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4P94
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The crystal structure of the soluble domain of Sulfolobus acidocaldarius FlaF (residues 35-164)
Descriptor: Conserved flagellar protein F, SODIUM ION
Authors:Tsai, C.-L, Arvai, A.S, Ishida, J.P, Tainer, J.A.
Deposit date:2014-04-02
Release date:2015-04-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.651 Å)
Cite:FlaF Is a beta-Sandwich Protein that Anchors the Archaellum in the Archaeal Cell Envelope by Binding the S-Layer Protein.
Structure, 23, 2015
4O24
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DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities
Descriptor: (5~{Z})-5-[(4-hydroxyphenyl)methylidene]-3-(2-methylpropyl)-2-sulfanylidene-1,3-thiazolidin-4-one, Exonuclease, putative, ...
Authors:Shibata, A, Moiani, D, Arvai, A.S, Perry, J, Harding, S.M, Genois, M, Maity, R, Rossum-Fikkert, S, Kertokalio, A, Romoli, F, Ismail, A, Ismalaj, E, Petricci, E, Neale, M.J, Bristow, R.G, Masson, J, Wyman, C, Jeggo, P.A, Tainer, J.A.
Deposit date:2013-12-16
Release date:2014-01-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities.
Mol.Cell, 53, 2014
4O4K
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DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities
Descriptor: (5~{E})-2-azanylidene-5-[(4-hydroxyphenyl)methylidene]-1,3-thiazolidin-4-one, Exonuclease, putative, ...
Authors:Shibata, A, Moiani, D, Arvai, A.S, Perry, J, Harding, S.M, Genois, M, Maity, R, Rossum-Fikkert, S, Kertokalio, A, Romoli, F, Ismail, A, Ismalaj, E, Petricci, E, Neale, M.J, Bristow, R.G, Masson, J, Wyman, C, Jeggo, P.A, Tainer, J.A.
Deposit date:2013-12-18
Release date:2014-01-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities.
Mol.Cell, 53, 2014
4PPE
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BU of 4ppe by Molmil
human RNF4 RING domain
Descriptor: E3 ubiquitin-protein ligase RNF4, ZINC ION
Authors:Perry, J.J, Arvai, A.S, Hitomi, C, Tainer, J.A.
Deposit date:2014-02-26
Release date:2014-03-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:RNF4 interacts with both SUMO and nucleosomes to promote the DNA damage response.
Embo Rep., 15, 2014
4O43
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DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities
Descriptor: (5~{E})-3-[(2~{R})-butan-2-yl]-5-[(4-hydroxyphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one, Exonuclease, putative, ...
Authors:Shibata, A, Moiani, D, Arvai, A.S, Perry, J, Harding, S.M, Genois, M, Maity, R, Rossum-Fikkert, S, Kertokalio, A, Romoli, F, Ismail, A, Ismalaj, E, Petricci, E, Neale, M.J, Bristow, R.G, Masson, J, Wyman, C, Jeggo, P.A, Tainer, J.A.
Deposit date:2013-12-18
Release date:2014-01-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities.
Mol.Cell, 53, 2014
4O5G
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DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities
Descriptor: (5~{E})-5-[(4-aminophenyl)methylidene]-2-azanylidene-1,3-thiazolidin-4-one, Exonuclease, putative, ...
Authors:Shibata, A, Moiani, D, Arvai, A.S, Perry, J, Harding, S.M, Genois, M, Maity, R, Rossum-Fikkert, S, Kertokalio, A, Romoli, F, Ismail, A, Ismalaj, E, Petricci, E, Neale, M.J, Bristow, R.G, Masson, J, Wyman, C, Jeggo, P.A, Tainer, J.A.
Deposit date:2013-12-19
Release date:2014-01-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities.
Mol.Cell, 53, 2014
4EEU
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Crystal structure of phiLOV2.1
Descriptor: FLAVIN MONONUCLEOTIDE, Phototropin-2
Authors:Hitomi, K, Christie, J.M, Arvai, A.S, Hartfield, K.A, Pratt, A.J, Tainer, J.A, Getzoff, E.D.
Deposit date:2012-03-28
Release date:2012-05-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.4068 Å)
Cite:Structural Tuning of the Fluorescent Protein iLOV for Improved Photostability.
J.Biol.Chem., 287, 2012
1GUL
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BU of 1gul by Molmil
HUMAN GLUTATHIONE TRANSFERASE A4-4 COMPLEX WITH IODOBENZYL GLUTATHIONE
Descriptor: GAMMA-GLUTAMYL[S-(2-IODOBENZYL)CYSTEINYL]GLYCINE, Glutathione S-transferase A4
Authors:Bruns, C.M, Hubatsch, I, Ridderstrom, M, Mannervik, B, Tainer, J.A.
Deposit date:1998-06-10
Release date:1999-01-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Human glutathione transferase A4-4 crystal structures and mutagenesis reveal the basis of high catalytic efficiency with toxic lipid peroxidation products
J.Mol.Biol., 288, 1999
1GTA
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CRYSTAL STRUCTURES OF A SCHISTOSOMAL DRUG AND VACCINE TARGET: GLUTATHIONE S-TRANSFERASE FROM SCHISTOSOMA JAPONICA AND ITS COMPLEX WITH THE LEADING ANTISCHISTOSOMAL DRUG PRAZIQUANTEL
Descriptor: GLUTATHIONE S-TRANSFERASE
Authors:Mctigue, M.A, Tainer, J.A.
Deposit date:1994-12-01
Release date:1995-02-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of a schistosomal drug and vaccine target: glutathione S-transferase from Schistosoma japonica and its complex with the leading antischistosomal drug praziquantel.
J.Mol.Biol., 246, 1995
1GTB
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BU of 1gtb by Molmil
CRYSTAL STRUCTURES OF A SCHISTOSOMAL DRUG AND VACCINE TARGET: GLUTATHIONE S-TRANSFERASE FROM SCHISTOSOMA JAPONICA AND ITS COMPLEX WITH THE LEADING ANTISCHISTOSOMAL DRUG PRAZIQUANTEL
Descriptor: GLUTATHIONE S-TRANSFERASE, PRAZIQUANTEL
Authors:Mctigue, M.A, Tainer, J.A.
Deposit date:1994-12-01
Release date:1995-12-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of a schistosomal drug and vaccine target: glutathione S-transferase from Schistosoma japonica and its complex with the leading antischistosomal drug praziquantel.
J.Mol.Biol., 246, 1995
1GUM
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BU of 1gum by Molmil
HUMAN GLUTATHIONE TRANSFERASE A4-4 WITHOUT LIGANDS
Descriptor: PROTEIN (GLUTATHIONE TRANSFERASE A4-4)
Authors:Bruns, C.M, Hubatsch, I, Ridderstrom, M, Mannervik, B, Tainer, J.A.
Deposit date:1998-06-11
Release date:1999-01-27
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:Human glutathione transferase A4-4 crystal structures and mutagenesis reveal the basis of high catalytic efficiency with toxic lipid peroxidation products
J.Mol.Biol., 288, 1999
4ENM
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BU of 4enm by Molmil
Crystal structure of S. pombe Atl1 in complex with damaged DNA containing O6-benzylguanine
Descriptor: Alkyltransferase-like protein 1, DNA (5'-D(*CP*TP*AP*CP*TP*AP*GP*CP*CP*AP*TP*GP*G)-3'), DNA (5'-D(*GP*CP*CP*AP*TP*GP*(BZG)P*CP*TP*AP*GP*TP*A)-3')
Authors:Tubbs, J.L, Arvai, A.S, Tainer, J.A.
Deposit date:2012-04-13
Release date:2012-06-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.8402 Å)
Cite:Atl1 Regulates Choice between Global Genome and Transcription-Coupled Repair of O(6)-Alkylguanines.
Mol.Cell, 47, 2012
4ENK
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BU of 4enk by Molmil
Crystal structure of S. pombe Atl1 in complex with damaged DNA containing O6-propylguanine
Descriptor: Alkyltransferase-like protein 1, DNA (5'-D(*CP*TP*AP*CP*TP*AP*GP*CP*CP*AP*TP*GP*G)-3'), DNA (5'-D(*GP*CP*CP*AP*TP*GP*(6PO)P*CP*TP*AP*GP*TP*A)-3')
Authors:Tubbs, J.L, Arvai, A.S, Tainer, J.A.
Deposit date:2012-04-13
Release date:2012-06-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.0445 Å)
Cite:Atl1 Regulates Choice between Global Genome and Transcription-Coupled Repair of O(6)-Alkylguanines.
Mol.Cell, 47, 2012
1I3A
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BU of 1i3a by Molmil
RNASE HII FROM ARCHAEOGLOBUS FULGIDUS WITH COBALT HEXAMMINE CHLORIDE
Descriptor: COBALT HEXAMMINE(III), RIBONUCLEASE HII
Authors:Chapados, B.R, Chai, Q, Hosfield, D.J, Qiu, J, Shen, B, Tainer, J.A.
Deposit date:2001-02-13
Release date:2001-04-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural biochemistry of a type 2 RNase H: RNA primer recognition and removal during DNA replication.
J.Mol.Biol., 307, 2001
4EES
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BU of 4ees by Molmil
Crystal structure of iLOV
Descriptor: FLAVIN MONONUCLEOTIDE, Phototropin-2
Authors:Hitomi, K, Christie, J.M, Arvai, A.S, Hartfield, K.A, Pratt, A.J, Tainer, J.A, Getzoff, E.D.
Deposit date:2012-03-28
Release date:2012-05-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.805 Å)
Cite:Structural Tuning of the Fluorescent Protein iLOV for Improved Photostability.
J.Biol.Chem., 287, 2012
1I39
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BU of 1i39 by Molmil
RNASE HII FROM ARCHAEOGLOBUS FULGIDUS
Descriptor: RIBONUCLEASE HII
Authors:Chapados, B.R, Chai, Q, Hosfield, D.J, Qiu, J, Shen, B, Tainer, J.A.
Deposit date:2001-02-13
Release date:2001-04-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural biochemistry of a type 2 RNase H: RNA primer recognition and removal during DNA replication.
