1I9Z
 
 | | CRYSTAL STRUCTURE OF INOSITOL POLYPHOSPHATE 5-PHOSPHATASE DOMAIN (IPP5C) OF SPSYNAPTOJANIN IN COMPLEX WITH INOSITOL (1,4)-BISPHOSPHATE AND CALCIUM ION | | Descriptor: | CALCIUM ION, D-MYO-INOSITOL-1,4-BISPHOSPHATE, PHOSPHATIDYLINOSITOL PHOSPHATE PHOSPHATASE | | Authors: | Tsujishita, Y, Guo, S, Stolz, L, York, J.D, Hurley, J.H. | | Deposit date: | 2001-03-21 | | Release date: | 2001-05-16 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Specificity determinants in phosphoinositide dephosphorylation: crystal structure of an archetypal inositol polyphosphate 5-phosphatase.
Cell(Cambridge,Mass.), 105, 2001
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1I9Y
 | | CRYSTAL STRUCTURE OF INOSITOL POLYPHOSPHATE 5-PHOSPHATASE DOMAIN (IPP5C) OF SPSYNAPTOJANIN | | Descriptor: | PHOSPHATIDYLINOSITOL PHOSPHATE PHOSPHATASE | | Authors: | Tsujishita, Y, Guo, S, Stolz, L, York, J.D, Hurley, J.H. | | Deposit date: | 2001-03-21 | | Release date: | 2001-05-16 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Specificity determinants in phosphoinositide dephosphorylation: crystal structure of an archetypal inositol polyphosphate 5-phosphatase.
Cell(Cambridge,Mass.), 105, 2001
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1EM2
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7CMM
 | | Crystal structure of TEAD1-YBD in complex with K-975 | | Descriptor: | N-[3-(4-chloranylphenoxy)-4-methyl-phenyl]propanamide, Transcriptional enhancer factor TEF-1 | | Authors: | Tsuji, Y, Suzuki, M, Yasunaga, M, Hamguchi, K, Saito, J. | | Deposit date: | 2020-07-28 | | Release date: | 2021-02-03 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | The novel potent TEAD inhibitor, K-975, inhibits YAP1/TAZ-TEAD protein-protein interactions and exerts an anti-tumor effect on malignant pleural mesothelioma.
Am J Cancer Res, 10, 2020
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1EWV
 | | CRYSTAL STRUCTURE OF METABOTROPIC GLUTAMATE RECEPTOR SUBTYPE 1 LIGAND FREE FORM II | | Descriptor: | METABOTROPIC GLUTAMATE RECEPTOR SUBTYPE 1 | | Authors: | Kunishima, N, Shimada, Y, Tsuji, Y, Jingami, H, Morikawa, K. | | Deposit date: | 2000-04-27 | | Release date: | 2000-12-18 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (4 Å) | | Cite: | Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor.
Nature, 407, 2000
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1EWT
 | | CRYSTAL STRUCTURE OF METABOTROPIC GLUTAMATE RECEPTOR SUBTYPE 1 LIGAND FREE FORM I | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, METABOTROPIC GLUTAMATE RECEPTOR SUBTYPE 1, SULFATE ION | | Authors: | Kunishima, N, Shimada, Y, Tsuji, Y, Jingami, H, Morikawa, K. | | Deposit date: | 2000-04-27 | | Release date: | 2000-12-18 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor.
Nature, 407, 2000
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2Z6W
 | | Crystal structure of human cyclophilin D in complex with cyclosporin A | | Descriptor: | CITRIC ACID, CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE | | Authors: | Kajitani, K, Fujihashi, M, Kobayashi, Y, Shimizu, S, Tsujimoto, Y, Miki, K. | | Deposit date: | 2007-08-09 | | Release date: | 2008-04-29 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (0.96 Å) | | Cite: | Crystal Structure of Human Cyclophilin D in Complex with its Inhibitor, Cyclosporin a at 0.96-A Resolution.
Proteins, 70, 2008
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1EWK
 | | CRYSTAL STRUCTURE OF METABOTROPIC GLUTAMATE RECEPTOR SUBTYPE 1 COMPLEXED WITH GLUTAMATE | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLUTAMIC ACID, ... | | Authors: | Kunishima, N, Shimada, Y, Jingami, H, Morikawa, K. | | Deposit date: | 2000-04-26 | | Release date: | 2000-12-18 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor.
Nature, 407, 2000
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1ISS
 | | Crystal Structure of Metabotropic Glutamate Receptor Subtype 1 Complexed with an antagonist | | Descriptor: | (S)-(ALPHA)-METHYL-4-CARBOXYPHENYLGLYCINE, Metabotropic Glutamate Receptor subtype 1 | | Authors: | Tsuchiya, D, Kunishima, N, Kamiya, N, Jingami, H, Morikawa, K. | | Deposit date: | 2001-12-21 | | Release date: | 2002-03-13 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structural views of the ligand-binding cores of a metabotropic glutamate receptor complexed with an antagonist and both glutamate and Gd3+.
Proc.Natl.Acad.Sci.USA, 99, 2002
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1ISR
 | | Crystal Structure of Metabotropic Glutamate Receptor Subtype 1 Complexed with Glutamate and Gadolinium Ion | | Descriptor: | GADOLINIUM ATOM, GLUTAMIC ACID, Metabotropic Glutamate Receptor subtype 1 | | Authors: | Tsuchiya, D, Kunishima, N, Kamiya, N, Jingami, H, Morikawa, K. | | Deposit date: | 2001-12-21 | | Release date: | 2002-03-13 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (4 Å) | | Cite: | Structural views of the ligand-binding cores of a metabotropic glutamate receptor complexed with an antagonist and both glutamate and Gd3+.
Proc.Natl.Acad.Sci.USA, 99, 2002
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5IDA
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5ID8
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5IDB
 | | Crystal structure of CGL1 from Crassostrea gigas, mannose-bound form (CGL1/MAN2) | | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Natterin-3, alpha-D-mannopyranose, ... | | Authors: | Unno, H. | | Deposit date: | 2016-02-24 | | Release date: | 2016-07-06 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1 Å) | | Cite: | Identification, Characterization, and X-ray Crystallographic Analysis of a Novel Type of Mannose-Specific Lectin CGL1 from the Pacific Oyster Crassostrea gigas.
Sci Rep, 6, 2016
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2EK9
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2EK8
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6AHS
 | | Mouse Kallikrein 7 in complex with imidazolinylindole derivative | | Descriptor: | 1-[(2-chlorophenyl)sulfonyl]-5-methyl-3-[(4R)-2-methyl-4,5-dihydro-1H-imidazol-4-yl]-1H-indole, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | | Authors: | Sugawara, H. | | Deposit date: | 2018-08-20 | | Release date: | 2019-01-02 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Discovery and structure-activity relationship of imidazolinylindole derivatives as kallikrein 7 inhibitors.
Bioorg. Med. Chem. Lett., 29, 2019
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1G5M
 | | HUMAN BCL-2, ISOFORM 1 | | Descriptor: | PROTEIN (APOPTOSIS REGULATOR BCL-2 WITH PUTATIVE FLEXIBLE LOOP REPLACED WITH A PORTION OF APOPTOSIS REGULATOR BCL-X PROTEIN) | | Authors: | Petros, A.M, Medek, A, Nettesheim, D.G, Kim, D.H, Yoon, H.S, Swift, K, Matayoshi, E.D, Oltersdorf, T, Fesik, S.W. | | Deposit date: | 2000-11-01 | | Release date: | 2001-03-21 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the antiapoptotic protein bcl-2.
Proc.Natl.Acad.Sci.USA, 98, 2001
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