1GTB

CRYSTAL STRUCTURES OF A SCHISTOSOMAL DRUG AND VACCINE TARGET: GLUTATHIONE S-TRANSFERASE FROM SCHISTOSOMA JAPONICA AND ITS COMPLEX WITH THE LEADING ANTISCHISTOSOMAL DRUG PRAZIQUANTEL

Summary for 1GTB

DescriptorGLUTATHIONE S-TRANSFERASE, PRAZIQUANTEL (3 entities in total)
Functional Keywordsglutathione transferase
Biological sourceSchistosoma japonicum
Total number of polymer chains1
Total molecular weight25847.13
Authors
Mctigue, M.A.,Tainer, J.A. (deposition date: 1994-12-01, release date: 1995-12-01, Last modification date: 2011-07-13)
Primary citation
McTigue, M.A.,Williams, D.R.,Tainer, J.A.
Crystal structures of a schistosomal drug and vaccine target: glutathione S-transferase from Schistosoma japonica and its complex with the leading antischistosomal drug praziquantel.
J.Mol.Biol., 246:21-27, 1995
PubMed: 7853399 (PDB entries with the same primary citation)
DOI: 10.1006/jmbi.1994.0061
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.6 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers241.4%15.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution