6OY3

nhTMEM16 L302A +Ca2+ in nanodiscs

Summary for 6OY3

Entry DOI	10.2210/pdb6oy3/pdb
EMDB information	20221
Descriptor	nhTMEM16, CALCIUM ION (2 entities in total)
Functional Keywords	tmem16, scramblase, lipid transport, anoactamin
Biological source	Nectria haematococca (strain 77-13-4 / ATCC MYA-4622 / FGSC 9596 / MPVI)
Total number of polymer chains	2
Total formula weight	166476.17
Authors	Falzone, M.,Lee, B.C.,Accardi, A. (deposition date: 2019-05-14, release date: 2019-11-06, Last modification date: 2024-03-20)
Primary citation	Khelashvili, G.,Falzone, M.E.,Cheng, X.,Lee, B.C.,Accardi, A.,Weinstein, H. Dynamic modulation of the lipid translocation groove generates a conductive ion channel in Ca 2+ -bound nhTMEM16. Nat Commun, 10:4972-4972, 2019 Cited by PubMed: 31672969 DOI: 10.1038/s41467-019-12865-4 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4 Å)

Structure validation