4I2G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4i2g by Molmil](/molmil-images/mine/4i2g) | Binary complex of mouse TdT with ssDNA | Descriptor: | 5'-D(P*AP*AP*AP*AP*A)-3', COBALT (II) ION, DNA nucleotidylexotransferase, ... | Authors: | Gouge, J, Delarue, M. | Deposit date: | 2012-11-21 | Release date: | 2013-07-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism. J.Mol.Biol., 425, 2013
|
|
4I2A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4i2a by Molmil](/molmil-images/mine/4i2a) | |
4I2J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4i2j by Molmil](/molmil-images/mine/4i2j) | Binary complex of mouse TdT with dCTP | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA nucleotidylexotransferase, ZINC ION | Authors: | Gouge, J, Delarue, M. | Deposit date: | 2012-11-21 | Release date: | 2013-07-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism. J.Mol.Biol., 425, 2013
|
|
4I2H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4i2h by Molmil](/molmil-images/mine/4i2h) | Ternary complex of mouse TdT with ssDNA and AMPcPP | Descriptor: | 5'-D(P*AP*AP*AP*AP*A)-3', DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA nucleotidylexotransferase, ... | Authors: | Gouge, J, Delarue, M. | Deposit date: | 2012-11-21 | Release date: | 2013-07-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism. J.Mol.Biol., 425, 2013
|
|
4I2E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4i2e by Molmil](/molmil-images/mine/4i2e) | Ternary complex of mouse TdT with ssDNA and AMPcPP | Descriptor: | 5'-D(*AP*AP*AP*AP*A)-3', COBALT (II) ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... | Authors: | Gouge, J, Delarue, M. | Deposit date: | 2012-11-21 | Release date: | 2013-07-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism. J.Mol.Biol., 425, 2013
|
|
4I27
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4i27 by Molmil](/molmil-images/mine/4i27) | Ternary complex of mouse TdT with ssDNA and incoming nucleotide | Descriptor: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*AP*AP*AP*AP*T)-3', DNA nucleotidylexotransferase, ... | Authors: | Gouge, J, Delarue, M. | Deposit date: | 2012-11-21 | Release date: | 2013-07-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism. J.Mol.Biol., 425, 2013
|
|
4I2I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4i2i by Molmil](/molmil-images/mine/4i2i) | Binary complex of mouse TdT with AP5A | Descriptor: | BIS(ADENOSINE)-5'-PENTAPHOSPHATE, DNA nucleotidylexotransferase, MAGNESIUM ION, ... | Authors: | Gouge, J, Delarue, M. | Deposit date: | 2012-11-21 | Release date: | 2013-07-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism. J.Mol.Biol., 425, 2013
|
|
4I2F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4i2f by Molmil](/molmil-images/mine/4i2f) | Binary complex of mouse TdT with ssDNA | Descriptor: | 5'-D(P*AP*AP*AP*AP*A)-3', DNA nucleotidylexotransferase, MAGNESIUM ION, ... | Authors: | Gouge, J, Delarue, M. | Deposit date: | 2012-11-21 | Release date: | 2013-07-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism. J.Mol.Biol., 425, 2013
|
|
4I28
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4i28 by Molmil](/molmil-images/mine/4i28) | Binary complex of mouse TdT with ssDNA and Zn++ | Descriptor: | 5'-D(*AP*AP*AP*AP*A)-3', DNA nucleotidylexotransferase, MAGNESIUM ION, ... | Authors: | Gouge, J, Delarue, M. | Deposit date: | 2012-11-21 | Release date: | 2013-07-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism. J.Mol.Biol., 425, 2013
|
|
4I2C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4i2c by Molmil](/molmil-images/mine/4i2c) | Ternary complex of mouse TdT with ssDNA and AMPcPP | Descriptor: | 5'-D(*AP*AP*AP*AP*A)-3', DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA nucleotidylexotransferase, ... | Authors: | Gouge, J, Delarue, M. | Deposit date: | 2012-11-21 | Release date: | 2013-07-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism. J.Mol.Biol., 425, 2013
|
|
8OOV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8oov by Molmil](/molmil-images/mine/8oov) | human NME-1 in complex with CoA | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3'-PHOSPHATE-ADENOSINE-5'-DIPHOSPHATE, Nucleoside diphosphate kinase A | Authors: | Gouge, J, Hristov, H.D. | Deposit date: | 2023-04-06 | Release date: | 2023-06-07 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A Unique Mode of Coenzyme A Binding to the Nucleotide Binding Pocket of Human Metastasis Suppressor NME1. Int J Mol Sci, 24, 2023
|
|
4ROE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4roe by Molmil](/molmil-images/mine/4roe) | Human TFIIB-related factor 2 (Brf2) and TBP bound to RPPH1 promoter | Descriptor: | MAGNESIUM ION, Non-template strand, TATA-box-binding protein, ... | Authors: | Vannini, A, Gouge, J, Satia, K, Guthertz, N. | Deposit date: | 2014-10-28 | Release date: | 2015-12-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2. Cell(Cambridge,Mass.), 163, 2015
|
|
4ROD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4rod by Molmil](/molmil-images/mine/4rod) | Human TFIIB-related factor 2 (Brf2) and TBP bound to TRNAU1 promoter | Descriptor: | Non-template strand, TATA-box-binding protein, Template strand, ... | Authors: | Vannini, A, Gouge, J, Satia, K, Guthertz, N. | Deposit date: | 2014-10-28 | Release date: | 2015-12-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2. Cell(Cambridge,Mass.), 163, 2015
|
|
