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8GA0
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BU of 8ga0 by Molmil
CLC-ec1 E202Y at pH 4.5 100mM Cl Turn
Descriptor: H(+)/Cl(-) exchange transporter ClcA
Authors:Fortea, E, Lee, S, Argyos, Y, Chadda, R, Ciftci, D, Huysmans, G, Robertson, J.L, Boudker, O, Accardi, A.
Deposit date:2023-02-22
Release date:2024-02-07
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of pH-dependent activation in a CLC transporter.
Nat.Struct.Mol.Biol., 31, 2024
8GAH
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BU of 8gah by Molmil
CLC-ec1 L25C/A450C/C85A at pH 4.5 100mM Cl Twist
Descriptor: CHLORIDE ION, H(+)/Cl(-) exchange transporter ClcA
Authors:Fortea, E, Lee, S, Argyos, Y, Chadda, R, Ciftci, D, Huysmans, G, Robertson, J.L, Boudker, O, Accardi, A.
Deposit date:2023-02-22
Release date:2024-02-07
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of pH-dependent activation in a CLC transporter.
Nat.Struct.Mol.Biol., 31, 2024
8GA3
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BU of 8ga3 by Molmil
CLC-ec1 R230C/L249C/C85A at pH 4.5 100mM Cl Turn
Descriptor: CHLORIDE ION, H(+)/Cl(-) exchange transporter ClcA
Authors:Fortea, E, Lee, S, Argyos, Y, Chadda, R, Ciftci, D, Huysmans, G, Robertson, J.L, Boudker, O, Accardi, A.
Deposit date:2023-02-22
Release date:2024-02-07
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of pH-dependent activation in a CLC transporter.
Nat.Struct.Mol.Biol., 31, 2024
8GA1
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BU of 8ga1 by Molmil
CLC-ec1 R230C/L249C/C85A at pH 4.5 100mM Cl Swap
Descriptor: CHLORIDE ION, H(+)/Cl(-) exchange transporter ClcA
Authors:Fortea, E, Lee, S, Argyos, Y, Chadda, R, Ciftci, D, Huysmans, G, Robertson, J.L, Boudker, O, Accardi, A.
Deposit date:2023-02-22
Release date:2024-02-07
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural basis of pH-dependent activation in a CLC transporter.
Nat.Struct.Mol.Biol., 31, 2024
8GA5
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BU of 8ga5 by Molmil
CLC-ec1 L25C/A450C/C85A at pH 4.5 100mM Cl Intermediate
Descriptor: CHLORIDE ION, H(+)/Cl(-) exchange transporter ClcA
Authors:Fortea, E, Lee, S, Argyos, Y, Chadda, R, Ciftci, D, Huysmans, G, Robertson, J.L, Boudker, O, Accardi, A.
Deposit date:2023-02-22
Release date:2024-02-07
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural basis of pH-dependent activation in a CLC transporter.
Nat.Struct.Mol.Biol., 31, 2024
4IYS
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BU of 4iys by Molmil
Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4
Descriptor: Metal transporter CNNM2
Authors:Corral-Rodriguez, M.A, Stuiver, M, Encinar, J.A, Spiwok, V, Gomez-Garcia, I, Oyenarte, I, Ereno-Orbea, J, Terashima, H, Accardi, A, Diercks, T, Muller, D, Martinez-Cruz, L.A.
Deposit date:2013-01-29
Release date:2014-03-05
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4
To be Published
4IY2
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BU of 4iy2 by Molmil
Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4
Descriptor: Metal transporter CNNM2
Authors:Corral-Rodriguez, M.A, Stuiver, M, Encinar, J.A, Spiwok, V, Gomez-Garcia, I, Oyenarte, I, Ereno-Orbea, J, Terashima, H, Accardi, A, Diercks, T, Muller, D, Martinez-Cruz, L.A.
Deposit date:2013-01-28
Release date:2014-03-05
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4
To be Published
4IY0
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BU of 4iy0 by Molmil
Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4
Descriptor: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, Metal transporter CNNM2
Authors:Corral-Rodriguez, M.A, Stuiver, M, Encinar, J.A, Spiwok, V, Gomez-Garcia, I, Oyenarte, I, Ereno-Orbea, J, Terashima, H, Accardi, A, Diercks, T, Muller, D, Martinez-Cruz, L.A.
Deposit date:2013-01-28
Release date:2014-03-05
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4
To be Published
4IY4
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BU of 4iy4 by Molmil
Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4
Descriptor: Metal transporter CNNM2
Authors:Corral-Rodriguez, M.A, Stuiver, M, Encinar, J.A, Spiwok, V, Gomez-Garcia, I, Oyenarte, I, Ereno-Orbea, J, Terashima, H, Accardi, A, Diercks, T, Muller, D, Martinez-Cruz, L.A.
Deposit date:2013-01-28
Release date:2014-03-12
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4
To be Published
6OY3
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BU of 6oy3 by Molmil
nhTMEM16 L302A +Ca2+ in nanodiscs
Descriptor: CALCIUM ION, nhTMEM16
Authors:Falzone, M, Lee, B.C, Accardi, A.
Deposit date:2019-05-14
Release date:2019-11-06
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Dynamic modulation of the lipid translocation groove generates a conductive ion channel in Ca 2+ -bound nhTMEM16.
Nat Commun, 10, 2019
7RNX
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BU of 7rnx by Molmil
CLC-ec1 at pH 7.5 100mM Cl Swap
Descriptor: H(+)/Cl(-) exchange transporter ClcA
Authors:Fortea, E, Boudker, O, Accardi, A.