J.Mol.Biol., 307, 2001
4HD0
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BU of 4hd0 by Molmil
Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair
Descriptor: DNA double-strand break repair protein Mre11, MANGANESE (II) ION
Authors:Limbo, O, Moiani, D, Kertokalio, A, Wyman, C, Tainer, J.A, Russell, P.
Deposit date:2012-10-01
Release date:2012-10-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair.
Nucleic Acids Res., 40, 2012
4EER
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BU of 4eer by Molmil
Crystal structure of LOV2 domain of Arabidopsis thaliana phototropin 2 C426A mutant
Descriptor: FLAVIN MONONUCLEOTIDE, Phototropin-2
Authors:Hitomi, K, Christie, J.M, Arvai, A.S, Hartfield, K.A, Pratt, A.J, Tainer, J.A, Getzoff, E.D.
Deposit date:2012-03-28
Release date:2012-05-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.753 Å)
Cite:Structural Tuning of the Fluorescent Protein iLOV for Improved Photostability.
J.Biol.Chem., 287, 2012
1G24
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THE CRYSTAL STRUCTURE OF EXOENZYME C3 FROM CLOSTRIDIUM BOTULINUM
Descriptor: EXOENZYME C3
Authors:Han, S, Arvai, A.S, Clancy, S.B, Tainer, J.A.
Deposit date:2000-10-16
Release date:2000-12-18
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure and novel recognition motif of rho ADP-ribosylating C3 exoenzyme from Clostridium botulinum: structural insights for recognition specificity and catalysis.
J.Mol.Biol., 305, 2001
4ENJ
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BU of 4enj by Molmil
Crystal structure of S. pombe Atl1 in complex with damaged DNA containing O6-hydroxyethylguanine
Descriptor: Alkyltransferase-like protein 1, DNA (5'-D(*CP*TP*AP*CP*TP*AP*GP*CP*CP*AP*TP*GP*G)-3'), DNA (5'-D(*GP*CP*CP*AP*TP*GP*(EHG)P*CP*TP*AP*GP*TP*A)-3')
Authors:Tubbs, J.L, Arvai, A.S, Tainer, J.A.
Deposit date:2012-04-13
Release date:2012-06-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.0989 Å)
Cite:Atl1 Regulates Choice between Global Genome and Transcription-Coupled Repair of O(6)-Alkylguanines.
Mol.Cell, 47, 2012
4EET
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BU of 4eet by Molmil
Crystal structure of iLOV
Descriptor: FLAVIN MONONUCLEOTIDE, Phototropin-2
Authors:Hitomi, K, Christie, J.M, Arvai, A.S, Hartfield, K.A, Pratt, A.J, Tainer, J.A, Getzoff, E.D.
Deposit date:2012-03-28
Release date:2012-05-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural Tuning of the Fluorescent Protein iLOV for Improved Photostability.
J.Biol.Chem., 287, 2012
4ENN
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BU of 4enn by Molmil
Crystal structure of S. pombe Atl1 in complex with damaged DNA containing O6-carboxymethylguanine
Descriptor: Alkyltransferase-like protein 1, RNA (5'-R(*GP*CP*CP*AP*TP*GP*(C6G)P*CP*TP*AP*GP*TP*A)-3')
Authors:Tubbs, J.L, Arvai, A.S, Tainer, J.A.
Deposit date:2012-04-13
Release date:2012-06-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.8448 Å)
Cite:Atl1 Regulates Choice between Global Genome and Transcription-Coupled Repair of O(6)-Alkylguanines.
Mol.Cell, 47, 2012
1IN7
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BU of 1in7 by Molmil
THERMOTOGA MARITIMA RUVB R170A
Descriptor: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, HOLLIDAY JUNCTION DNA HELICASE RUVB
Authors:Putnam, C.D, Clancy, S.B, Tsuruta, H, Wetmur, J.G, Tainer, J.A.
Deposit date:2001-05-12
Release date:2001-08-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and mechanism of the RuvB Holliday junction branch migration motor.
J.Mol.Biol., 311, 2001
4EEP
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BU of 4eep by Molmil
Crystal structure of LOV2 domain of Arabidopsis thaliana phototropin 2
Descriptor: FLAVIN MONONUCLEOTIDE, Phototropin-2
Authors:Hitomi, K, Christie, J.M, Arvai, A.S, Hartfield, K.A, Pratt, A.J, Tainer, J.A, Getzoff, E.D.
Deposit date:2012-03-28
Release date:2012-05-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Tuning of the Fluorescent Protein iLOV for Improved Photostability.
J.Biol.Chem., 287, 2012
1IN6
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BU of 1in6 by Molmil
THERMOTOGA MARITIMA RUVB K64R MUTANT
Descriptor: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, COBALT (II) ION, ...
Authors:Putnam, C.D, Clancy, S.B, Tsuruta, H, Wetmur, J.G, Tainer, J.A.
Deposit date:2001-05-12
Release date:2001-08-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure and mechanism of the RuvB Holliday junction branch migration motor.
J.Mol.Biol., 311, 2001

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