4ROC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4roc by Molmil](/molmil-images/mine/4roc) | Human TFIIB-related factor 2 (Brf2) and TBP bound to U6#2 promoter | Descriptor: | MAGNESIUM ION, Non-template strand, TATA-box-binding protein, ... | Authors: | Vannini, A, Gouge, J, Satia, K, Guthertz, N. | Deposit date: | 2014-10-28 | Release date: | 2015-12-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2. Cell(Cambridge,Mass.), 163, 2015
|
|
4IQT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4iqt by Molmil](/molmil-images/mine/4iqt) | Tdt core in complex with inhibitor 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid | Descriptor: | 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid, DNA nucleotidylexotransferase | Authors: | Gouge, J, Delarue, M. | Deposit date: | 2013-01-13 | Release date: | 2013-09-04 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target. J.Med.Chem., 56, 2013
|
|
4IQU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4iqu by Molmil](/molmil-images/mine/4iqu) | Tdt core in complex with inhibitor (2Z,5E)-6-[4-(4-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid | Descriptor: | (2Z,5E)-6-[4-(4-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid, DNA nucleotidylexotransferase, SODIUM ION | Authors: | Gouge, J, Delarue, M. | Deposit date: | 2013-01-13 | Release date: | 2013-09-04 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target. J.Med.Chem., 56, 2013
|
|
4IQV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4iqv by Molmil](/molmil-images/mine/4iqv) | Tdt core in complex with inhibitor 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid and ssDNA | Descriptor: | 5'-D(*GP*CP*CP*G)-3', 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid, DNA nucleotidylexotransferase, ... | Authors: | Gouge, J, Delarue, M. | Deposit date: | 2013-01-13 | Release date: | 2013-09-04 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target. J.Med.Chem., 56, 2013
|
|
4IQW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4iqw by Molmil](/molmil-images/mine/4iqw) | Tdt core in complex with inhibitor (2Z,5E)-6-[4-(4-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid and ssDNA | Descriptor: | (2Z,5E)-6-[4-(4-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid, 5'-D(*GP*CP*CP*G)-3', DNA nucleotidylexotransferase, ... | Authors: | Gouge, J, Delarue, M. | Deposit date: | 2013-01-13 | Release date: | 2013-09-04 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target. J.Med.Chem., 56, 2013
|
|
7ZX8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zx8 by Molmil](/molmil-images/mine/7zx8) | Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (OC) | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | Authors: | Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P. | Deposit date: | 2022-05-20 | Release date: | 2022-12-07 | Last modified: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nat.Struct.Mol.Biol., 29, 2022
|
|
7ZWD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zwd by Molmil](/molmil-images/mine/7zwd) | Structure of SNAPc containing Pol II pre-initiation complex bound to U5 snRNA promoter (CC) | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | Authors: | Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P. | Deposit date: | 2022-05-19 | Release date: | 2022-11-30 | Last modified: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nat.Struct.Mol.Biol., 29, 2022
|
|
7ZX7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zx7 by Molmil](/molmil-images/mine/7zx7) | Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (CC) | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | Authors: | Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P. | Deposit date: | 2022-05-20 | Release date: | 2022-11-30 | Last modified: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nat.Struct.Mol.Biol., 29, 2022
|
|
7ZXE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zxe by Molmil](/molmil-images/mine/7zxe) | Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (OC) | Descriptor: | Non-template strand, TATA-box-binding protein, Template strand, ... | Authors: | Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P. | Deposit date: | 2022-05-20 | Release date: | 2022-11-30 | Last modified: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nat.Struct.Mol.Biol., 29, 2022
|
|
7AST
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ast by Molmil](/molmil-images/mine/7ast) | Apo Human RNA Polymerase III | Descriptor: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | Authors: | Ramsay, E.P, Abascal-Palacios, G, Daiss, J.L, King, H, Gouge, J, Pilsl, M, Beuron, F, Morris, E, Gunkel, P, Engel, C, Vannini, A. | Deposit date: | 2020-10-28 | Release date: | 2020-12-23 | Last modified: | 2020-12-30 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structure of human RNA polymerase III. Nat Commun, 11, 2020
|
|
7ZWC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zwc by Molmil](/molmil-images/mine/7zwc) | Structure of SNAPc:TBP-TFIIA-TFIIB sub-complex bound to U5 snRNA promoter | Descriptor: | Non-template strand, TATA-box-binding protein, Template strand, ... | Authors: | Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P. | Deposit date: | 2022-05-19 | Release date: | 2022-11-30 | Last modified: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nat.Struct.Mol.Biol., 29, 2022
|
|
7ASV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7asv by Molmil](/molmil-images/mine/7asv) | |