc.Natl.Acad.Sci.USA, 115, 2018
6ARO
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BU of 6aro by Molmil
F9 pilus adhesin FmlH lectin domain from E. coli UTI89 co-crystallized with 8-hydroxyquinoline beta-galactoside
Descriptor: 8-hydroxyquinoline beta-galactopyranoside, F9 pilus adhesin FmlH, SULFATE ION
Authors:Kalas, V, Hultgren, S.J.
Deposit date:2017-08-23
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection.
Proc.Natl.Acad.Sci.USA, 115, 2018
1J8S
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BU of 1j8s by Molmil
PAPG ADHESIN RECEPTOR BINDING DOMAIN-UNBOUND FORM
Descriptor: PYELONEPHRITIC ADHESIN
Authors:Dodson, K.W, Pinkner, J.S, Rose, T, Magnusson, G, Hultgren, S.J, Waksman, G.
Deposit date:2001-05-22
Release date:2001-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of the interaction of the pyelonephritic E. coli adhesin to its human kidney receptor.
Cell(Cambridge,Mass.), 105, 2001
6ARM
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BU of 6arm by Molmil
F9 pilus adhesin FmlH lectin domain from E. coli UTI89 co-crystallized with o-nitrophenyl beta-galactoside (ONPG)
Descriptor: 2-nitrophenyl beta-D-galactopyranoside, F9 pilus adhesin FmlH, SULFATE ION
Authors:Kalas, V, Hultgren, S.J.
Deposit date:2017-08-22
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection.
Proc.Natl.Acad.Sci.USA, 115, 2018
6ARN
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BU of 6arn by Molmil
F9 pilus adhesin FmlH lectin domain from E. coli UTI89 co-crystallized with o-methoxyphenyl beta-galactoside (OMPG)
Descriptor: 2-methoxyphenyl beta-D-galactopyranoside, Putative Fml fimbrial adhesin FmlD, SULFATE ION
Authors:Kalas, V, Hultgren, S.J.
Deposit date:2017-08-22
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection.
Proc.Natl.Acad.Sci.USA, 115, 2018

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