2F8T
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3PT9
| Crystal structure of mouse DNMT1(731-1602) in the free state | Descriptor: | DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION | Authors: | Song, J, Patel, D.J. | Deposit date: | 2010-12-02 | Release date: | 2010-12-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation. Science, 331, 2011
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4QLN
| structure of ydao riboswitch binding with c-di-dAMP | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, MAGNESIUM ION, RNA (117-MER) | Authors: | Ren, A.M, Patel, D.J. | Deposit date: | 2014-06-12 | Release date: | 2014-08-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | c-di-AMP binds the ydaO riboswitch in two pseudo-symmetry-related pockets. Nat.Chem.Biol., 10, 2014
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3RAX
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2JSL
| Monomeric Human Telomere DNA Tetraplex with 3+1 Strand Fold Topology, Two Edgewise Loops and Double-Chain Reversal Loop, Form 2 Natural, NMR, 10 Structures | Descriptor: | HUMAN TELOMERE DNA | Authors: | Kuryavyi, V.V, Phan, A.T, Luu, K.N, Patel, D.J. | Deposit date: | 2007-07-08 | Release date: | 2008-07-15 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution. Nucleic Acids Res., 35, 2007
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3RV1
| Crystal structure of the N-terminal and RNase III domains of K. polysporus Dcr1 E224Q mutant | Descriptor: | K. polysporus Dcr1 | Authors: | Nakanishi, K, Weinberg, D.E, Bartel, D.P, Patel, D.J. | Deposit date: | 2011-05-05 | Release date: | 2011-08-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.975 Å) | Cite: | The inside-out mechanism of dicers from budding yeasts. Cell(Cambridge,Mass.), 146, 2011
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4QXC
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4QXO
| Crystal structure of hSTING(group2) in complex with DMXAA | Descriptor: | (5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid, Stimulator of interferon genes protein | Authors: | Gao, P, Patel, D.J. | Deposit date: | 2014-07-21 | Release date: | 2014-09-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA. Cell Rep, 8, 2014
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3RW6
| Structure of nuclear RNA export factor TAP bound to CTE RNA | Descriptor: | Nuclear RNA export factor 1, constitutive transport element(CTE)of Mason-Pfizer monkey virus RNA | Authors: | Teplova, M, Khin, N.W, Patel, D.J, Izaurralde, E. | Deposit date: | 2011-05-07 | Release date: | 2011-08-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure-function studies of nucleocytoplasmic transport of retroviral genomic RNA by mRNA export factor TAP. Nat.Struct.Mol.Biol., 18, 2011
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2JSQ
| Monomeric Human Telomere DNA Tetraplex with 3+1 Strand Fold Topology, Two Edgewise Loops and Double-Chain Reversal Loop, Form 2 15BrG, NMR, 10 Structures | Descriptor: | HUMAN TELOMERE DNA | Authors: | Kuryavyi, V.V, Phan, A.T, Luu, K.N, Patel, D.J. | Deposit date: | 2007-07-11 | Release date: | 2008-07-15 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution. Nucleic Acids Res., 35, 2007
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3O36
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3O3I
| Crystal Structure of human Hiwi1 PAZ domain (residues 277-399) in complex with 14-mer RNA (12-bp + 2-nt overhang) containing 2'-OH at its 3'-end | Descriptor: | Piwi-like protein 1, RNA (5'-R(*GP*CP*GP*AP*AP*UP*AP*UP*UP*CP*GP*CP*UP*U)-3') | Authors: | Tian, Y, Simanshu, D.K, Ma, J.-B, Patel, D.J. | Deposit date: | 2010-07-24 | Release date: | 2011-01-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.801 Å) | Cite: | Inaugural Article: Structural basis for piRNA 2'-O-methylated 3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille) domains. Proc.Natl.Acad.Sci.USA, 108, 2011
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3NNC
| Crystal Structure of CUGBP1 RRM1/2-RNA Complex | Descriptor: | CUGBP Elav-like family member 1, RNA (5'-R(*UP*GP*UP*GP*UP*GP*UP*UP*GP*UP*GP*UP*G)-3') | Authors: | Teplova, M, Song, J, Gaw, H, Teplov, A, Patel, D.J. | Deposit date: | 2010-06-23 | Release date: | 2010-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2005 Å) | Cite: | Structural Insights into RNA Recognition by the Alternate-Splicing Regulator CUG-Binding Protein 1. Structure, 18, 2010
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3O35
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3RWV
| Crystal Structure of apo-form of Human Glycolipid Transfer Protein at 1.5 A resolution | Descriptor: | Glycolipid transfer protein, SULFATE ION | Authors: | Samygina, V, Cabo-Bilbao, A, Popov, A.N, Ochoa-Lizarralde, B, Goni-de-Cerio, F, Patel, D.J, Brown, R.E, Malinina, L. | Deposit date: | 2011-05-09 | Release date: | 2012-02-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Enhanced selectivity for sulfatide by engineered human glycolipid transfer protein. Structure, 19, 2011
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3S0K
| Crystal Structure of Human Glycolipid Transfer Protein complexed with glucosylceramide containing oleoyl acyl chain (18:1) | Descriptor: | (9Z)-N-[(2S,3R,4E)-1-(beta-D-glucopyranosyloxy)-3-hydroxyoctadec-4-en-2-yl]octadec-9-enamide, Glycolipid transfer protein, NICKEL (II) ION | Authors: | Cabo-Bilbao, A, Samygina, V, Popov, A.N, Ochoa-Lizarralde, B, Goni-de-Cerio, F, Patel, D.J, Brown, R.E, Malinina, L. | Deposit date: | 2011-05-13 | Release date: | 2012-02-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Enhanced selectivity for sulfatide by engineered human glycolipid transfer protein. Structure, 19, 2011
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3RW7
| Structure of N-terminal domain of nuclear RNA export factor TAP | Descriptor: | Nuclear RNA export factor 1 | Authors: | Teplova, M, Khin, N.W, Wohlbold, L, Izaurralde, E, Patel, D.J. | Deposit date: | 2011-05-07 | Release date: | 2011-08-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure-function studies of nucleocytoplasmic transport of retroviral genomic RNA by mRNA export factor TAP. Nat.Struct.Mol.Biol., 18, 2011
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3S0I
| Crystal Structure of D48V mutant of Human Glycolipid Transfer Protein complexed with 3-O-sulfo galactosylceramide containing nervonoyl acyl chain | Descriptor: | (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE, Glycolipid transfer protein | Authors: | Samygina, V, Popov, A.N, Cabo-Bilbao, A, Ochoa-Lizarralde, B, Patel, D.J, Brown, R.E, Malinina, L. | Deposit date: | 2011-05-13 | Release date: | 2012-02-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Enhanced selectivity for sulfatide by engineered human glycolipid transfer protein. Structure, 19, 2011
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3RV0
| Crystal structure of K. polysporus Dcr1 without the C-terminal dsRBD | Descriptor: | K. polysporus Dcr1, MAGNESIUM ION | Authors: | Nakanishi, K, Weinberg, D.E, Bartel, D.P, Patel, D.J. | Deposit date: | 2011-05-05 | Release date: | 2011-08-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | The inside-out mechanism of dicers from budding yeasts. Cell(Cambridge,Mass.), 146, 2011
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3RZN
| Crystal Structure of Human Glycolipid Transfer Protein complexed with 3-O-sulfo-galactosylceramide containing nervonoyl acyl chain (24:1) | Descriptor: | (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE, Glycolipid transfer protein | Authors: | Samygina, V, Cabo-Bilbao, A, Popov, A.N, Ochoa-Lizarralde, B, Patel, D.J, Brown, R.E, Malinina, L. | Deposit date: | 2011-05-12 | Release date: | 2012-02-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Enhanced selectivity for sulfatide by engineered human glycolipid transfer protein. Structure, 19, 2011
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3SLM
| Crystal structure of the 2'- Deoxyguanosine riboswitch bound to 2'-deoxyguanosine-5'-monophosphate | Descriptor: | 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, RNA (68-MER), ... | Authors: | Pikovskaya, O, Polonskaia, A, Patel, D.J, Serganov, A.A. | Deposit date: | 2011-06-24 | Release date: | 2011-08-17 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural principles of nucleoside selectivity in a 2'-deoxyguanosine riboswitch. Nat.Chem.Biol., 7, 2011
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2JMJ
| NMR solution structure of the PHD domain from the yeast YNG1 protein in complex with H3(1-9)K4me3 peptide | Descriptor: | Histone H3, Protein YNG1, ZINC ION | Authors: | Ilin, S, Taverna, S.D, Rogers, R.S, Tanny, J.C, Lavender, H, Li, H, Baker, L, Boyle, J, Blair, L.P, Chait, B.T, Patel, D.J, Aitchison, J.D, Tackett, A.J, Allis, C.D. | Deposit date: | 2006-11-15 | Release date: | 2007-07-03 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs Mol.Cell, 24, 2006
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6PPU
| Cryo-EM structure of AdnAB-AMPPNP-DNA complex | Descriptor: | ATP-dependent DNA helicase (UvrD/REP), DNA (29-MER), IRON/SULFUR CLUSTER, ... | Authors: | Jia, N, Unciuleac, M, Shuman, S, Patel, D.J. | Deposit date: | 2019-07-08 | Release date: | 2019-11-20 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structures and single-molecule analysis of bacterial motor nuclease AdnAB illuminate the mechanism of DNA double-strand break resection. Proc.Natl.Acad.Sci.USA, 116, 2019
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2PIK
| CALICHEAMICIN GAMMA1I-DNA COMPLEX, NMR, 6 STRUCTURES | Descriptor: | 2,4-dideoxy-4-(ethylamino)-3-O-methyl-alpha-L-threo-pentopyranose-(1-2)-4-amino-4,6-dideoxy-beta-D-glucopyranose, 2,6-dideoxy-4-thio-beta-D-allopyranose, 3-O-methyl-alpha-L-rhamnopyranose, ... | Authors: | Kumar, R.A, Ikemoto, N, Patel, D.J. | Deposit date: | 1996-12-31 | Release date: | 1997-05-15 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of the calicheamicin gamma 1I-DNA complex. J.Mol.Biol., 265, 1997
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2KYP
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