1BIO
| HUMAN COMPLEMENT FACTOR D IN COMPLEX WITH ISATOIC ANHYDRIDE INHIBITOR | Descriptor: | COMPLEMENT FACTOR D, GLYCEROL, ISATOIC ANHYDRIDE | Authors: | Jing, H, Babu, Y.S, Moore, D, Kilpatrick, J.M, Liu, X.-Y, Volanakis, J.E, Narayana, S.V.L. | Deposit date: | 1998-06-18 | Release date: | 1999-06-22 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structures of native and complexed complement factor D: implications of the atypical His57 conformation and self-inhibitory loop in the regulation of specific serine protease activity. J.Mol.Biol., 282, 1998
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1DST
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1FDP
| PROENZYME OF HUMAN COMPLEMENT FACTOR D, RECOMBINANT PROFACTOR D | Descriptor: | PROENZYME OF COMPLEMENT FACTOR D | Authors: | Jing, H, Macon, K.J, Moore, D, Delucas, L.J, Volanakis, J.E, Narayana, S.V.L. | Deposit date: | 1998-12-03 | Release date: | 1999-12-03 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis of profactor D activation: from a highly flexible zymogen to a novel self-inhibited serine protease, complement factor D. Embo J., 18, 1999
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1HFD
| HUMAN COMPLEMENT FACTOR D IN A P21 CRYSTAL FORM | Descriptor: | COMPLEMENT FACTOR D | Authors: | Jing, H, Babu, Y.S, Moore, D, Kilpatrick, J.M, Liu, X.-Y, Volanakis, J.E, Narayana, S.V.L. | Deposit date: | 1998-06-18 | Release date: | 1999-06-22 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of native and complexed complement factor D: implications of the atypical His57 conformation and self-inhibitory loop in the regulation of specific serine protease activity. J.Mol.Biol., 282, 1998
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1LJ7
| Crystal structure of calcium-depleted human C-reactive protein from perfectly twinned data | Descriptor: | C-reactive protein | Authors: | Ramadan, M.A, Shrive, A.K, Holden, D, Myles, D.A, Volanakis, J.E, DeLucas, L.J, Greenhough, T.J. | Deposit date: | 2002-04-19 | Release date: | 2002-06-05 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | The three-dimensional structure of calcium-depleted human C-reactive protein from perfectly twinned crystals. Acta Crystallogr.,Sect.D, 58, 2002
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1DSU
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1RTK
| Crystal Structure Analysis of the Bb segment of Factor B complexed with 4-guanidinobenzoic acid | Descriptor: | 4-carbamimidamidobenzoic acid, Complement factor B Bb fragment, IODIDE ION, ... | Authors: | Ponnuraj, K, Xu, Y, Macon, K, Moore, D, Volanakis, J.E, Narayana, S.V. | Deposit date: | 2003-12-10 | Release date: | 2004-12-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural analysis of engineered Bb fragment of complement factor B: insights into the activation mechanism of the alternative pathway C3-convertase. Mol.Cell, 14, 2004
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1RRK
| Crystal Structure Analysis of the Bb segment of Factor B | Descriptor: | COBALT (II) ION, Complement factor B, IODIDE ION, ... | Authors: | Ponnuraj, K, Xu, Y, Macon, K, Moore, D, Volanakis, J.E, Narayana, S.V. | Deposit date: | 2003-12-08 | Release date: | 2004-12-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural analysis of engineered Bb fragment of complement factor B: insights into the activation mechanism of the alternative pathway C3-convertase. Mol.Cell, 14, 2004
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1RS0
| Crystal Structure Analysis of the Bb segment of Factor B complexed with Di-isopropyl-phosphate (DIP) | Descriptor: | Complement factor B, DIISOPROPYL PHOSPHONATE, IODIDE ION, ... | Authors: | Ponnuraj, K, Xu, Y, Macon, K, Moore, D, Volanakis, J.E, Narayana, S.V. | Deposit date: | 2003-12-09 | Release date: | 2004-12-14 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural analysis of engineered Bb fragment of complement factor B: insights into the activation mechanism of the alternative pathway C3-convertase. Mol.Cell, 14, 2004
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1DFP
| FACTOR D INHIBITED BY DIISOPROPYL FLUOROPHOSPHATE | Descriptor: | DIISOPROPYL PHOSPHONATE, FACTOR D | Authors: | Cole, L.B, Chu, N, Kilpatrick, J.M, Volanakis, J.E, Narayana, S.V.L, Babu, Y.S. | Deposit date: | 1997-02-18 | Release date: | 1998-02-25 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of diisopropyl fluorophosphate-inhibited factor D. Acta Crystallogr.,Sect.D, 53, 1997
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1DLE
| FACTOR B SERINE PROTEASE DOMAIN | Descriptor: | COMPLEMENT FACTOR B | Authors: | Jing, H, Xu, Y, Carson, M, Moore, D, Macon, K.J, Volanakis, J.E, Narayana, S.V. | Deposit date: | 1999-12-09 | Release date: | 2000-12-13 | Last modified: | 2019-11-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | New structural motifs on the chymotrypsin fold and their potential roles in complement factor B. EMBO J., 19, 2000
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1GNH
| HUMAN C-REACTIVE PROTEIN | Descriptor: | C-REACTIVE PROTEIN, CALCIUM ION | Authors: | Shrive, A.K, Cheetham, G.M.T, Holden, D, Myles, D.A, Turnell, W.G, Volanakis, J.E, Pepys, M.B, Bloomer, A.C, Greenhough, T.J. | Deposit date: | 1996-03-01 | Release date: | 1997-01-27 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Three dimensional structure of human C-reactive protein. Nat.Struct.Biol., 3, 1996
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3FRP
| Crystal Structure of Cobra Venom Factor, a Co-factor for C3- and C5 convertase CVFBb | Descriptor: | CALCIUM ION, Cobra venom factor alpha chain, Cobra venom factor beta chain, ... | Authors: | Krishnan, V, Narayana, S.V.L. | Deposit date: | 2009-01-08 | Release date: | 2009-04-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | The Crystal Structure of Cobra Venom Factor, a Cofactor for C3- and C5-Convertase CVFBb. Structure, 17, 2009
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3ERB
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2ODQ
| Complement component C2a, the catalytic fragment of C3- and C5-convertase of human complement | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Narayana, S.V.L, Krishnan, V. | Deposit date: | 2006-12-25 | Release date: | 2007-02-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The crystal structure of c2a, the catalytic fragment of classical pathway c3 and c5 convertase of human complement. J.Mol.Biol., 367, 2007
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2ODP
| Complement component C2a, the catalytic fragment of C3- and C5-convertase of human complement | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Narayana, S.V.L, Krishnan, V. | Deposit date: | 2006-12-25 | Release date: | 2007-02-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The crystal structure of c2a, the catalytic fragment of classical pathway c3 and c5 convertase of human complement. J.Mol.Biol., 367, 2007
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1QTJ
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