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7QJI
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BU of 7qji by Molmil
X-Ray Structure of apo-EleNRMT in complex with two Nanobodies at 4.1A
Descriptor: Divalent metal cation transporter, Elen-Nanobody-complex
Authors:Ramanadane, K, Straub, M.S, Dutzler, R, Manatschal, C.
Deposit date:2021-12-16
Release date:2022-02-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Structural and functional properties of a magnesium transporter of the SLC11/NRAMP family.
Elife, 11, 2022
7QJJ
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BU of 7qjj by Molmil
X-Ray Structure of a Mn2+ soak of EleNRMT in complex with two Nanobodies at 4.6A
Descriptor: Divalent metal cation transporter, Elen-Nb1-Nb2, MANGANESE (II) ION
Authors:Ramanadane, K, Straub, M.S, Dutzler, R, Manatschal, C.
Deposit date:2021-12-16
Release date:2022-02-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (4.6 Å)
Cite:Structural and functional properties of a magnesium transporter of the SLC11/NRAMP family.
Elife, 11, 2022
6RTF
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BU of 6rtf by Molmil
Structure of murine Solute Carrier 26 family member A9 (Slc26a9) anion transporter in an intermediate state
Descriptor: Solute carrier family 26 member 9,Solute carrier family 26 member 9
Authors:Sawicka, M, Walter, J.D, Dutzler, R.
Deposit date:2019-05-23
Release date:2019-07-24
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (7.77 Å)
Cite:Cryo-EM structures and functional characterization of murine Slc26a9 reveal mechanism of uncoupled chloride transport.
Elife, 8, 2019
6RTC
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BU of 6rtc by Molmil
Structure of murine Solute Carrier 26 family member A9 (Slc26a9) anion transporter in the inward-facing state
Descriptor: Solute carrier family 26 member 9,Solute carrier family 26 member 9
Authors:Sawicka, M, Walter, J.D, Dutzler, R.
Deposit date:2019-05-23
Release date:2019-07-24
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.96 Å)
Cite:Cryo-EM structures and functional characterization of murine Slc26a9 reveal mechanism of uncoupled chloride transport.
Elife, 8, 2019
6TL2
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BU of 6tl2 by Molmil
Crystal structure of Eremococcus coleocola manganese transporter in complex with an aromatic bis-isothiourea substituted compound
Descriptor: Divalent metal cation transporter MntH, [3-bromanyl-5-(carbamimidoylsulfanylmethyl)phenyl]methyl carbamimidothioate
Authors:Manatschal, C, Dutzler, R.
Deposit date:2019-11-29
Release date:2019-12-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Mechanistic basis of the inhibition of SLC11/NRAMP-mediated metal ion transport by bis-isothiourea substituted compounds.
Elife, 8, 2019
2PFI
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BU of 2pfi by Molmil
Crystal structure of the cytoplasmic domain of the human chloride channel ClC-Ka
Descriptor: CHLORIDE ION, Chloride channel protein ClC-Ka, IODIDE ION
Authors:Markovic, S, Dutzler, R.
Deposit date:2007-04-05
Release date:2007-06-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The Structure of the Cytoplasmic Domain of the Chloride Channel ClC-Ka Reveals a Conserved Interaction Interface.
Structure, 15, 2007
2VL0
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BU of 2vl0 by Molmil
X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC)
Descriptor: Cys-loop ligand-gated ion channel
Authors:Hilf, R.J.C, Dutzler, R.
Deposit date:2008-01-07
Release date:2008-03-11
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:X-Ray Structure of a Prokaryotic Pentameric Ligand-Gated Ion Channel
Nature, 452, 2008
3EI0
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BU of 3ei0 by Molmil
Structure of the E221A mutant of the Gloebacter violaceus pentameric ligand gated ion channnel (GLIC)
Descriptor: Glr4197 protein
Authors:Hilf, R.J.C, Dutzler, R.
Deposit date:2008-09-15
Release date:2008-11-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel
Nature, 457, 2008
3EHZ
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BU of 3ehz by Molmil
X-ray structure of the pentameric ligand gated ion channel of Gloebacter violaceus (GLIC) in a presumptive open conformation
Descriptor: Glr4197 protein
Authors:Hilf, R.J.C, Dutzler, R.
Deposit date:2008-09-15
Release date:2008-11-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel
Nature, 457, 2008
6FNW
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BU of 6fnw by Molmil
Structure of a volume-regulated anion channel of the LRRC8 family
Descriptor: 1,2-ETHANEDIOL, Volume-regulated anion channel subunit LRRC8A
Authors:Deneka, D, Sawicka, M, Lam, A.K.M, Paulino, C, Dutzler, R.
Deposit date:2018-02-05
Release date:2018-05-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of a volume-regulated anion channel of the LRRC8 family.
Nature, 558, 2018
6G9O
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BU of 6g9o by Molmil
Structure of full-length homomeric mLRRC8A volume-regulated anion channel at 4.25 A resolution
Descriptor: Volume-regulated anion channel subunit LRRC8A
Authors:Sawicka, M, Deneka, D, Lam, A.K.M, Paulino, C, Dutzler, R.
Deposit date:2018-04-11
Release date:2018-05-16
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.25 Å)
Cite:Structure of a volume-regulated anion channel of the LRRC8 family.
Nature, 558, 2018
6G8Z
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BU of 6g8z by Molmil
Structure of the pore domain of homomeric mLRRC8A volume-regulated anion channel at 3.66 A resolution
Descriptor: Volume-regulated anion channel subunit LRRC8A
Authors:Sawicka, M, Deneka, D, Lam, A.K.M, Paulino, C, Dutzler, R.
Deposit date:2018-04-10
Release date:2018-05-16
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:Structure of a volume-regulated anion channel of the LRRC8 family.
Nature, 558, 2018
6G9L
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BU of 6g9l by Molmil
Structure of homomeric mLRRC8A volume-regulated anion channel at 5.01 A resolution
Descriptor: Volume-regulated anion channel subunit LRRC8A
Authors:Sawicka, M, Deneka, D, Lam, A.K.M, Paulino, C, Dutzler, R.
Deposit date:2018-04-11
Release date:2018-05-16
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (5.01 Å)
Cite:Structure of a volume-regulated anion channel of the LRRC8 family.
Nature, 558, 2018
3G40
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BU of 3g40 by Molmil
Crystal structure of the cytoplasmic domain of a prokaryotic cation chloride cotransporter
Descriptor: Na-K-Cl cotransporter
Authors:Warmuth, S, Zimmermann, I, Dutzler, R.
Deposit date:2009-02-03
Release date:2009-04-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray Structure of the C-Terminal Domain of a Prokaryotic Cation-Chloride Cotransporter
Structure, 17, 2009
2XQ5
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BU of 2xq5 by Molmil
Pentameric ligand gated ion channel GLIC in complex with tetraethylarsonium (TEAs)
Descriptor: ARSENIC, GLR4197 PROTEIN
Authors:Hilf, R.J.C, Bertozzi, C, Zimmermann, I, Reiter, A, Trauner, D, Dutzler, R.
Deposit date:2010-09-01
Release date:2010-11-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural Basis of Open Channel Block in a Prokaryotic Pentameric Ligand-Gated Ion Channel
Nat.Struct.Mol.Biol., 17, 2010
2XQ7
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BU of 2xq7 by Molmil
Pentameric ligand gated ion channel GLIC in complex with cadmium ion (Cd2+)
Descriptor: CADMIUM ION, GLR4197 PROTEIN
Authors:Hilf, R.J.C, Bertozzi, C, Zimmermann, I, Reiter, A, Trauner, D, Dutzler, R.
Deposit date:2010-09-01
Release date:2010-11-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural Basis of Open Channel Block in a Prokaryotic Pentameric Ligand-Gated Ion Channel
Nat.Struct.Mol.Biol., 17, 2010
2XQ8
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BU of 2xq8 by Molmil
Pentameric ligand gated ion channel GLIC in complex with zinc ion (Zn2+)
Descriptor: GLR4197 PROTEIN, ZINC ION
Authors:Hilf, R.J.C, Bertozzi, C, Zimmermann, I, Reiter, A, Trauner, D, Dutzler, R.
Deposit date:2010-09-01
Release date:2010-11-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural Basis of Open Channel Block in a Prokaryotic Pentameric Ligand-Gated Ion Channel
Nat.Struct.Mol.Biol., 17, 2010
2XQ3
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BU of 2xq3 by Molmil
Pentameric ligand gated ion channel GLIC in complex with Br-lidocaine
Descriptor: BROMIDE ION, GLR4197 PROTEIN
Authors:Hilf, R.J.C, Bertozzi, C, Zimmermann, I, Reiter, A, Trauner, D, Dutzler, R.
