6UMJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6umj by Molmil](/molmil-images/mine/6umj) | Crystal structure of erenumab Fab-c | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,3-BUTANEDIOL, erenumab Fab heavy chain, ... | Authors: | Mohr, C. | Deposit date: | 2019-10-09 | Release date: | 2020-02-12 | Last modified: | 2020-02-26 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Molecular Insight into Recognition of the CGRPR Complex by Migraine Prevention Therapy Aimovig (Erenumab). Cell Rep, 30, 2020
|
|
5WDU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wdu by Molmil](/molmil-images/mine/5wdu) | HIV-1 Env BG505 SOSIP.664 H72C-H564C trimer in complex with bNAbs PGT122 Fab, 35O22 Fab and NIH45-46 scFv | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | Authors: | Julien, J.-P, Torrents de la Pena, A, Sanders, R.W, Wilson, I.A. | Deposit date: | 2017-07-06 | Release date: | 2018-04-04 | Last modified: | 2022-11-30 | Method: | X-RAY DIFFRACTION (7 Å) | Cite: | Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization. Cell Rep, 20, 2017
|
|
6OHY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ohy by Molmil](/molmil-images/mine/6ohy) | Chimpanzee SIV Env trimeric ectodomain. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Pallesen, J, Andrabi, R, de Val, N, Burton, D.R, Ward, A.B. | Deposit date: | 2019-04-08 | Release date: | 2019-06-05 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | The Chimpanzee SIV Envelope Trimer: Structure and Deployment as an HIV Vaccine Template. Cell Rep, 27, 2019
|
|
6IEQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ieq by Molmil](/molmil-images/mine/6ieq) | Crystal Structure of HIV-1 Env ConM SOSIP.v7 in Complex with bNAb PGT124 and 35O22 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Fab Heavy Chain, ... | Authors: | Han, B.W, Wilson, I.A. | Deposit date: | 2018-09-16 | Release date: | 2019-05-22 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence. Nat Commun, 10, 2019
|
|
4RNR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4rnr by Molmil](/molmil-images/mine/4rnr) | Crystal structure of broadly neutralizing anti-HIV antibody PGT130 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PGT130 Heavy Chain, PGT130 Light Chain | Authors: | Kong, L, Wilson, I.A. | Deposit date: | 2014-10-24 | Release date: | 2014-11-19 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.758 Å) | Cite: | Two Classes of Broadly Neutralizing Antibodies within a Single Lineage Directed to the High-Mannose Patch of HIV Envelope. J.Virol., 89, 2015
|
|
5T3S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5t3s by Molmil](/molmil-images/mine/5t3s) | HIV gp140 trimer MD39-10MUTA in complex with Fabs PGT124 and 35022 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2016-08-26 | Release date: | 2016-09-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (4.5 Å) | Cite: | HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies. Immunity, 45, 2016
|
|
5CD5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5cd5 by Molmil](/molmil-images/mine/5cd5) | |
5C7K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5c7k by Molmil](/molmil-images/mine/5c7k) | Crystal structure BG505 SOSIP gp140 HIV-1 Env trimer bound to broadly neutralizing antibodies PGT128 and 8ANC195 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab 8ANC195 heavy chain, ... | Authors: | Kong, L, Stanfield, R.L, Wilson, I.A. | Deposit date: | 2015-06-24 | Release date: | 2015-10-07 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (4.6019 Å) | Cite: | Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer. Acta Crystallogr.,Sect.D, 71, 2015
|
|
5CD3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5cd3 by Molmil](/molmil-images/mine/5cd3) | Structure of immature VRC01-class antibody DRVIA7 | Descriptor: | DRVIA7 Heavy Chain, DRVIA7 Light Chain | Authors: | Kong, L, Wilson, I.A. | Deposit date: | 2015-07-02 | Release date: | 2016-04-06 | Last modified: | 2018-09-05 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor. Immunity, 44, 2016
|
|