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6TL2

Crystal structure of Eremococcus coleocola manganese transporter in complex with an aromatic bis-isothiourea substituted compound

Summary for 6TL2
Entry DOI10.2210/pdb6tl2/pdb
DescriptorDivalent metal cation transporter MntH, [3-bromanyl-5-(carbamimidoylsulfanylmethyl)phenyl]methyl carbamimidothioate (2 entities in total)
Functional Keywordsinhibitor complex, transport protein
Biological sourceEremococcus coleocola ACS-139-V-Col8
Total number of polymer chains1
Total formula weight54031.47
Authors
Manatschal, C.,Dutzler, R. (deposition date: 2019-11-29, release date: 2019-12-18, Last modification date: 2024-01-24)
Primary citationManatschal, C.,Pujol-Gimenez, J.,Poirier, M.,Reymond, J.L.,Hediger, M.A.,Dutzler, R.
Mechanistic basis of the inhibition of SLC11/NRAMP-mediated metal ion transport by bis-isothiourea substituted compounds.
Elife, 8:-, 2019
Cited by
PubMed: 31804182
DOI: 10.7554/eLife.51913
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.8 Å)
Structure validation

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PDB entries from 2024-03-27

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