Deposit date:2010-09-01
Release date:2010-11-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural Basis of Open Channel Block in a Prokaryotic Pentameric Ligand-Gated Ion Channel
Nat.Struct.Mol.Biol., 17, 2010
2XQA
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BU of 2xqa by Molmil
Pentameric ligand gated ion channel GLIC in complex with tetrabutylantimony (TBSb)
Descriptor: ANTIMONY (III) ION, GLR4197 PROTEIN
Authors:Hilf, R.J.C, Bertozzi, C, Zimmermann, I, Reiter, A, Trauner, D, Dutzler, R.
Deposit date:2010-09-01
Release date:2010-11-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structural Basis of Open Channel Block in a Prokaryotic Pentameric Ligand-Gated Ion Channel
Nat.Struct.Mol.Biol., 17, 2010
2XQ6
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BU of 2xq6 by Molmil
Pentameric ligand gated ion channel GLIC in complex with cesium ion (Cs+)
Descriptor: CESIUM ION, GLR4197 PROTEIN
Authors:Hilf, R.J.C, Bertozzi, C, Zimmermann, I, Reiter, A, Trauner, D, Dutzler, R.
Deposit date:2010-09-01
Release date:2010-11-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structural Basis of Open Channel Block in a Prokaryotic Pentameric Ligand-Gated Ion Channel
Nat.Struct.Mol.Biol., 17, 2010
2XQ4
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BU of 2xq4 by Molmil
Pentameric ligand gated ion channel GLIC in complex with tetramethylarsonium (TMAs)
Descriptor: ARSENIC, GLR4197 PROTEIN
Authors:Hilf, R.J.C, Bertozzi, C, Zimmermann, I, Reiter, A, Trauner, D, Dutzler, R.
Deposit date:2010-09-01
Release date:2010-11-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural Basis of Open Channel Block in a Prokaryotic Pentameric Ligand-Gated Ion Channel
Nat.Struct.Mol.Biol., 17, 2010
2XQ9
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BU of 2xq9 by Molmil
Pentameric ligand gated ion channel GLIC mutant E221A in complex with tetraethylarsonium (TEAs)
Descriptor: ARSENIC, GLR4197 PROTEIN
Authors:Hilf, R.J.C, Bertozzi, C, Zimmermann, I, Reiter, A, Trauner, D, Dutzler, R.
Deposit date:2010-09-01
Release date:2010-11-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Basis of Open Channel Block in a Prokaryotic Pentameric Ligand-Gated Ion Channel
Nat.Struct.Mol.Biol., 17, 2010
7ZK3
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BU of 7zk3 by Molmil
Structure of 1PBC- and calcium-bound mTMEM16A(ac) chloride channel at 2.85 A resolution
Descriptor: 1-Hydroxy-3-(trifluoromethyl)pyrido[1,2-a]benzimidazole-4-carbonitrile, Anoctamin-1, CALCIUM ION
Authors:Lam, A.K.M, Rutz, S, Dutzler, R.
Deposit date:2022-04-12
Release date:2022-05-25
Last modified:2022-06-01
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Inhibition mechanism of the chloride channel TMEM16A by the pore blocker 1PBC.
Nat Commun, 13, 2022
8B40
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BU of 8b40 by Molmil
Structure of homomeric LRRC8C Volume-Regulated Anion Channel
Descriptor: Volume-regulated anion channel subunit LRRC8C
Authors:Sawicka, M, Dutzler, R.
Deposit date:2022-09-19
Release date:2022-12-14
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structure of a volume-regulated heteromeric LRRC8A/C channel.
Nat.Struct.Mol.Biol., 30, 2023
8B41
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BU of 8b41 by Molmil
Structure of heteromeric LRRC8A/C (1:1 co-transfected) Volume-Regulated Anion Channel in complex with synthetic nanobody Sb1
Descriptor: Synthetic nanobody Sb1, Volume-regulated anion channel subunit LRRC8A, Volume-regulated anion channel subunit LRRC8C
Authors:Sawicka, M, Dutzler, R.
Deposit date:2022-09-19
Release date:2022-12-14
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of a volume-regulated heteromeric LRRC8A/C channel.
Nat.Struct.Mol.Biol., 30, 2023

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