Deposit date:2021-07-30
Release date:2022-11-16
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:Structural basis of common gate activation in CLC transporters
To Be Published
7RP6
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BU of 7rp6 by Molmil
CLC-ec1 at pH 4.5 100 mM NaGluconate Swap
Descriptor: H(+)/Cl(-) exchange transporter ClcA
Authors:Fortea, E, Boudker, O, Accardi, A.
Deposit date:2021-08-03
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.78 Å)
Cite:Structural basis of common gate activation in CLC transporters
To Be Published
7RO0
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BU of 7ro0 by Molmil
CLC-ec1 at pH 7.5 100 mM NaGluconate Swap
Descriptor: H(+)/Cl(-) exchange transporter ClcA
Authors:Fortea, E, Boudker, O, Accardi, A.
Deposit date:2021-07-30
Release date:2022-11-16
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Structural basis of common gate activation in CLC transporters
To Be Published
7RSB
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BU of 7rsb by Molmil
CLC-ec1 at pH 4.5 100 mM NaGluconate Turn
Descriptor: H(+)/Cl(-) exchange transporter ClcA
Authors:Fortea, E, Boudker, O, Accardi, A.
Deposit date:2021-08-11
Release date:2022-11-16
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:Structural basis of common gate activation in CLC transporters
To Be Published
7RP5
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BU of 7rp5 by Molmil
CLC-ec1 at pH 4.5 100mM Cl Turn
Descriptor: H(+)/Cl(-) exchange transporter ClcA
Authors:Fortea, E, Boudker, O, Accardi, A.
Deposit date:2021-08-03
Release date:2022-11-16
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:Structural basis of common gate activation in CLC transporters
To Be Published
7RQ7
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BU of 7rq7 by Molmil
CLC-ec1 at pH 4.5 100mM Cl TWIST2
Descriptor: H(+)/Cl(-) exchange transporter ClcA
Authors:Fortea, E, Boudker, O, Accardi, A.
Deposit date:2021-08-05
Release date:2022-11-16
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.95 Å)
Cite:Structural basis of common gate activation in CLC transporters
To Be Published
8TPO
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BU of 8tpo by Molmil
nhTMEM16 R432A mutant in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, Lipid scramblase nhTMEM16
Authors:Feng, Z, Accardi, A.
Deposit date:2023-08-04
Release date:2024-05-15
Method:ELECTRON MICROSCOPY (3.59 Å)
Cite:Structural basis of closed groove scrambling by a TMEM16 protein.
Nat.Struct.Mol.Biol., 2024
8TOK
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BU of 8tok by Molmil
nhTMEM16 lipid scramblase in lipid nanodiscs with MSP2N2 scaffold protein in the presence of Ca2+ (open state)
Descriptor: CALCIUM ION, Lipid scramblase nhTMEM16
Authors:Feng, Z, Accardi, A.
Deposit date:2023-08-03
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (3.84 Å)
Cite:Structural basis of closed groove scrambling by a TMEM16 protein.
Nat.Struct.Mol.Biol., 2024
8TPQ
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BU of 8tpq by Molmil
nhTMEM16 A444P mutant in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+ (long TM6)
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, Lipid scramblase nhTMEM16
Authors:Feng, Z, Accardi, A.
Deposit date:2023-08-04
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Structural basis of closed groove scrambling by a TMEM16 protein.
Nat.Struct.Mol.Biol., 2024
8TPR
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BU of 8tpr by Molmil
nhTMEM16 A444P mutant in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+ (short TM6)
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, Lipid scramblase nhTMEM16
Authors:Feng, Z, Accardi, A.
Deposit date:2023-08-04
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Structural basis of closed groove scrambling by a TMEM16 protein.
Nat.Struct.Mol.Biol., 2024
8TPM
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BU of 8tpm by Molmil
nhTMEM16 lipid scramblase in lipid nanodiscs with MSP1E3 scaffold protein in the absence of Ca2+
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, Lipid scramblase nhTMEM16
Authors:Feng, Z, Accardi, A.
Deposit date:2023-08-04
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Structural basis of closed groove scrambling by a TMEM16 protein.
Nat.Struct.Mol.Biol., 2024
8TPN
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BU of 8tpn by Molmil
nhTMEM16 lipid scramblase in lipid nanodiscs with MSP2N2 scaffold protein in the presence of Ca2+ (intermediate state)
Descriptor: CALCIUM ION, Lipid scramblase nhTMEM16
Authors:Feng, Z, Accardi, A.
Deposit date:2023-08-04
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (4.07 Å)
Cite:Structural basis of closed groove scrambling by a TMEM16 protein.
Nat.Struct.Mol.Biol., 2024
8TPS
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BU of 8tps by Molmil
nhTMEM16 A444P mutant in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+ (bent TM6)
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, Lipid scramblase nhTMEM16
Authors:Feng, Z, Accardi, A.
Deposit date:2023-08-04
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Structural basis of closed groove scrambling by a TMEM16 protein.
Nat.Struct.Mol.Biol., 2024
8TOL
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BU of 8tol by Molmil
nhTMEM16 lipid scramblase in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+ (open state)
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, Lipid scramblase nhTMEM16
Authors:Feng, Z, Accardi, A.
Deposit date:2023-08-03
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Structural basis of closed groove scrambling by a TMEM16 protein.
Nat.Struct.Mol.Biol., 2024
8TOI
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BU of 8toi by Molmil
nhTMEM16 lipid scramblase in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+ (closed state)
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, Lipid scramblase nhTMEM16
Authors:Feng, Z, Accardi, A.
Deposit date:2023-08-03
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:Structural basis of closed groove scrambling by a TMEM16 protein.
Nat.Struct.Mol.Biol., 2024

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PDB entries from 2024-08-28

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